Megan Elizabeth Bowles Clowse, MD

Associate Professor of Medicine
Campus mail Baker House 07, Duke South, Trent Drive, Durham, NC 27710
Phone (919) 681-2045
Email address megan.clowse@duke.edu

Dr. Megan Clowse is an Associate Professor of Medicine in the Division of Rheumatology and Immunology.  Her clinical research focuses on the management of rheumatic diseases in pregnancy. She has cared for over 600 pregnancies in women with rheumatic disease, collecting information on these pregnancies initially in the Duke Autoimmunity in Pregnancy Registry and Repository, and now the MADRA (Maternal Autoimmune Disease Research Alliance) registry and repository.  She served on the Core Leadership Team for the inaugural American College of Rheumatology's Reproductive Health Guidelines, published January 2020.  Dr. Clowse created www.LupusPregnancy.org, a website dedicated to improving lupus pregnancy planning and management for patients and rheumatologists.  

Dr. Clowse was the founding director of the Duke Lupus Clinic, where she continues to see patients each week and mentor junior faculty researchers.  The team has developed a new approach to lupus classification and management and is currently collecting and analyzing patient- and physician-reported measures to  better clarify this construct.  

As the Co-Director of Duke Forge, Dr. Clowse has shepherding multiple Department of Medicine-funded studies to identify and build innovative approaches to using health data to improve patient care. 

In Their Words

Education and Training

  • Fellow in Rheumatology, Medicine, Johns Hopkins University, 2002 - 2005
  • Medical Residetn, Medicine, Johns Hopkins University, 1999 - 2002
  • M.D., Vanderbilt University, 1999
  • M.P.H., University of California - Los Angeles, 1994

Publications

Moltó, A., L. Gensler, M. E. B. Clowse, H. Marzo-Ortega, A. Artignan, D. Goff-Leggett, S. Leonard, et al. “THU0242 Pregnancy outcomes and disease activity in women with axial spondyloarthritis: a systematic literature review.” In Thursday, 14 June 2018. BMJ Publishing Group Ltd and European League Against Rheumatism, 2018. https://doi.org/10.1136/annrheumdis-2018-eular.3056.

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Vinet, Evelyne, Eliza F. Chakravarty, Julia F. Simard, and Megan Clowse. “Use of Administrative Databases to Assess Reproductive Health Issues in Rheumatic Diseases.” Rheum Dis Clin North Am 44, no. 2 (May 2018): 327–36. https://doi.org/10.1016/j.rdc.2018.01.008.

PMID
29622299
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Mollard, Elizabeth, Sofia Pedro, Eliza Chakravarty, Megan Clowse, Rebecca Schumacher, and Kaleb Michaud. “The impact of menopause on functional status in women with rheumatoid arthritis.” Rheumatology (Oxford) 57, no. 5 (May 1, 2018): 798–802. https://doi.org/10.1093/rheumatology/kex526.

PMID
29385538
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Palmsten, Kristin, Matthieu Rolland, Mary F. Hebert, Megan E. B. Clowse, Michael Schatz, Ronghui Xu, and Christina D. Chambers. “Patterns of prednisone use during pregnancy in women with rheumatoid arthritis: Daily and cumulative dose.” Pharmacoepidemiol Drug Saf 27, no. 4 (April 2018): 430–38. https://doi.org/10.1002/pds.4410.

PMID
29488292
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Mohammad, Samya, Megan E. B. Clowse, Amanda M. Eudy, and Lisa G. Criscione-Schreiber. “Examination of Hydroxychloroquine Use and Hemolytic Anemia in G6PDH-Deficient Patients.” Arthritis Care Res (Hoboken) 70, no. 3 (March 2018): 481–85. https://doi.org/10.1002/acr.23296.

PMID
28556555
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Eudy, A. M., M. Jayasundara, T. Haroun, L. Neil, A. H. James, and M. E. B. Clowse. “Reasons for cesarean and medically indicated deliveries in pregnancies in women with systemic lupus erythematosus.” Lupus 27, no. 3 (March 2018): 351–56. https://doi.org/10.1177/0961203317720525.

PMID
28699378
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Birru Talabi, Mehret, Megan E. B. Clowse, Eleanor B. Schwarz, Lisa S. Callegari, Larry Moreland, and Sonya Borrero. “Family Planning Counseling for Women With Rheumatic Diseases.” Arthritis Care Res (Hoboken) 70, no. 2 (February 2018): 169–74. https://doi.org/10.1002/acr.23267.

PMID
28437837
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Afzali, Anita, Megan E. B. Clowse, Angela E. Scheuerle, Christina Chambers, Alexa B. Kimball, John J. Cush, Maureen Cooney, Laura Shaughnessy, Mark Vanderkelen, and Frauke Förger. “28 CHARACTERISTICS AND OUTCOMES OF PROSPECTIVELY REPORTED PREGNANCIES EXPOSED TO CERTOLIZUMAB PEGOL FROM A SAFETY DATABASE.” In Inflammatory Bowel Diseases, 24:S7–S7. Oxford University Press (OUP), 2018. https://doi.org/10.1093/ibd/izy019.018.

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Afzali, Anita, Megan E. B. Clowse, Angela E. Scheuerle, Christina Chambers, Alexa B. Kimball, John J. Cush, Maureen Cooney, Laura Shaughnessy, Mark Vanderkelen, and Frauke Förger. “28 CHARACTERISTICS AND OUTCOMES OF PROSPECTIVELY REPORTED PREGNANCIES EXPOSED TO CERTOLIZUMAB PEGOL FROM A SAFETY DATABASE.” In Gastroenterology, 154:S9–10. Elsevier BV, 2018. https://doi.org/10.1053/j.gastro.2017.11.050.

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