Megan Elizabeth Bowles Clowse, MD

Associate Professor of Medicine
Campus mail Baker House 07, Duke South, Trent Drive, Durham, NC 27710
Phone (919) 681-2045
Email address megan.clowse@duke.edu

I am a clinical researcher with a focus on the management of rheumatologic diseases in pregnancy.  Since 2007, I have collected prospective pregnancies in women with rheumatic disease in the Duke Autoimmunity in Pregnancy Registry, which currently includes over 300 pregnancies.  This registry includes clinical data, pregnancy outcomes, and a large sample repository.  In collaboration with Duke Pediatric Cardiology, we found that maternal use of hydroxychloroquine may be protective against congenital heart block from neonatal lupus.  I have also conducted studies on vasculitis and ovarian function and pregnancy and I am the director of the Vasculitis-Pregnancy Registry, through the Vasculitis Clinical Research Consortium, is an online pregnancy registry for women with these rare conditions.  I am starting a study to identify causes for the high rate of infertility among women with rheumatoid arthrits.  I am also working on several projects to better understand how psoriatic arthritis impacts pregnancy.  

In Their Words

Education and Training

  • Fellow in Rheumatology, Medicine, Johns Hopkins University, 2002 - 2005
  • Medical Residetn, Medicine, Johns Hopkins University, 1999 - 2002
  • M.D., Vanderbilt University, 1999
  • M.P.H., University of California at Los Angeles, 1994

Publications

Clowse, MEB, Chakravarty, E, Costenbader, KH, Chambers, C, and Michaud, K. "Reply." Arthritis Care and Research 64, no. 11 (2012): 1785-1786.

Full Text

Clowse, MEB, Chakravarty, E, Costenbader, KH, Chambers, C, and Michaud, K. "Effects of infertility, pregnancy loss, and patient concerns on family size of women with rheumatoid arthritis and systemic lupus erythematosus." Arthritis care & research 64, no. 5 (2012): 668-674.

PMID
22344961
Full Text

Clowse, MEB, Harward, L, Criscione-Schreiber, L, Pisetsky, D, and Copland, S. "Anti-Müllerian hormone: A better marker of ovarian damage from cyclophosphamide." Arthritis and Rheumatism 64, no. 5 (2012): 1305-1310.

PMID
22354568
Full Text

Clowse, MEB, Copland, SC, Hsieh, T-C, Chow, S-C, Hoffman, GS, Merkel, PA, Spiera, RF, Davis, JC, McCune, WJ, Ytterberg, SR, St Clair, EW, Allen, NB, Specks, U, Stone, JH, and WGET Research Group, . "Ovarian reserve diminished by oral cyclophosphamide therapy for granulomatosis with polyangiitis (Wegener's)." Arthritis Care Res (Hoboken) 63, no. 12 (December 2011): 1777-1781.

PMID
22127969
Full Text

Clowse, MEB, Richesson, R, Pieper, C, Merkel, PA, and Consortium, VCR. "Infertility Among Patients with Vasculitis." October 2011.

Scholars@Duke

Kurakula, P, Somers, TJ, Criscione-Schreiber, LG, Keefe, FJ, and Clowse, MEB. "The Relationship Between Pain Coping Skills and Pain, Fatigue, Mood, and Lupus Activity." October 2011.

Scholars@Duke

Clowse, MEB, Criscione-Schreiber, LG, and Pisetsky, DS. "Predictors of Preterm Birth and Preeclampsia in Systemic Lupus Erythematosus." October 2011.

Scholars@Duke

Harward, LE, Mitchell, K, Criscione-Schreiber, LG, and Clowse, MEB. "Few Pregnancies After Cyclophosphamide Treatment Despite Preserved Ovarian Function." October 2011.

Scholars@Duke

Clowse, MEB, Richesson, R, Pieper, C, Merkel, PA, and Consortium, VCR. "Pregnancy in Men and Women with Vasculitis." October 2011.

Scholars@Duke

Clowse, MEB, Chakravarty, EF, Costenbader, KH, Chambers, C, Wolfe, F, and Michaud, K. "Contraception Use in Women with Rheumatoid Arthritis." October 2011.

Scholars@Duke

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