Megan Elizabeth Bowles Clowse, MD

Associate Professor of Medicine
Campus mail Baker House 07, Duke South, Trent Drive, Durham, NC 27710
Phone (919) 681-2045
Email address

I am a clinical researcher with a focus on the management of rheumatologic diseases in pregnancy.  Since 2007, I have collected prospective pregnancies in women with rheumatic disease in the Duke Autoimmunity in Pregnancy Registry, which currently includes over 300 pregnancies.  This registry includes clinical data, pregnancy outcomes, and a large sample repository.  In collaboration with Duke Pediatric Cardiology, we found that maternal use of hydroxychloroquine may be protective against congenital heart block from neonatal lupus.  I have also conducted studies on vasculitis and ovarian function and pregnancy and I am the director of the Vasculitis-Pregnancy Registry, through the Vasculitis Clinical Research Consortium, is an online pregnancy registry for women with these rare conditions.  I am starting a study to identify causes for the high rate of infertility among women with rheumatoid arthrits.  I am also working on several projects to better understand how psoriatic arthritis impacts pregnancy.  

In Their Words

Education and Training

  • Fellow in Rheumatology, Medicine, Johns Hopkins University, 2002 - 2005
  • Medical Residetn, Medicine, Johns Hopkins University, 1999 - 2002
  • M.D., Vanderbilt University, 1999
  • M.P.H., University of California at Los Angeles, 1994


Clowse, MEB, and Petri, M. "Pregnancy and Systemic Lupus Erythematosus." Handbook of Systemic Autoimmune Diseases 4 (2005): 43-57.

Full Text

Clowse, MEB, Magder, LS, and Petri, M. "Complement and anti-double stranded DNA antibodies predict pregnancy outcomes in lupus patients." September 2004.


Clowse, MEB, Magder, LS, and Petri, M. "Impact of the intensity and timing of lupus activity on pregnancy outcomes." September 2003.


Clowse, MEB, and Wigley, FM. "Digital necrosis related to carboplatin and gemcitabine therapy in systemic sclerosis." J Rheumatol 30, no. 6 (June 2003): 1341-1343.