Micah Thomas McClain, MD, PhD

Associate Professor of Medicine
Member of Duke Center for Applied Genomics and Precision Medicine
Campus mail Duke Box 102359, Durham, NC 27710
Phone (919) 613-5636
Email address micah.mcclain@duke.edu

Education and Training

  • Fellowship, Infectious Diseases, Duke University School of Medicine, 2006 - 2010
  • Residency, General Internal Medicine, Duke University School of Medicine, 2004 - 2006
  • M.D., University of Oklahoma, 2004
  • Ph.D., University of Oklahoma, 2002

Publications

McClain, Micah T., Florica J. Constantine, Bradly P. Nicholson, Marshall Nichols, Thomas W. Burke, Ricardo Henao, Daphne C. Jones, et al. “A blood-based host gene expression assay for early detection of respiratory viral infection: an index-cluster prospective cohort study.” Lancet Infect Dis 21, no. 3 (March 2021): 396–404. https://doi.org/10.1016/S1473-3099(20)30486-2.

PMID
32979932
Full Text

McClain, Micah T., Florica J. Constantine, Ricardo Henao, Yiling Liu, Ephraim L. Tsalik, Thomas W. Burke, Julie M. Steinbrink, et al. “Dysregulated transcriptional responses to SARS-CoV-2 in the periphery.” Nat Commun 12, no. 1 (February 17, 2021): 1079. https://doi.org/10.1038/s41467-021-21289-y.

PMID
33597532
Full Text

Tillekeratne, L Gayani, Sunil Suchindran, Emily R. Ko, Elizabeth A. Petzold, Champica K. Bodinayake, Ajith Nagahawatte, Vasantha Devasiri, et al. “Previously Derived Host Gene Expression Classifiers Identify Bacterial and Viral Etiologies of Acute Febrile Respiratory Illness in a South Asian Population.” Open Forum Infect Dis 7, no. 6 (June 2020): ofaa194. https://doi.org/10.1093/ofid/ofaa194.

PMID
32617371
Full Text

Steinbrink, Julie M., Aimee K. Zaas, Marisol Betancourt, Jennifer L. Modliszewski, David L. Corcoran, and Micah T. McClain. “A transcriptional signature accurately identifies Aspergillus Infection across healthy and immunosuppressed states.” Transl Res 219 (May 2020): 1–12. https://doi.org/10.1016/j.trsl.2020.02.005.

PMID
32165060
Full Text

McClain, Micah T., and Daniel J. Sexton. “Surveillance for Spotted Fever Group Rickettsial Infections: Problems, Pitfalls, and Potential Solutions.” J Infect Dis 221, no. 8 (March 28, 2020): 1238–40. https://doi.org/10.1093/infdis/jiz317.

PMID
31267127
Full Text

Colón-Emeric, Cathleen, Carl F. Pieper, Kenneth E. Schmader, Richard Sloane, Allison Bloom, Micah McClain, Jay Magaziner, et al. “Two Approaches to Classifying and Quantifying Physical Resilience in Longitudinal Data.” J Gerontol a Biol Sci Med Sci 75, no. 4 (March 9, 2020): 731–38. https://doi.org/10.1093/gerona/glz097.

PMID
30993327
Full Text

Jog, Neelakshi R., Micah T. McClain, Latisha D. Heinlen, Timothy Gross, Rheal Towner, Joel M. Guthridge, Robert C. Axtell, Gabriel Pardo, John B. Harley, and Judith A. James. “Epstein Barr virus nuclear antigen 1 (EBNA-1) peptides recognized by adult multiple sclerosis patient sera induce neurologic symptoms in a murine model.” J Autoimmun 106 (January 2020): 102332. https://doi.org/10.1016/j.jaut.2019.102332.

PMID
31515129
Full Text

Lydon, Emily C., Ricardo Henao, Thomas W. Burke, Mert Aydin, Bradly P. Nicholson, Seth W. Glickman, Vance G. Fowler, et al. “Validation of a host response test to distinguish bacterial and viral respiratory infection.” Ebiomedicine 48 (October 2019): 453–61. https://doi.org/10.1016/j.ebiom.2019.09.040.

PMID
31631046
Full Text

Bloom, Allison S., Sunil Suchindran, Julie Steinbrink, and Micah T. McClain. “Utility of predictive tools for risk stratification of elderly individuals with all-cause acute respiratory infection.” Infection 47, no. 4 (August 2019): 617–27. https://doi.org/10.1007/s15010-019-01299-1.

PMID
30929142
Full Text

Woods, Christopher W., Ana M. Sanchez, Geeta K. Swamy, Micah T. McClain, Lynn Harrington, Debra Freeman, Elizabeth A. Poore, et al. “An observer blinded, randomized, placebo-controlled, phase I dose escalation trial to evaluate the safety and immunogenicity of an inactivated West Nile virus Vaccine, HydroVax-001, in healthy adults.” Vaccine 37, no. 30 (July 2019): 4222–30. https://doi.org/10.1016/j.vaccine.2018.12.026.

PMID
30661836
Full Text

Pages