Micah Thomas McClain, MD, PhD

Associate Professor of Medicine
Campus mail Duke Box 102359, Durham, NC 27710
Phone (919) 613-5636
Email address micah.mcclain@duke.edu

Education and Training

  • Fellowship, Infectious Diseases, Duke University School of Medicine, 2006 - 2010
  • Residency, General Internal Medicine, Duke University School of Medicine, 2004 - 2006
  • M.D., University of Oklahoma, 2004
  • Ph.D., University of Oklahoma, 2002

Publications

Huang, Y, Zaas, AK, Rao, A, Dobigeon, N, Woolf, PJ, Veldman, T, Øien, NC, McClain, MT, Varkey, JB, Nicholson, B, Carin, L, Kingsmore, S, Woods, CW, Ginsburg, GS, and Hero, AO. "Temporal dynamics of host molecular responses differentiate symptomatic and asymptomatic influenza a infection." PLoS Genet 7, no. 8 (August 2011): e1002234-.

PMID
21901105
Full Text

Moody, MA, Zhang, R, Walter, EB, Woods, CW, Ginsburg, GS, McClain, MT, Denny, TN, Chen, X, Munshaw, S, Marshall, DJ, Whitesides, JF, Drinker, MS, Amos, JD, Gurley, TC, Eudailey, JA, Foulger, A, DeRosa, KR, Parks, R, Meyerhoff, RR, Yu, J-S, Kozink, DM, Barefoot, BE, Ramsburg, EA, Khurana, S, Golding, H, Vandergrift, NA, Alam, SM, Tomaras, GD, Kepler, TB, Kelsoe, G, Liao, H-X, and Haynes, BF. "H3N2 influenza infection elicits more cross-reactive and less clonally expanded anti-hemagglutinin antibodies than influenza vaccination." PLoS One 6, no. 10 (2011): e25797-.

PMID
22039424
Full Text

Heinlen, LD, Ritterhouse, LL, McClain, MT, Keith, MP, Neas, BR, Harley, JB, and James, JA. "Ribosomal P autoantibodies are present before SLE onset and are directed against non-C-terminal peptides." Journal of Molecular Medicine 88, no. 7 (2010): 719-727.

PMID
20396862
Full Text

Heinlen, LD, McClain, MT, Ritterhouse, LL, Bruner, BF, Edgerton, CC, Keith, MP, James, JA, and Harley, JB. "60 kD Ro and nRNP A frequently initiate human lupus autoimmunity." PLoS ONE 5, no. 3 (2010).

PMID
20224770
Full Text

Heinlen, LD, McClain, MT, Merrill, J, Akbarali, YW, Edgerton, CC, Harley, JB, and James, JA. "Clinical criteria for systemic lupus erythematosus precede diagnosis, and associated autoantibodies are present before clinical symptoms." Arthritis and Rheumatism 56, no. 7 (2007): 2344-2351.

PMID
17599763
Full Text

James, JA, Kim-Howard, XR, Bruner, BF, Jonsson, MK, McClain, MT, Arbuckle, MR, Walker, C, Dennis, GJ, Merrill, JT, and Harley, JB. "Hydroxychloroquine sulfate treatment is associated with later onset of systemic lupus erythematosus." Lupus 16, no. 6 (2007): 401-409.

PMID
17664230
Full Text

McClain, MT, Poole, BD, Bruner, BF, Kaufman, KM, Harley, JB, and James, JA. "An altered immune response to Epstein-Barr nuclear antigen 1 in pediatric systemic lupus erythematosus." Arthritis and Rheumatism 54, no. 1 (2006): 360-368.

PMID
16385527
Full Text

McClain, MT, Heinlen, LD, Dennis, GJ, Roebuck, J, Harley, JB, and James, JA. "Early events in lupus humoral autoimmunity suggest initiation through molecular mimicry." Nature Medicine 11, no. 1 (2005): 85-89.

PMID
15619631
Full Text

Scofield, RH, Kurien, BT, Ganick, S, McClain, MT, Pye, Q, James, JA, Schneider, RI, Broyles, RH, Bachmann, M, and Hensley, K. "Modification of lupus-associated 60-kDa Ro protein with the lipid oxidation product 4-hydroxy-2-nonenal increases antigenicity and facilitates epitope spreading." Free Radical Biology and Medicine 38, no. 6 (2005): 719-728.

PMID
15721982
Full Text

McClain, MT, Lutz, CS, Kaufman, KM, Faig, OZ, Gross, TF, and James, JA. "Structural availability influences the capacity of autoantigenic epitopes to induce a widespread lupus-like autoimmune response." Proceedings of the National Academy of Sciences of the United States of America 101, no. 10 (2004): 3551-3556.

PMID
14988508
Full Text

Pages