Michael August Blazing, MD

Associate Professor of Medicine
Campus mail 7412HOSP North, Durham, NC 27710
Phone (919) 681-3945
Email address blazi001@mc.duke.edu

General focus: My research interests are in primary and secondary prevention of cardiovascular disease. Specifically, I am looking at compliance issues within the cardiology division and in the University as a whole with regard to evidence based treatment and secondary prevention of cardiovascular disease. I am using both retrospective and prospective collection of discharge data to try and analyze these trends. In the future, we hope to begin clinical trials with regard to various issues which are outstanding in primary and secondary prevention. Some of the issues include treatment of hypercholesterolemia in elderly patients, differences between the various statins with regard to affects on lipid profiles, and early treatment of hypercholesterolemia after MI.

As part of my work, I have served as a consultant with various drug companies with regard to focusing on active issues and treatment of hypercholesterolemia.

Key words: Primary prevention, secondary prevention, hyperlipidemia, homocysteine, and hypertension.

In Their Words

Education and Training

  • M.D., University of California, San Francisco, School of Medicine, 1987

Publications

Whellan, D. J., L. Gaulden, W. A. Gattis, B. Granger, S. D. Russell, M. A. Blazing, M. S. Cuffe, and C. M. O’Connor. “The benefit of implementing a heart failure disease management program..” Arch Intern Med 161, no. 18 (October 8, 2001): 2223–28. https://doi.org/10.1001/archinte.161.18.2223.

PMID
11575979
Full Text

Jiang, W., J. Alexander, E. Christopher, M. Kuchibhatla, L. H. Gaulden, M. S. Cuffe, M. A. Blazing, et al. “Relationship of depression to increased risk of mortality and rehospitalization in patients with congestive heart failure..” Arch Intern Med 161, no. 15 (August 13, 2001): 1849–56. https://doi.org/10.1001/archinte.161.15.1849.

PMID
11493126
Full Text

Blazing, M. A., J. A. De Lemos, C. K. Dyke, R. M. Califf, D. Bilheimer, and E. Braunwald. “The A-to-Z Trial: Methods and rationale for a single trial investigating combined use of low-molecular-weight heparin with the glycoprotein IIb/IIIa inhibitor tirofiban and defining the efficacy of early aggressive simvastatin therapy..” Am Heart J 142, no. 2 (August 2001): 211–17. https://doi.org/10.1067/mhj.2001.116959.

PMID
11479456
Full Text

Kong, D. F., M. A. Blazing, and C. M. O’Connor. “Advances in the approach to acute coronary syndromes..” Hosp Pract (1995) 35, no. 4 (April 15, 2000): 61–64.

PMID
10780184
Scholars@Duke

Guyton, J. R., M. A. Blazing, J. Hagar, M. L. Kashyap, R. H. Knopp, J. M. McKenney, D. T. Nash, and S. D. Nash. “Extended-release niacin vs gemfibrozil for the treatment of low levels of high-density lipoprotein cholesterol. Niaspan-Gemfibrozil Study Group..” Archives of Internal Medicine 160, no. 8 (April 2000): 1177–84. https://doi.org/10.1001/archinte.160.8.1177.

Full Text

Orloff, D. G., M. A. Blazing, and C. M. O’Connor. “Atherosclerotic disease in non-insulin-dependent diabetes mellitus: role of abnormal lipids and the place for lipid-altering therapies..” Am Heart J 138, no. 5 Pt 1 (November 1999): S406–12. https://doi.org/10.1016/s0002-8703(99)70043-8.

PMID
10539805
Full Text

Blazing, M. A., and C. M. O’Connor. “Evidence supporting secondary prevention strategies..” Curr Opin Cardiol 14, no. 4 (July 1999): 303–9.

PMID
10448610
Scholars@Duke

Kong, D. F., M. A. Blazing, and C. M. O’Connor. “The health care burden of unstable angina..” Cardiol Clin 17, no. 2 (May 1999): 247–61.

PMID
10384824
Scholars@Duke

Channon, K. M., H. Qian, V. Neplioueva, M. A. Blazing, E. Olmez, G. A. Shetty, S. A. Youngblood, et al. “In vivo gene transfer of nitric oxide synthase enhances vasomotor function in carotid arteries from normal and cholesterol-Fed rabbits..” Circulation 98, no. 18 (November 3, 1998): 1905–11. https://doi.org/10.1161/01.cir.98.18.1905.

PMID
9799212
Full Text

Channon, K. M., H. S. Qian, S. A. Youngblood, E. Olmez, G. A. Shetty, V. Neplioueva, M. A. Blazing, and S. E. George. “Acute host-mediated endothelial injury after adenoviral gene transfer in normal rabbit arteries: impact on transgene expression and endothelial function..” Circ Res 82, no. 12 (June 29, 1998): 1253–62. https://doi.org/10.1161/01.res.82.12.1253.

PMID
9648721
Full Text

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