Myles Selig Wolf, MD

Professor of Medicine
Charles Johnson, M.D. Distinguished Professor of Medicine
Chief of Nephrology
Professor in Population Health Sciences
Member of the Duke Clinical Research Institute
Email address
Fax: 919-684-3011

The focus of my research is disordered mineral metabolism across the spectrum of chronic kidney disease, including dialysis, kidney transplantation and earlier stages.

My research has been published in leading general medicine and subspecialty journals, including the New England Journal of Medicine, JAMA, the Journal of Clinical Investigation, Circulation, Cell Metabolism, Journal of the American Society of Nephrology, and Kidney International, among others.

My primary contributions have been in the area of hormonal regulation of phosphate homeostasis. I have helped to characterize the physiological role of fibroblast growth factor 23 in health and in chronic kidney disease, and the impact of elevated fibroblast growth factor 23 levels on adverse clinical outcomes in patients with kidney disease.

Education and Training

  • Research Fellowship in Nephrology, Massachusetts General Hospital, 2000 - 2001
  • Clinical Fellowship in Nephrology, Brigham and Women's Hospital, 1999 - 2000
  • Internal Medicine Residency, Massachusetts General Hospital, 1996 - 1999
  • M.Med.Sc., Harvard Medical School, 2002
  • M.D., State University of New York, Brooklyn, 1996


Thadhani, Ravi, Myles Wolf, Karen Hsu-Blatman, Laura Sandler, David Nathan, and Jeffrey L. Ecker. “First-trimester sex hormone binding globulin and subsequent gestational diabetes mellitus.” Am J Obstet Gynecol 189, no. 1 (July 2003): 171–76.

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Wolf, Myles, Laura Sandler, Karen Hsu, Karen Vossen-Smirnakis, Jeffrey L. Ecker, and Ravi Thadhani. “First-trimester C-reactive protein and subsequent gestational diabetes.” Diabetes Care 26, no. 3 (March 2003): 819–24.

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Wolf, Myles, Laura Sandler, Ricardo Jimenez-Kimble, Anand Shah, Jeffrey L. Ecker, and Ravi Thadhani. “Insulin resistance but not inflammation is associated with gestational hypertension.” Hypertension 40, no. 6 (December 2002): 886–91.

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Wolf, Myles, Laura Sandler, Kristine Muñoz, Karen Hsu, Jeffrey L. Ecker, and Ravi Thadhani. “First trimester insulin resistance and subsequent preeclampsia: a prospective study.” J Clin Endocrinol Metab 87, no. 4 (April 2002): 1563–68.

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Thadhani, Ravi, Myles Wolf, Michael L. West, Marcello Tonelli, Robin Ruthazer, Gregory M. Pastores, and Gregorio T. Obrador. “Patients with Fabry disease on dialysis in the United States.” Kidney Int 61, no. 1 (January 2002): 249–55.

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Wolf, M., E. Kettyle, L. Sandler, J. L. Ecker, J. Roberts, and R. Thadhani. “Obesity and preeclampsia: the potential role of inflammation.” Obstet Gynecol 98, no. 5 Pt 1 (November 2001): 757–62.

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