P. Murali Doraiswamy, MBBS

Professor of Psychiatry and Behavioral Sciences
Director, Neurocognitive Disorders Program
Professor in Medicine
Faculty Network Member of the Duke Institute for Brain Sciences
Affiliate of the Duke Initiative for Science & Society
Campus mail 3550 Hosp South, Durham, NC 27710

Murali Doraiswamy MBBS FRCP is professor of psychiatry and professor in medicine at the Duke University School of Medicine where he is a highly respected physician neuroscientist at the Duke Institute for Brain Sciences. He specializes in the areas of brain health and personalized medicine and leads a clinical trials unit in developing novel personal diagnostics and therapeutics for cognitive enhancement and mental well-being. Prof Doraiswamy has been an advisor to leading government agencies, businesses and advocacy groups. He has served as the chair of the World Economic Forum’s Global Agenda Council on Brain Research and lectured at leading global forums to advance the forefront of neuroscience research.  Moreover as co-author of a popular book The Alzheimer’s Action Plan and co-author on more than 350 publications, he has received several awards in recognition of his scientific work and his involvement in pivotal landmark trials that have helped develop many modern neurotherapeutics. Additionally, he is a leading advocate for increasing funding for brain and behavioral research to help address great looming challenges in society posed by modern developments in the 21st century. His research has been featured in media outlets such as BBC, The New York Times, Scientific American, The Wall Street Journal, National Public Radio, CBS Evening news, The Dr Oz Show, Oprah, and TIME. He has appeared in acclaimed documentaries such as (Dis)Honesty: The Truth about Lies and Mysteries of the Brain.

  

Education and Training

  • M.B.B.S., University of Madras (India), 1987

Grants

Publications

Privitera, Gregory J., Quentin W. King-Shepard, Kayla N. Cuifolo, and P Murali Doraiswamy. “Differential food intake and food choice by depression and body mass index levels following a mood manipulation in a buffet-style setting.” J Health Psychol 24, no. 2 (February 2019): 199–208. https://doi.org/10.1177/1359105316650508.

PMID
27206838
Full Text

Blumenthal, James A., Patrick J. Smith, Stephanie Mabe, Alan Hinderliter, Pao-Hwa Lin, Lawrence Liao, Kathleen A. Welsh-Bohmer, et al. “Lifestyle and neurocognition in older adults with cognitive impairments: A randomized trial.” Neurology 92, no. 3 (January 15, 2019): e212–23. https://doi.org/10.1212/WNL.0000000000006784.

PMID
30568005
Full Text

MahmoudianDehkordi, Siamak, Matthias Arnold, Kwangsik Nho, Shahzad Ahmad, Wei Jia, Guoxiang Xie, Gregory Louie, et al. “Altered bile acid profile associates with cognitive impairment in Alzheimer's disease-An emerging role for gut microbiome.” Alzheimers Dement 15, no. 1 (January 2019): 76–92. https://doi.org/10.1016/j.jalz.2018.07.217.

PMID
30337151
Full Text

Petrella, Jeffrey R., Wenrui Hao, Adithi Rao, and P Murali Doraiswamy. “Computational Causal Modeling of the Dynamic Biomarker Cascade in Alzheimer's Disease.” Comput Math Methods Med 2019 (2019): 6216530. https://doi.org/10.1155/2019/6216530.

PMID
30863455
Full Text

Smith, Patrick J., Stephanie Mabe, Andrew Sherwood, Michael A. Babyak, P Murali Doraiswamy, Kathleen A. Welsh-Bohmer, William Kraus, James Burke, Alan Hinderliter, and James A. Blumenthal. “Association Between Insulin Resistance, Plasma Leptin, and Neurocognition in Vascular Cognitive Impairment.” J Alzheimers Dis 71, no. 3 (2019): 921–29. https://doi.org/10.3233/JAD-190569.

PMID
31476159
Full Text

Tolbert, S., Y. Liu, C. Hellegers, J. R. Petrella, M. W. Weiner, T. Z. Wong, and P. Murali Doraiswamy. “Financial Management Skills in Aging, MCI and Dementia: Cross Sectional Relationship to 18F-Florbetapir PET Cortical β-amyloid Deposition.” J Prev Alzheimers Dis 6, no. 4 (2019): 274–82. https://doi.org/10.14283/jpad.2019.26.

PMID
31686100
Full Text

Sohn, Dongwha, Katie Shpanskaya, Joseph E. Lucas, Jeffrey R. Petrella, Andrew J. Saykin, Rudolph E. Tanzi, Nagiza F. Samatova, and P Murali Doraiswamy. “Sex Differences in Cognitive Decline in Subjects with High Likelihood of Mild Cognitive Impairment due to Alzheimer's disease.” Sci Rep 8, no. 1 (May 10, 2018): 7490. https://doi.org/10.1038/s41598-018-25377-w.

PMID
29748598
Full Text

Lu, Donghuan, Karteek Popuri, Gavin Weiguang Ding, Rakesh Balachandar, Mirza Faisal Beg, and Mirza Faisal Alzheimer’s Disease Neuroimaging Initiative. “Multimodal and Multiscale Deep Neural Networks for the Early Diagnosis of Alzheimer's Disease using structural MR and FDG-PET images.” Sci Rep 8, no. 1 (April 9, 2018): 5697. https://doi.org/10.1038/s41598-018-22871-z.

PMID
29632364
Full Text

Mills, Paul J., Christine Tara Peterson, Meredith A. Pung, Sheila Patel, Lizabeth Weiss, Kathleen L. Wilson, P Murali Doraiswamy, Jeffery A. Martin, Rudolph E. Tanzi, and Deepak Chopra. “Change in Sense of Nondual Awareness and Spiritual Awakening in Response to a Multidimensional Well-Being Program.” J Altern Complement Med 24, no. 4 (April 2018): 343–51. https://doi.org/10.1089/acm.2017.0160.

PMID
29216441
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Mahjoub, Ines, Mohamed Ali Mahjoub, Islem Rekik, and Islem Alzheimer’s Disease Neuroimaging Initiative. “Brain multiplexes reveal morphological connectional biomarkers fingerprinting late brain dementia states.” Sci Rep 8, no. 1 (March 7, 2018): 4103. https://doi.org/10.1038/s41598-018-21568-7.

PMID
29515158
Full Text

Pages