P. Murali Doraiswamy, MBBS

Professor of Psychiatry and Behavioral Sciences
Director, Neurocognitive Disorders Program
Professor in Medicine
Faculty Network Member of the Duke Institute for Brain Sciences
Affiliate of the Duke Initiative for Science & Society
Campus mail 3550 Hosp South, Durham, NC 27710

Murali Doraiswamy MBBS FRCP is professor of psychiatry and professor in medicine at the Duke University School of Medicine where he is a highly respected physician neuroscientist at the Duke Institute for Brain Sciences. He specializes in the areas of brain health and personalized medicine and leads a clinical trials unit in developing novel personal diagnostics and therapeutics for cognitive enhancement and mental well-being. Prof Doraiswamy has been an advisor to leading government agencies, businesses and advocacy groups. He has served as the chair of the World Economic Forum’s Global Agenda Council on Brain Research and lectured at leading global forums to advance the forefront of neuroscience research.  Moreover as co-author of a popular book The Alzheimer’s Action Plan and co-author on more than 350 publications, he has received several awards in recognition of his scientific work and his involvement in pivotal landmark trials that have helped develop many modern neurotherapeutics. Additionally, he is a leading advocate for increasing funding for brain and behavioral research to help address great looming challenges in society posed by modern developments in the 21st century. His research has been featured in media outlets such as BBC, The New York Times, Scientific American, The Wall Street Journal, National Public Radio, CBS Evening news, The Dr Oz Show, Oprah, and TIME. He has appeared in acclaimed documentaries such as (Dis)Honesty: The Truth about Lies and Mysteries of the Brain.

  

Education and Training

  • M.B.B.S., University of Madras (India), 1987

Grants

Publications

Padmanabhan, Kanchana, Katie Shpanskaya, Gonzalo Bello, P Murali Doraiswamy, and Nagiza F. Samatova. “Toward Personalized Network Biomarkers in Alzheimer's Disease: Computing Individualized Genomic and Protein Crosstalk Maps.” Front Aging Neurosci 9 (2017): 315. https://doi.org/10.3389/fnagi.2017.00315.

PMID
29085293
Full Text

Pontecorvo, Michael J., Andrew Siderowf, Bruno Dubois, P Murali Doraiswamy, Giovanni B. Frisoni, Michael Grundman, Flavio Nobili, et al. “Effectiveness of Florbetapir PET Imaging in Changing Patient Management.” Dement Geriatr Cogn Disord 44, no. 3–4 (2017): 129–43. https://doi.org/10.1159/000478007.

PMID
28787712
Full Text

Peterson, Christine Tara, Joseph Lucas, Lisa St John-Williams, J Will Thompson, M Arthur Moseley, Sheila Patel, Scott N. Peterson, et al. “Identification of Altered Metabolomic Profiles Following a Panchakarma-based Ayurvedic Intervention in Healthy Subjects: The Self-Directed Biological Transformation Initiative (SBTI).” Sci Rep 6 (September 9, 2016): 32609. https://doi.org/10.1038/srep32609.

PMID
27611967
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Mills, Paul J., Kathleen L. Wilson, Meredith A. Pung, Lizabeth Weiss, Sheila Patel, P Murali Doraiswamy, Christine Peterson, et al. “The Self-Directed Biological Transformation Initiative and Well-Being.” J Altern Complement Med 22, no. 8 (August 2016): 627–34. https://doi.org/10.1089/acm.2016.0002.

PMID
27351443
Full Text

Iturria-Medina, Y., R. C. Sotero, P. J. Toussaint, J. M. Mateos-Pérez, A. C. Evans, and A. C. Alzheimer’s Disease Neuroimaging Initiative. “Early role of vascular dysregulation on late-onset Alzheimer's disease based on multifactorial data-driven analysis.” Nat Commun 7 (June 21, 2016): 11934. https://doi.org/10.1038/ncomms11934.

PMID
27327500
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Risacher, Shannon L., Brenna C. McDonald, Eileen F. Tallman, John D. West, Martin R. Farlow, Fredrick W. Unverzagt, Sujuan Gao, et al. “Association Between Anticholinergic Medication Use and Cognition, Brain Metabolism, and Brain Atrophy in Cognitively Normal Older Adults.” Jama Neurol 73, no. 6 (June 1, 2016): 721–32. https://doi.org/10.1001/jamaneurol.2016.0580.

PMID
27088965
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Prescott, Jeffrey W., Arnaud Guidon, P Murali Doraiswamy, Kingshuk Roy Choudhury, Chunlei Liu, Jeffrey R. Petrella, and Jeffrey R. Alzheimer’s Disease Neuroimaging Initiative. “The Alzheimer Structural Connectome: Changes in Cortical Network Topology with Increased Amyloid Plaque Burden.” Radiology 279, no. 1 (April 2016): 328. https://doi.org/10.1148/radiol.2016164007.

PMID
26989936
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Hunsberger, Joshua G., Mahendra Rao, Joanne Kurtzberg, Jeff W. M. Bulte, Anthony Atala, Frank M. LaFerla, Henry T. Greely, et al. “Accelerating stem cell trials for Alzheimer's disease.” Lancet Neurol 15, no. 2 (February 2016): 219–30. https://doi.org/10.1016/S1474-4422(15)00332-4.

PMID
26704439
Full Text

Motter, Jeffrey N., Monique A. Pimontel, David Rindskopf, Davangere P. Devanand, P Murali Doraiswamy, and Joel R. Sneed. “Computerized cognitive training and functional recovery in major depressive disorder: A meta-analysis.” J Affect Disord 189 (January 1, 2016): 184–91. https://doi.org/10.1016/j.jad.2015.09.022.

PMID
26437233
Full Text

Pages