Pao-Hwa Lin, PhD

Associate Professor in Medicine
Member of Duke Molecular Physiology Institute
Member of the Duke Cancer Institute
Campus mail 3475 Erwin Road Suite 100, Stedman Nutrition Center, Durham, NC 27705
Phone (919) 660-6685
Email address lin00004@mc.duke.edu

My research interest lies generally in the area of dietary patterns and chronic diseases including hypertension using controlled feeding study and lifestyle intervention designs.

Two major controlled feeding clinical trials that I was involved in include the Dietary Approaches to Stop Hypertension (DASH) Study and the Dietary Approaches to Stop Hypertension-Sodium (DASH-Sodium) Study. In addition to being an active member for the diet committee for DASH, I also function as the chair of the diet committee for the DASH-Sodium study.  I am familiar with the development and operation of a controlled feeding study, which means the process of study design, development of questionnaire/forms for data collection/monitoring, development of quality assurance procedure, and data analysis.

I've also helped with the design and implementation of the lifestyle behavioral intervention program for the Hypertension Improvement Project (HIP), PREMIER clinical trial, Weight Loss Maintenance trial (WLM), ENCORE study, and the Cell Phone Intervention for You (CITY) trial.

Key words: Diet, controlled feeding study, mineral, blood pressure, nutrition.

Education and Training

  • Ph.D., University of Texas, Austin, 1990

Publications

Xie, Wuxiang, Yanfang Wang, Jianqin Sun, Guo Zeng, Huilian Zhu, Zhenquan Yang, Pei Gao, et al. “Protocol of a multicenter, single-blind, randomised, parallel controlled feeding trial evaluating the effect of a Chinese Healthy Heart (CHH) diet in lowering blood pressure and other cardiovascular risk factors.” Bmj Open 10, no. 8 (August 20, 2020): e036394. https://doi.org/10.1136/bmjopen-2019-036394.

PMID
32819944
Full Text

Chatterjee, Ranee, Clemontina A. Davenport, Lydia Kwee, David D’Alessio, Laura P. Svetkey, Pao-Hwa Lin, Cris A. Slentz, et al. “Preliminary evidence of effects of potassium chloride on a metabolomic path to diabetes and cardiovascular disease.” Metabolomics 16, no. 7 (June 18, 2020): 75. https://doi.org/10.1007/s11306-020-01696-w.

PMID
32556595
Full Text

Freedland, Stephen J., Jenifer Allen, Aubrey Jarman, Taofik Oyekunle, Andrew J. Armstrong, Judd W. Moul, Howard M. Sandler, et al. “A Randomized Controlled Trial of a 6-Month Low-Carbohydrate Intervention on Disease Progression in Men with Recurrent Prostate Cancer: Carbohydrate and Prostate Study 2 (CAPS2).” Clin Cancer Res 26, no. 12 (June 15, 2020): 3035–43. https://doi.org/10.1158/1078-0432.CCR-19-3873.

PMID
32108029
Full Text

Chi, Jen-Tsan, Pao-Hwa Lin, Vladimir Tolstikov, Taofik Oyekunle, Emily Y. Chen, Valerie Bussberg, Bennett Greenwood, et al. “Metabolomic effects of androgen deprivation therapy treatment for prostate cancer.” Cancer Med 9, no. 11 (June 2020): 3691–3702. https://doi.org/10.1002/cam4.3016.

PMID
32232974
Full Text

Blumenthal, James A., Patrick J. Smith, Stephanie Mabe, Alan Hinderliter, Kathleen Welsh-Bohmer, Jeffrey N. Browndyke, P Murali Doraiswamy, et al. “Longer Term Effects of Diet and Exercise on Neurocognition: 1-Year Follow-up of the ENLIGHTEN Trial.” J Am Geriatr Soc 68, no. 3 (March 2020): 559–68. https://doi.org/10.1111/jgs.16252.

PMID
31755550
Full Text

Barrett, Nadine J., Kearston L. Ingraham, Kenisha Bethea, Pao Hwa-Lin, Maritza Chirinos, Laura J. Fish, Schenita Randolph, et al. “Project PLACE: Enhancing community and academic partnerships to describe and address health disparities.,” 146:167–88, 2020. https://doi.org/10.1016/bs.acr.2020.01.009.

PMID
32241388
Full Text

Smith, Patrick J., Stephanie M. Mabe, Andrew Sherwood, P Murali Doraiswamy, Kathleen A. Welsh-Bohmer, James R. Burke, William E. Kraus, et al. “Metabolic and Neurocognitive Changes Following Lifestyle Modification: Examination of Biomarkers from the ENLIGHTEN Randomized Clinical Trial.” J Alzheimers Dis 77, no. 4 (2020): 1793–1803. https://doi.org/10.3233/JAD-200374.

PMID
32925039
Full Text

Vidal, Adriana C., Taofik Oyekunle, Lauren E. Howard, Nitin Shivappa, Amanda De Hoedt, Jane C. Figueiredo, Emanuela Taioli, et al. “Dietary inflammatory index (DII) and risk of prostate cancer in a case-control study among Black and White US Veteran men.” Prostate Cancer Prostatic Dis 22, no. 4 (December 2019): 580–87. https://doi.org/10.1038/s41391-019-0143-4.

PMID
30980026
Full Text

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