Rasheed Adebayo Gbadegesin, MBBS

Professor of Pediatrics
Wilburt C. Davison Distinguished Professor
Associate Dean for Physician-Scientist Development
Director of the Office of Physician-Science Development in the School of Medicine
Professor in Medicine
Affiliate of Duke Molecular Physiology Institute
Campus mail Box 3959 Med Ctr, Durham, NC 27710
Phone (919) 684-4246
Email address rasheed.gbadegesin@duke.edu

Molecular genetics of glomerular disease
Genetic risk factors for childhood onset idiopathic nephrotic syndrome

Education and Training

  • Pediatric Nephrology Fellow, Pediatrics, University of Michigan, Ann Arbor, 2004 - 2007
  • Pediatric Resident, Pediatrics, New York Presbyterian Hospital, 2002 - 2004
  • Pediatric Resident, Pediatrics, University of Ibadan, College of Medicine (Nigeria), 1989 - 1995
  • Medical Officer, National Service, University of Ibadan, College of Medicine (Nigeria), 1988 - 1989
  • Intern, Med/Surg/Peds/Ob Gyn, University of Ibadan, College of Medicine (Nigeria), 1987 - 1988
  • M.B.B.S., University of Ibadan, College of Medicine (Nigeria), 1987

Publications

Gbadegesin, Rasheed A., Peter J. Lavin, Gentzon Hall, Bartlomiej Bartkowiak, Alison Homstad, Ruiji Jiang, Guanghong Wu, et al. “Inverted formin 2 mutations with variable expression in patients with sporadic and hereditary focal and segmental glomerulosclerosis.” Kidney Int 81, no. 1 (January 2012): 94–99. https://doi.org/10.1038/ki.2011.297.

PMID
21866090
Full Text

Akilesh, Shreeram, Hani Suleiman, Haiyang Yu, M Christine Stander, Peter Lavin, Rasheed Gbadegesin, Corinne Antignac, et al. “Arhgap24 inactivates Rac1 in mouse podocytes, and a mutant form is associated with familial focal segmental glomerulosclerosis.” J Clin Invest 121, no. 10 (October 2011): 4127–37. https://doi.org/10.1172/JCI46458.

PMID
21911940
Full Text

Gbadegesin, Rasheed, Peter Lavin, John Foreman, and Michelle Winn. “Pathogenesis and therapy of focal segmental glomerulosclerosis: an update.” Pediatr Nephrol 26, no. 7 (July 2011): 1001–15. https://doi.org/10.1007/s00467-010-1692-x.

PMID
21110043
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Heeringa, Saskia F., Gil Chernin, Moumita Chaki, Weibin Zhou, Alexis J. Sloan, Ziming Ji, Letian X. Xie, et al. “COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness.” J Clin Invest 121, no. 5 (May 2011): 2013–24. https://doi.org/10.1172/JCI45693.

PMID
21540551
Full Text

Eckel, Jason, Peter J. Lavin, Elizabeth A. Finch, Nirvan Mukerji, Jarrett Burch, Rasheed Gbadegesin, Guanghong Wu, et al. “TRPC6 enhances angiotensin II-induced albuminuria.” J Am Soc Nephrol 22, no. 3 (March 2011): 526–35. https://doi.org/10.1681/ASN.2010050522.

PMID
21258036
Full Text

Gbadegesin, R. A., and M. P. Winn. “Novel Insertion-Deletion Mutation in Uromodulin in a Large Kindred with Familial CKD and Nephrotic Range Proteinuria.” Pediatric Nephrology 25, no. 9 (September 1, 2010): 1911–12.

Scholars@Duke

Gbadegesin, Rasheed, Peter Lavin, Louis Janssens, Bartlomiej Bartkowiak, Alison Homstad, Guanghong Wu, Brandy Bowling, et al. “A new locus for familial FSGS on chromosome 2p.” J Am Soc Nephrol 21, no. 8 (August 2010): 1390–97. https://doi.org/10.1681/ASN.2009101046.

PMID
20616172
Full Text

Gbadegesin, Rasheed, Shuang Zhao, John Charpie, Patrick D. Brophy, William E. Smoyer, and Jen-Jar Lin. “Significance of hemolysis on extracorporeal life support after cardiac surgery in children.” Pediatr Nephrol 24, no. 3 (March 2009): 589–95. https://doi.org/10.1007/s00467-008-1047-z.

PMID
19002722
Full Text

Gbadegesin, Rasheed, Bartlomiej Bartkowiak, Peter J. Lavin, Nirvan Mukerji, Guanghong Wu, Brandy Bowling, Jason Eckel, Tirupapuliyur Damodaran, and Michelle P. Winn. “Exclusion of homozygous PLCE1 (NPHS3) mutations in 69 families with idiopathic and hereditary FSGS.” Pediatr Nephrol 24, no. 2 (February 2009): 281–85. https://doi.org/10.1007/s00467-008-1025-5.

PMID
18975016
Full Text

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