Redford B. Williams, MD

Professor of Psychiatry and Behavioral Sciences
Professor of Psychology and Neuroscience
Professor of Medicine
Campus mail 905 W. Main Street, Suite 22 (2nd Floor), Durham, NC 27701
Phone (919) 684-3863
Email address redfordw@duke.edu

My research aims to identify psychosocial factors that are involved in the pathogenesis and course of major medical disorders, to characterize the biobehavioral mechanisms whereby such factors influence disease, and to develop both behavioral and pharmacologic means of preventing or ameliorating the adverse impact of psychosocial factors on health and disease. Specific projects that are currently active include: 1) The influence of hostile personality, social isolation, depression and other psychosocial risk factors upon the development and course of cardiometabolic disease; 2) Biological and genetic mechanisms whereby psychosocial risk factors influence disease development and course; and 3) Behavioral and pharmacologic approaches to ameliorate impact of psychosocial risk factors on disease risk and course.

Education and Training

  • M.D., Yale University, 1967

Publications

Samad, Zainab, Stephen Boyle, Amit N. Vora, Richard C. Becker, Thomas L. Ortel, Cynthia Kuhn, Redford B. Williams, et al. “Sex Differences in Platelet Reactivity, Cardiovascular and Psychological Response to Mental Stress in Patients With Known Coronary Artery Disease: Data From the Responses of Mental Stress Induced Myocardial Ischemia to Escitalopram Treatment Study.” In Circulation, Vol. 128. LIPPINCOTT WILLIAMS & WILKINS, 2013.

Scholars@Duke

Brummett, Beverly H., Michael A. Babyak, Abanish Singh, Rong Jiang, Redford B. Williams, Kathleen Mullan Harris, and Ilene C. Siegler. “Socioeconomic indices as independent correlates of C-reactive protein in the National Longitudinal Study of Adolescent Health.” Psychosom Med 75, no. 9 (November 2013): 882–93. https://doi.org/10.1097/PSY.0000000000000005.

PMID
24163384
Full Text

Boyle, Stephen H., Zainab Samad, Richard C. Becker, Redford Williams, Cynthia Kuhn, Thomas L. Ortel, Maragatha Kuchibhatla, et al. “Depressive symptoms and mental stress-induced myocardial ischemia in patients with coronary heart disease.” Psychosom Med 75, no. 9 (November 2013): 822–31. https://doi.org/10.1097/PSY.0b013e3182a893ae.

PMID
24163385
Full Text

Harris, Kathleen Mullan, Carolyn Tucker Halpern, Jon Hussey, Eric A. Whitsel, Ley Killeya-Jones, Joyce Tabor, Glen Elder, et al. “Social, behavioral, and genetic linkages from adolescence into adulthood.” Am J Public Health 103 Suppl 1 (October 2013): S25–32. https://doi.org/10.2105/AJPH.2012.301181.

PMID
23927505
Full Text

Proeschold-Bell, Rae Jean, Robin Swift, H Edgar Moore, Gary Bennett, Xiang-Fang Li, Rachel Blouin, Virginia P. Williams, Redford B. Williams, and David Toole. “Use of a randomized multiple baseline design: rationale and design of the spirited life holistic health intervention study.” Contemp Clin Trials 35, no. 2 (July 2013): 138–52. https://doi.org/10.1016/j.cct.2013.05.005.

PMID
23685205
Full Text

Jiang, Wei, Eric J. Velazquez, Maragatha Kuchibhatla, Zainab Samad, Stephen H. Boyle, Cynthia Kuhn, Richard C. Becker, et al. “Effect of escitalopram on mental stress-induced myocardial ischemia: results of the REMIT trial.” Jama 309, no. 20 (May 22, 2013): 2139–49. https://doi.org/10.1001/jama.2013.5566.

PMID
23695483
Full Text

Williams, Redford B., George D. Bishop, Brett C. Haberstick, Andrew Smolen, Michael J. Helms, Beverly H. Brummett, Ilene C. Siegler, et al. “POPULATION DIFFERENCES IN ASSOCIATIONS OF SEROTONIN TRANSPORTER PROMOTER POLYMORPHISM (5HTTLPR) DI- AND TRIALLELIC GENOTYPES WITH BLOOD PRESSURE AND HYPERTENSION PREVALENCE.” In Psychosomatic Medicine, 75:A64–A64. LIPPINCOTT WILLIAMS & WILKINS, 2013.

Scholars@Duke

Babyak, Michael A., Richard C. Becker, Michael J. Helms, Rong Jiang, Abanish Singh, Beverly H. Brummett, Ilene C. Siegler, Allison Ashley-Koch, Thomas Ortel, and Redford B. Williams. “ADRENERGIC GENE VARIANTS ARE ASSOCIATED WITH PLATELET AGGREGATION TO EPINEPHRINE.” In Psychosomatic Medicine, 75:A87–A87. LIPPINCOTT WILLIAMS & WILKINS, 2013.

Scholars@Duke

Lane, James D., Cynthia M. Kuhn, Richard S. Surwit, Ilene C. Siegler, Beverly H. Brummett, and Redford B. Williams. “BLOOD PRESSURE 'NON-DIPPING' STATUS IS ASSOCIATED WITH GREATER OVERNIGHT EPINEPHRINE EXCRETION.” In Psychosomatic Medicine, 75:A31–A31. LIPPINCOTT WILLIAMS & WILKINS, 2013.

Scholars@Duke

Georgiades, Anastasia, Beverly H. Brummett, Ilene C. Siegler, Richard S. Surwit, Cynthia Kuhn, Katherine Grichnik, Mark Stafford-Smith, and Redford B. Williams. “EFFECT OF CENTRAL NERVOUS SYSTEM SEROTONIN FUNCTION ON INFLAMMATION, ADIPOSITY AND INSULIN SENSITIVITY.” In Psychosomatic Medicine, 75:A69–A69. LIPPINCOTT WILLIAMS & WILKINS, 2013.

Scholars@Duke

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