Sana Mustapha Al-Khatib, MD

Professor of Medicine
Member in the Duke Clinical Research Institute
Campus mail 7521 N Pavilion Bldg, Durham, NC 27715
Phone (919) 668-8649
Email address alkha001@mc.duke.edu

Dr. Sana M. Al-Khatib is a tenured Professor of Medicine at Duke University Medical Center, a board-certified clinical electrophysiologist and an experienced clinical researcher in cardiac arrhythmias.  As a graduate of the NIH-funded Clinical Research Training Program, she is one of a few electrophysiologists nationwide with expertise in quantitative research methods. Her clinical expertise is in sudden cardiac death prevention, atrial fibrillation and ventricular arrhythmias, and implantable cardiac devices. Her research expertise lies in the design and conduct of clinical trials, outcomes research, and cost-effectiveness analyses. She is a recipient of a National Heart, Lung and Blood Institute’s R-01 grant titled “Implantable Cardioverter Defibrillator Therapy in Patients with Heart Failure” (2009-2013) and of an American Heart Association Career Development Award (2002-2006). She is a Co-Principal Investigator on an NHLBI-funded T-32 Postdoctoral Training in Cardiovascular Clinical Research and on several Agency of Healthcare Research and Quality sponsored R-01 grants including the “Duke Cardiovascular Center for Education and Research on Therapeutics.” She has more than 130 publications in peer-reviewed journals. She has established several collaborative research efforts both within and outside her institution. The goals of these collaborations are to synergize efforts aimed at improving the survival and quality of life of patients at risk for sudden cardiac death and those with atrial and ventricular arrhythmias through clinical trials and outcomes-based research and to evaluate study design and data analysis in order to improve the quality of research done in these arenas. Dr. Al-Khatib is an Associate Editor for the American Heart Journal and is on the Editorial Board for the Journal of Cardiovascular Electrophysiology. Dr. Al-Khatib serves on multiple national committees including the Heart Rhythm Society Board of Trustees, the Heart Rhythm Society Health Policy committee, the Heart Rhythm Society Legislative subcommittee, the Heart Rhythm Society Program Planning committee, the American College of Cardiology ICD Registry Steering committee, and the National Quality Forum Cardiovascular Steering committee.

In Their Words

Education and Training

  • Fellow in Cardiology, Medicine, Duke University, 1996 - 2000
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.D., American University of Beirut (Lebannon), 1993

Publications

Al-Khatib, SM, Lucas, FL, Jollis, JG, Malenka, DJ, and Wennberg, DE. "The relation between patients' outcomes and the volume of cardioverter-defibrillator implantation procedures performed by physicians treating Medicare beneficiaries." J Am Coll Cardiol 46, no. 8 (October 18, 2005): 1536-1540.

PMID
16226180
Full Text

Al-Khatib, SM, Sanders, GD, Mark, DB, Lee, KL, Bardy, GH, Bigger, JT, Buxton, AE, Connolly, S, Kadish, A, Moss, A, Feldman, AM, Ellenbogen, KA, Singh, S, Califf, RM, and Expert panel participating in a Duke Clinical Research Institute-sponsored conference, . "Implantable cardioverter defibrillators and cardiac resynchronization therapy in patients with left ventricular dysfunction: randomized trial evidence through 2004." American Heart Journal 149, no. 6 (June 2005): 1020-1034. (Review)

PMID
15976783
Full Text

Al-Khatib, SM, Allen LaPointe, NM, Kramer, JM, Chen, AY, Hammill, BG, Delong, L, and Califf, RM. "A survey of health care practitioners' knowledge of the QT interval." Journal of General Internal Medicine 20, no. 5 (May 2005): 392-396.

PMID
15963159
Full Text

Mark, DB, Nelson, CL, Anstrom, KJ, Al-Khatib, SM, Tsiatis, AA, Poole, J, Johnson, G, Anderson, J, Cowper, PA, Clapp-Channing, NE, Davidson-Ray, L, Lee, KL, Bardy, GH, and Investigators, S-H. "Cost-effectiveness of ICD therapy in the sudden cardiac death in heart failure trial (SCD-HeFT)." April 5, 2005.

Scholars@Duke

Meine, TJ, Al-Khatib, SM, Alexander, JH, Granger, CB, White, HD, Kilaru, R, Williams, K, Ohman, EM, Topol, E, and Califf, RM. "Incidence, predictors, and outcomes of high-degree atrioventricular block complicating acute myocardial infarction treated with thrombolytic therapy." American Heart Journal 149, no. 4 (April 2005): 670-674.

PMID
15990751
Full Text

Al-Khatib, SM, Anstrom, KJ, Eisenstein, EL, Peterson, ED, Jollis, JG, Mark, DB, Li, Y, O'Connor, CM, Shaw, LK, and Califf, RM. "Clinical and economic implications of the Multicenter Automatic Defibrillator Implantation Trial-II." Annals of Internal Medicine 142, no. 8 (April 2005): 593-600.

PMID
15838065
Full Text

Al-Khatib, SM, Goyal, A, Hafley, GE, Alexander, JH, Mack, MJ, Wolf, RK, Cohn, LH, Gennevois, D, Harrington, RA, Peterson, ED, Lee, KL, Califf, RM, Kouchoukos, NT, Ferguson, TB, and Invest, PREVENTIV. "Short-term outcomes of atrial fibrillation complicating coronary artery bypass graft surgery: Results from the PREVENT-IV trial." February 1, 2005.

Scholars@Duke

Al-Khatib, SM, Hafley, GE, Lee, KL, and Buxton, AE. "Predictors of appropriate implantable cardioverter defibrillator therapy in the multi-center unsustained tachycardia trial." October 26, 2004.

Scholars@Duke

Hayes, SN, Al-Khatib, SM, and De Marco, T. "Gender and utilization of device therapies: Insights from a retrospective national study." October 26, 2004.

Scholars@Duke

Al-Khatib, SM, Shaw, LK, Lee, KL, O'Connor, C, and Califf, RM. "Is rhythm control superior to rate control in patients with atrial fibrillation and congestive heart failure?." The American Journal of Cardiology 94, no. 6 (September 2004): 797-800.

PMID
15374794
Full Text

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