Sana Mustapha Al-Khatib, MD

Professor of Medicine
Member in the Duke Clinical Research Institute
Campus mail 7521 N Pavilion Bldg, Durham, NC 27715
Phone (919) 668-8649
Email address alkha001@duke.edu

Dr. Sana M. Al-Khatib is a tenured Professor of Medicine at Duke University Medical Center, a board-certified clinical electrophysiologist and an experienced clinical researcher in cardiac arrhythmias.  As a graduate of the NIH-funded Clinical Research Training Program, she is one of a few electrophysiologists nationwide with expertise in quantitative research methods. Her clinical expertise is in sudden cardiac death prevention, atrial fibrillation and ventricular arrhythmias, and implantable cardiac devices. Her research expertise lies in the design and conduct of clinical trials, outcomes research, and cost-effectiveness analyses. She is a recipient of a National Heart, Lung and Blood Institute’s R-01 grant titled “Implantable Cardioverter Defibrillator Therapy in Patients with Heart Failure” (2009-2013) and of an American Heart Association Career Development Award (2002-2006). She is a Co-Principal Investigator on an NHLBI-funded T-32 Postdoctoral Training in Cardiovascular Clinical Research and on several Agency of Healthcare Research and Quality sponsored R-01 grants including the “Duke Cardiovascular Center for Education and Research on Therapeutics.” She has more than 130 publications in peer-reviewed journals. She has established several collaborative research efforts both within and outside her institution. The goals of these collaborations are to synergize efforts aimed at improving the survival and quality of life of patients at risk for sudden cardiac death and those with atrial and ventricular arrhythmias through clinical trials and outcomes-based research and to evaluate study design and data analysis in order to improve the quality of research done in these arenas. Dr. Al-Khatib is an Associate Editor for the American Heart Journal and is on the Editorial Board for the Journal of Cardiovascular Electrophysiology. Dr. Al-Khatib serves on multiple national committees including the Heart Rhythm Society Board of Trustees, the Heart Rhythm Society Health Policy committee, the Heart Rhythm Society Legislative subcommittee, the Heart Rhythm Society Program Planning committee, the American College of Cardiology ICD Registry Steering committee, and the National Quality Forum Cardiovascular Steering committee.

In Their Words

Education and Training

  • Fellow in Cardiology, Medicine, Duke University, 1996 - 2000
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.D., American University of Beirut (Lebanon), 1993

Publications

Al-Khatib, Sana M., Linda K. Shaw, Christopher M. O’Connor, and Robert M. Califf. “Sudden Cardiac Death in Patients with Diastolic Heart Failure.” In Journal of Cardiac Failure, 12:S59–S59. Elsevier BV, 2006. https://doi.org/10.1016/j.cardfail.2006.06.206.

Full Text

Mark, Daniel B., Charlotte L. Nelson, Kevin J. Anstrom, Sana M. Al-Khatib, Anastasios A. Tsiatis, Patricia A. Cowper, Nancy E. Clapp-Channing, et al. “Cost-effectiveness of defibrillator therapy or amiodarone in chronic stable heart failure: results from the Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT).” Circulation 114, no. 2 (July 11, 2006): 135–42. https://doi.org/10.1161/CIRCULATIONAHA.105.581884.

PMID
16818817
Full Text

Atwater, B. D., R. N. Vest, W. R. Mazzei, R. H. Tuttle, S. M. Al-Khatib, E. Velazquez, K. L. Lee, and M. T. Roe. “Sudden cardiac death risk prediction is enhanced when clinical characteristics and left ventricular ejection fraction are evaluated together rather than relying on left ventricular ejection fraction alone.” In Journal of the American College of Cardiology, 47:339A-339A. ELSEVIER SCIENCE INC, 2006.

Scholars@Duke

Al-Khatib, S. M., F. L. Lucas, J. G. Jollis, D. J. Malenka, and D. E. Wennberg. “Erratum: The relation between patient's outcomes and the volume of cardioverter-defibrillator implantation procedures performed by physicians treating medicare beneficiaries (Journal of the American College of Cardiology (2005) 46 (1536-1540)).” Journal of the American College of Cardiology 46, no. 10 (November 15, 2005): 1964. https://doi.org/10.1016/j.jacc.2005.10.019.

Full Text

Al-Khatib, S. M., F. L. Lucas, J. G. Jollis, D. J. Malenka, and D. E. Wennberg. “The relation between patients' outcomes and the volume of cardioverter-defibrillator implantation procedures performed by physicians treating medicare beneficiaries (vol 46, pg 1536, 2005).” Journal of the American College of Cardiology 46, no. 10 (November 15, 2005): 1964–1964. https://doi.org/10.1016/j.jacc.205.10.019.

Full Text

Al-Khatib, Sana M., F Lee Lucas, James G. Jollis, David J. Malenka, and David E. Wennberg. “The relation between patients' outcomes and the volume of cardioverter-defibrillator implantation procedures performed by physicians treating Medicare beneficiaries.” J Am Coll Cardiol 46, no. 8 (October 18, 2005): 1536–40. https://doi.org/10.1016/j.jacc.2005.04.063.

PMID
16226180
Full Text

Al-Khatib, Sana M., Gillian D. Sanders, Daniel B. Mark, Kerry L. Lee, Gust H. Bardy, J Thomas Bigger, Alfred E. Buxton, et al. “Implantable cardioverter defibrillators and cardiac resynchronization therapy in patients with left ventricular dysfunction: randomized trial evidence through 2004.” Am Heart J 149, no. 6 (June 2005): 1020–34. https://doi.org/10.1016/j.ahj.2005.02.005.

PMID
15976783
Full Text

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