Sana Mustapha Al-Khatib, MD

Professor of Medicine
Member in the Duke Clinical Research Institute
Campus mail 7521 N Pavilion Bldg, Durham, NC 27715
Phone (919) 668-8649
Email address alkha001@mc.duke.edu

Dr. Sana M. Al-Khatib is a tenured Professor of Medicine at Duke University Medical Center, a board-certified clinical electrophysiologist and an experienced clinical researcher in cardiac arrhythmias.  As a graduate of the NIH-funded Clinical Research Training Program, she is one of a few electrophysiologists nationwide with expertise in quantitative research methods. Her clinical expertise is in sudden cardiac death prevention, atrial fibrillation and ventricular arrhythmias, and implantable cardiac devices. Her research expertise lies in the design and conduct of clinical trials, outcomes research, and cost-effectiveness analyses. She is a recipient of a National Heart, Lung and Blood Institute’s R-01 grant titled “Implantable Cardioverter Defibrillator Therapy in Patients with Heart Failure” (2009-2013) and of an American Heart Association Career Development Award (2002-2006). She is a Co-Principal Investigator on an NHLBI-funded T-32 Postdoctoral Training in Cardiovascular Clinical Research and on several Agency of Healthcare Research and Quality sponsored R-01 grants including the “Duke Cardiovascular Center for Education and Research on Therapeutics.” She has more than 130 publications in peer-reviewed journals. She has established several collaborative research efforts both within and outside her institution. The goals of these collaborations are to synergize efforts aimed at improving the survival and quality of life of patients at risk for sudden cardiac death and those with atrial and ventricular arrhythmias through clinical trials and outcomes-based research and to evaluate study design and data analysis in order to improve the quality of research done in these arenas. Dr. Al-Khatib is an Associate Editor for the American Heart Journal and is on the Editorial Board for the Journal of Cardiovascular Electrophysiology. Dr. Al-Khatib serves on multiple national committees including the Heart Rhythm Society Board of Trustees, the Heart Rhythm Society Health Policy committee, the Heart Rhythm Society Legislative subcommittee, the Heart Rhythm Society Program Planning committee, the American College of Cardiology ICD Registry Steering committee, and the National Quality Forum Cardiovascular Steering committee.

In Their Words

Education and Training

  • Fellow in Cardiology, Medicine, Duke University, 1996 - 2000
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.D., American University of Beirut (Lebannon), 1993

Publications

Pokorney, SD, Granger, CB, Bloom, D, Thomas, KL, Al-Khatib, SM, Anderson, J, Heflin, MT, and Granger, BB. "Provider Rather Than Patient Misperceptions Appear to be the Most Common Barriers to Oral Anticoagulation Use for Stroke Prevention in Atrial Fibrillation." November 11, 2016.

Scholars@Duke

Pokorney, SD, Granger, CB, Bloom, D, Thomas, KL, Al-Khatib, SM, Anderson, J, Heflin, MT, and Granger, BB. "Provider Rather Than Patient Misperceptions Appear to be the Most Common Barriers to Oral Anticoagulation Use for Stroke Prevention in Atrial Fibrillation." November 11, 2016.

Scholars@Duke

Hijazi, Z, Sharma, A, Andersson, U, Alexander, JH, Al-Khatib, SM, Hanna, M, Held, C, Hylek, EM, Lopes, RD, Siegbahn, A, Granger, CB, and Wallentin, L. "Biomarkers Predict Cause of Death More Accurately Than Clinical Variables in Patients With Atrial Fibrillation on Oral Anticoagulation Results From the ARISTOTLE Trial." November 11, 2016.

Scholars@Duke

Zeitler, EP, Al-Khatib, SM, Friedman, DJ, Han, JY, Bardy, GH, Bigger, JT, Buxton, AE, Moss, AJ, Lee, KL, Steinman, R, Dorian, P, Hallstrom, A, Cappato, R, Kadish, AH, Kudenchuk, PJ, Mark, DB, Inoue, LY, and Sanders, GD. "Predicting Appropriate Shocks In Patients With Heart Failure: Patient Level Meta-analysis From SCD-HeFT and Madit II." November 11, 2016.

Scholars@Duke

Friedman, DJ, Al-Khatib, SM, Zeitler, EP, Han, J, Bardy, GH, Bigger, JT, Buxton, AE, Moss, AJ, Lee, KL, Steinman, R, Dorian, P, Hallstrom, A, Cappato, R, Kadish, AH, Kudenchuk, PJ, Mark, DB, Inoue, LY, and Sanders, GD. "New York Heart Association Class and the Mortality Benefit From Primary Prevention Implantable Cardioverter Defibrillator Use: A Pooled Analysis of 4 Randomized Control Trials." November 11, 2016.

Scholars@Duke

Friedman, DJ, Parzynski, CS, Varosy, PD, Prutkin, JM, Patton, KK, Mithani, A, Russo, AM, Curtis, JP, and Al-Khatib, SM. "Trends and In-Hospital Outcomes Associated With Adoption of the Subcutaneous Implantable Cardioverter Defibrillator in the United States." Jama Cardiology 1, no. 8 (November 2016): 900-911.

PMID
27603935
Full Text

Levine, GN, Bates, ER, Bittl, JA, Brindis, RG, Fihn, SD, Fleisher, LA, Granger, CB, Lange, RA, Mack, MJ, Mauri, L, Mehran, R, Mukherjee, D, Newby, LK, O'Gara, PT, Sabatine, MS, Smith, PK, Smith, SC, Halperin, JL, Al-Khatib, SM, Birtcher, KK, Bozkurt, B, Cigarroa, JE, Curtis, LH, Gentile, F, Gidding, S, Hlatky, MA, Ikonomidis, JS, Joglar, JA, Pressler, SJ, and Wijeysundera, DN. "2016 ACC/AHA guideline focused update on duration of dual antiplatelet therapy in patients with coronary artery disease: A report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines." The Journal of Thoracic and Cardiovascular Surgery 152, no. 5 (November 2016): 1243-1275.

PMID
27751237
Full Text

Friedman, DJ, Bao, H, Spatz, ES, Curtis, JP, Daubert, JP, and Al-Khatib, SM. "Association Between a Prolonged PR Interval and Outcomes of Cardiac Resynchronization Therapy: A Report From the National Cardiovascular Data Registry." Circulation 134, no. 21 (November 2016): 1617-1628.

PMID
27760795
Full Text

Al-Khatib, SM, Friedman, P, and Ellenbogen, KA. "Defibrillators: Selecting the Right Device for the Right Patient." Circulation 134, no. 18 (November 2016): 1390-1404. (Review)

PMID
27799257
Full Text

Al-Khatib, SM, Belbase, S, Sauro, D, Brock, G, Brink, K, and Jackson, KP. "Inappropriate shocks in a patient with a subcutaneous implantable cardioverter-defibrillator." HeartRhythm case reports 2, no. 6 (November 2016): 478-483.

PMID
28491741
Full Text

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