Sana Mustapha Al-Khatib, MD

Professor of Medicine
Member in the Duke Clinical Research Institute
Campus mail 7521 N Pavilion Bldg, Durham, NC 27715
Phone (919) 668-8649
Email address alkha001@mc.duke.edu

Dr. Sana M. Al-Khatib is a tenured Professor of Medicine at Duke University Medical Center, a board-certified clinical electrophysiologist and an experienced clinical researcher in cardiac arrhythmias.  As a graduate of the NIH-funded Clinical Research Training Program, she is one of a few electrophysiologists nationwide with expertise in quantitative research methods. Her clinical expertise is in sudden cardiac death prevention, atrial fibrillation and ventricular arrhythmias, and implantable cardiac devices. Her research expertise lies in the design and conduct of clinical trials, outcomes research, and cost-effectiveness analyses. She is a recipient of a National Heart, Lung and Blood Institute’s R-01 grant titled “Implantable Cardioverter Defibrillator Therapy in Patients with Heart Failure” (2009-2013) and of an American Heart Association Career Development Award (2002-2006). She is a Co-Principal Investigator on an NHLBI-funded T-32 Postdoctoral Training in Cardiovascular Clinical Research and on several Agency of Healthcare Research and Quality sponsored R-01 grants including the “Duke Cardiovascular Center for Education and Research on Therapeutics.” She has more than 130 publications in peer-reviewed journals. She has established several collaborative research efforts both within and outside her institution. The goals of these collaborations are to synergize efforts aimed at improving the survival and quality of life of patients at risk for sudden cardiac death and those with atrial and ventricular arrhythmias through clinical trials and outcomes-based research and to evaluate study design and data analysis in order to improve the quality of research done in these arenas. Dr. Al-Khatib is an Associate Editor for the American Heart Journal and is on the Editorial Board for the Journal of Cardiovascular Electrophysiology. Dr. Al-Khatib serves on multiple national committees including the Heart Rhythm Society Board of Trustees, the Heart Rhythm Society Health Policy committee, the Heart Rhythm Society Legislative subcommittee, the Heart Rhythm Society Program Planning committee, the American College of Cardiology ICD Registry Steering committee, and the National Quality Forum Cardiovascular Steering committee.

In Their Words

Education and Training

  • Fellow in Cardiology, Medicine, Duke University, 1996 - 2000
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.D., American University of Beirut (Lebannon), 1993

Publications

Zeitler, EP, Hellkamp, AS, Schulte, PJ, Fonarow, GC, Hernandez, AF, Peterson, ED, Sanders, GD, Yancy, CW, and Al-Khatib, SM. "Response to Letter Regarding Article, "Comparative Effectiveness of Implantable Cardioverter Defibrillators for Primary Prevention in Women"." Circulation. Heart Failure 9, no. 5 (May 2016). (Letter)

PMID
27162231
Full Text

Page, RL, Joglar, JA, Caldwell, MA, Calkins, H, Conti, JB, Deal, BJ, Estes, NAM, Field, ME, Goldberger, ZD, Hammill, SC, Indik, JH, Lindsay, BD, Olshansky, B, Russo, AM, Shen, W-K, Tracy, CM, and Al-Khatib, SM. "2015 ACC/AHA/HRS Guideline for the Management of Adult Patients With Supraventricular Tachycardia: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society." Journal of the American College of Cardiology 67, no. 13 (April 2016): e27-e115.

PMID
26409259
Full Text

Halperin, JL, Levine, GN, Al-Khatib, SM, Birtcher, KK, Bozkurt, B, Brindis, RG, Cigarroa, JE, Curtis, LH, Fleisher, LA, Gentile, F, Gidding, S, Hlatky, MA, Ikonomidis, J, Joglar, J, Pressler, SJ, and Wijeysundera, DN. "Further Evolution of the ACC/AHA Clinical Practice Guideline Recommendation Classification System: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines." Journal of the American College of Cardiology 67, no. 13 (April 2016): 1572-1574.

PMID
26409257
Full Text

Page, RL, Joglar, JA, Caldwell, MA, Calkins, H, Conti, JB, Deal, BJ, Estes, NAM, Field, ME, Goldberger, ZD, Hammill, SC, Indik, JH, Lindsay, BD, Olshansky, B, Russo, AM, Shen, W-K, Tracy, CM, and Al-Khatib, SM. "2015 ACC/AHA/HRS Guideline for the Management of Adult Patients With Supraventricular Tachycardia: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society." Journal of the American College of Cardiology 67, no. 13 (April 2016): 1575-1623.

PMID
26409258
Full Text

Al-Khatib, SM, Arshad, A, Balk, EM, Das, SR, Hsu, JC, Joglar, JA, and Page, RL. "Risk stratification for arrhythmic events in patients with asymptomatic pre-excitation: A systematic review for the 2015 ACC/AHA/HRS guideline for the management of adult patients with supraventricular tachycardia: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society." Heart rhythm 13, no. 4 (April 2016): e222-e237. (Review)

PMID
26409096
Full Text

Al-Khatib, SM. "The Risk of Sudden Cardiac Death in Mitral Valve Prolapse: Are All Patients Created Equal?." Journal of cardiovascular electrophysiology 27, no. 4 (April 2016): 469-470.

PMID
26756418
Full Text

Page, RL, Joglar, JA, Caldwell, MA, Calkins, H, Conti, JB, Deal, BJ, Estes, NAM, Field, ME, Goldberger, ZD, Hammill, SC, Indik, JH, Lindsay, BD, Olshansky, B, Russo, AM, Shen, W-K, Tracy, CM, and Al-Khatib, SM. "2015 ACC/AHA/HRS guideline for the management of adult patients with supraventricular tachycardia: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society." Heart rhythm 13, no. 4 (April 2016): e136-e221.

PMID
26409100
Full Text

Page, RL, Joglar, JA, Caldwell, MA, Calkins, H, Conti, JB, Deal, BJ, Estes, NAM, Field, ME, Goldberger, ZD, Hammill, SC, Indik, JH, Lindsay, BD, Olshansky, B, Russo, AM, Shen, W-K, Tracy, CM, and Al-Khatib, SM. "2015 ACC/AHA/HRS guideline for the management of adult patients with supraventricular tachycardia: Executive summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society." Heart rhythm 13, no. 4 (April 2016): e92-135.

PMID
26409097
Full Text

Hiratzka, LF, Creager, MA, Isselbacher, EM, Svensson, LG, Nishimura, RA, Bonow, RO, Guyton, RA, and Sundt, TM. "Surgery for aortic dilatation in patients with bicuspid aortic valves." The Journal of Thoracic and Cardiovascular Surgery 151, no. 4 (April 2016): 959-966.

Full Text

Hess, PL, Wojdyla, DM, Al-Khatib, SM, Lokhnygina, Y, Wallentin, L, Armstrong, PW, Roe, MT, Ohman, EM, Harrington, RA, Alexander, JH, White, HD, Van de Werf, F, Piccini, JP, Held, C, Aylward, PE, Moliterno, DJ, Mahaffey, KW, and Tricoci, P. "Sudden Cardiac Death After Non-ST-Segment Elevation Acute Coronary Syndrome." Jama Cardiology 1, no. 1 (April 2016): 73-79.

PMID
27437658
Full Text

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