Sana Mustapha Al-Khatib, MD

Professor of Medicine
Member in the Duke Clinical Research Institute
Campus mail 7521 N Pavilion Bldg, Durham, NC 27715
Phone (919) 668-8649
Email address alkha001@mc.duke.edu

Dr. Sana M. Al-Khatib is a tenured Professor of Medicine at Duke University Medical Center, a board-certified clinical electrophysiologist and an experienced clinical researcher in cardiac arrhythmias.  As a graduate of the NIH-funded Clinical Research Training Program, she is one of a few electrophysiologists nationwide with expertise in quantitative research methods. Her clinical expertise is in sudden cardiac death prevention, atrial fibrillation and ventricular arrhythmias, and implantable cardiac devices. Her research expertise lies in the design and conduct of clinical trials, outcomes research, and cost-effectiveness analyses. She is a recipient of a National Heart, Lung and Blood Institute’s R-01 grant titled “Implantable Cardioverter Defibrillator Therapy in Patients with Heart Failure” (2009-2013) and of an American Heart Association Career Development Award (2002-2006). She is a Co-Principal Investigator on an NHLBI-funded T-32 Postdoctoral Training in Cardiovascular Clinical Research and on several Agency of Healthcare Research and Quality sponsored R-01 grants including the “Duke Cardiovascular Center for Education and Research on Therapeutics.” She has more than 130 publications in peer-reviewed journals. She has established several collaborative research efforts both within and outside her institution. The goals of these collaborations are to synergize efforts aimed at improving the survival and quality of life of patients at risk for sudden cardiac death and those with atrial and ventricular arrhythmias through clinical trials and outcomes-based research and to evaluate study design and data analysis in order to improve the quality of research done in these arenas. Dr. Al-Khatib is an Associate Editor for the American Heart Journal and is on the Editorial Board for the Journal of Cardiovascular Electrophysiology. Dr. Al-Khatib serves on multiple national committees including the Heart Rhythm Society Board of Trustees, the Heart Rhythm Society Health Policy committee, the Heart Rhythm Society Legislative subcommittee, the Heart Rhythm Society Program Planning committee, the American College of Cardiology ICD Registry Steering committee, and the National Quality Forum Cardiovascular Steering committee.

In Their Words

Education and Training

  • Fellow in Cardiology, Medicine, Duke University, 1996 - 2000
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.D., American University of Beirut (Lebannon), 1993

Publications

Shen, Win-Kuang, Robert S. Sheldon, David G. Benditt, Mitchell I. Cohen, Daniel E. Forman, Zachary D. Goldberger, Blair P. Grubb, et al. “2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society..” J Am Coll Cardiol 70, no. 5 (August 1, 2017): 620–63. https://doi.org/10.1016/j.jacc.2017.03.002.

PMID
28286222
Full Text

Nishimura, Rick A., Catherine M. Otto, Robert O. Bonow, Blase A. Carabello, John P. Erwin, Lee A. Fleisher, Hani Jneid, et al. “2017 AHA/ACC Focused Update of the 2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines..” J Am Coll Cardiol 70, no. 2 (July 11, 2017): 252–89. https://doi.org/10.1016/j.jacc.2017.03.011.

PMID
28315732
Full Text

Randolph, Tiffany C., Anne S. Hellkamp, Emily P. Zeitler, Gregg C. Fonarow, Adrian F. Hernandez, Kevin L. Thomas, Eric D. Peterson, Clyde W. Yancy, and Sana M. Al-Khatib. “Utilization of cardiac resynchronization therapy in eligible patients hospitalized for heart failure and its association with patient outcomes..” In Am Heart J, 189:48–58, 2017. https://doi.org/10.1016/j.ahj.2017.04.001.

PMID
28625381
Full Text

Lopes, Renato D., Patrícia O. Guimarães, Bradley J. Kolls, Daniel M. Wojdyla, Cheryl D. Bushnell, Michael Hanna, J Donald Easton, et al. “Intracranial hemorrhage in patients with atrial fibrillation receiving anticoagulation therapy..” Blood 129, no. 22 (June 1, 2017): 2980–87. https://doi.org/10.1182/blood-2016-08-731638.

PMID
28356246
Full Text

Al-Khatib, Sana M., Gregg C. Fonarow, Jose A. Joglar, Lurdes Y. T. Inoue, Daniel B. Mark, Kerry L. Lee, Alan Kadish, Gust Bardy, and Gillian D. Sanders. “Primary Prevention Implantable Cardioverter Defibrillators in Patients With Nonischemic Cardiomyopathy: A Meta-analysis..” Jama Cardiol 2, no. 6 (June 1, 2017): 685–88. https://doi.org/10.1001/jamacardio.2017.0630.

PMID
28355432
Full Text

Pokorney, Sean D., Craig S. Parzynski, James P. Daubert, Donald D. Hegland, Paul D. Varosy, Jeptha P. Curtis, and Sana M. Al-Khatib. “Temporal Trends in and Factors Associated With Use of Single- Versus Dual-Coil Implantable Cardioverter-Defibrillator Leads: Data From the NCDR ICD Registry..” Jacc Clin Electrophysiol 3, no. 6 (June 2017): 612–19. https://doi.org/10.1016/j.jacep.2016.11.014.

PMID
29759435
Full Text

Zeitler, Emily P., Daniel J. Friedman, James P. Daubert, Sana M. Al-Khatib, Scott D. Solomon, Yitschak Biton, Scott McNitt, Wojciech Zareba, Arthur J. Moss, and Valentina Kutyifa. “Multiple Comorbidities and Response to Cardiac Resynchronization Therapy: MADIT-CRT Long-Term Follow-Up..” J Am Coll Cardiol 69, no. 19 (May 16, 2017): 2369–79. https://doi.org/10.1016/j.jacc.2017.03.531.

PMID
28494974
Full Text

Cowper, Patricia A., Shubin Sheng, Renato D. Lopes, Kevin J. Anstrom, Judith A. Stafford, Linda Davidson-Ray, Sana M. Al-Khatib, et al. “Economic Analysis of Apixaban Therapy for Patients With Atrial Fibrillation From a US Perspective: Results From the ARISTOTLE Randomized Clinical Trial..” Jama Cardiol 2, no. 5 (May 1, 2017): 525–34. https://doi.org/10.1001/jamacardio.2017.0065.

PMID
28355434
Full Text

Pokorney, Sean D., Xiaojuan Mi, Bradley G. Hammill, Nancy M. Allen LaPointe, Lesley H. Curtis, and Sana M. Al-Khatib. “Use of Antiarrhythmic Medications in Medicare Part D Patients With an Implantable Cardioverter-Defibrillator and Ventricular Tachycardia..” Am J Cardiol 119, no. 9 (May 1, 2017): 1401–6. https://doi.org/10.1016/j.amjcard.2017.01.030.

PMID
28341360
Full Text

Rao, Meena P., Sana M. Al-Khatib, Sean D. Pokorney, Lilin She, Alexander Romanov, Jose C. Nicolau, Kerry L. Lee, et al. “Sudden Cardiac Death in Patients With Ischemic Heart Failure Undergoing Coronary Artery Bypass Grafting: Results From the STICH Randomized Clinical Trial (Surgical Treatment for Ischemic Heart Failure)..” Circulation 135, no. 12 (March 21, 2017): 1136–44. https://doi.org/10.1161/CIRCULATIONAHA.116.026075.

PMID
28154006
Full Text

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