Sana Mustapha Al-Khatib, MD

Professor of Medicine
Member in the Duke Clinical Research Institute
Campus mail 7521 N Pavilion Bldg, Durham, NC 27715
Phone (919) 668-8649
Email address alkha001@mc.duke.edu

Dr. Sana M. Al-Khatib is a tenured Professor of Medicine at Duke University Medical Center, a board-certified clinical electrophysiologist and an experienced clinical researcher in cardiac arrhythmias.  As a graduate of the NIH-funded Clinical Research Training Program, she is one of a few electrophysiologists nationwide with expertise in quantitative research methods. Her clinical expertise is in sudden cardiac death prevention, atrial fibrillation and ventricular arrhythmias, and implantable cardiac devices. Her research expertise lies in the design and conduct of clinical trials, outcomes research, and cost-effectiveness analyses. She is a recipient of a National Heart, Lung and Blood Institute’s R-01 grant titled “Implantable Cardioverter Defibrillator Therapy in Patients with Heart Failure” (2009-2013) and of an American Heart Association Career Development Award (2002-2006). She is a Co-Principal Investigator on an NHLBI-funded T-32 Postdoctoral Training in Cardiovascular Clinical Research and on several Agency of Healthcare Research and Quality sponsored R-01 grants including the “Duke Cardiovascular Center for Education and Research on Therapeutics.” She has more than 130 publications in peer-reviewed journals. She has established several collaborative research efforts both within and outside her institution. The goals of these collaborations are to synergize efforts aimed at improving the survival and quality of life of patients at risk for sudden cardiac death and those with atrial and ventricular arrhythmias through clinical trials and outcomes-based research and to evaluate study design and data analysis in order to improve the quality of research done in these arenas. Dr. Al-Khatib is an Associate Editor for the American Heart Journal and is on the Editorial Board for the Journal of Cardiovascular Electrophysiology. Dr. Al-Khatib serves on multiple national committees including the Heart Rhythm Society Board of Trustees, the Heart Rhythm Society Health Policy committee, the Heart Rhythm Society Legislative subcommittee, the Heart Rhythm Society Program Planning committee, the American College of Cardiology ICD Registry Steering committee, and the National Quality Forum Cardiovascular Steering committee.

In Their Words

Education and Training

  • Fellow in Cardiology, Medicine, Duke University, 1996 - 2000
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.D., American University of Beirut (Lebannon), 1993

Publications

Pokorney, SD, Radder, C, Schulte, PJ, Al-Khatib, SM, Tricocci, P, Van de Werf, F, James, SK, Cannon, CP, Armstrong, PW, White, HD, Califf, RM, Gibson, CM, Giugliano, RP, Wallentin, L, Mahaffey, KW, Harrington, RA, Newby, LK, and Piccini, JP. "High-degree atrioventricular block, asystole, and electro-mechanical dissociation complicating non-ST-segment elevation myocardial infarction." American heart journal 171, no. 1 (January 2016): 25-32.

PMID
26699597
Full Text

Zeitler, EP, Hellkamp, AS, Schulte, PJ, Fonarow, GC, Hernandez, AF, Peterson, ED, Sanders, GD, Yancy, CW, and Al-Khatib, SM. "Comparative Effectiveness of Implantable Cardioverter Defibrillators for Primary Prevention in Women." Circulation. Heart failure 9, no. 1 (January 2016): e002630-.

PMID
26758365
Full Text

Zeitler, EP, Al-Khatib, SM, Jr, DJP, Kessler, LG, Kirtane, AJ, Kong, DF, Laschinger, J, Marinac-Dabic, D, Morice, M-C, Reed, T, Sedrakyan, A, Stein, KM, Tcheng, J, and Krucoff, MW. "Predictable and Su Stainable Implementation of National Cardiovascular Registries (PASSION) infrastructure: A think tank report from Medical Device Epidemiological Network Initiative (MDEpiNet)." AMERICAN HEART JOURNAL 171, no. 1 (January 2016): 64-72.

Full Text

Al-Khatib, SM, Gierisch, JM, Crowley, MJ, Coeytaux, RR, Myers, ER, Kendrick, A, and Sanders, GD. "Future Research Prioritization: Implantable Cardioverter-Defibrillator Therapy in Older Patients." Journal of general internal medicine 30, no. 12 (December 2015): 1812-1820.

PMID
26014894
Full Text

Al-Khatib, SM. "Primary prevention implantable cardioverter defibrillators are effective in preventing overall mortality in older patients." Evidence-based medicine 20, no. 6 (December 2015): 217-.

PMID
26395979
Full Text

Vinereanu, D, Stevens, SR, Alexander, JH, Al-Khatib, SM, Avezum, A, Bahit, MC, Granger, CB, Lopes, RD, Halvorsen, S, Hanna, M, Husted, S, Hylek, EM, Mărgulescu, AD, Wallentin, L, and Atar, D. "Clinical outcomes in patients with atrial fibrillation according to sex during anticoagulation with apixaban or warfarin: a secondary analysis of a randomized controlled trial." European heart journal 36, no. 46 (December 2015): 3268-3275.

PMID
26371113
Full Text

Friedman, DJ, Singh, JP, Curtis, JP, Tang, WHW, Bao, H, Spatz, ES, Hernandez, AF, Patel, UD, and Al-Khatib, SM. "Comparative Effectiveness of CRT-D Versus Defibrillator Alone in HF Patients With Moderate-to-Severe Chronic Kidney Disease." Journal of the American College of Cardiology 66, no. 23 (December 2015): 2618-2629.

PMID
26670062
Full Text

Zeitler, EP, Wang, Y, Dharmarajan, K, Anstrom, KJ, Peterson, ED, Daubert, JP, Curtis, JP, and Al-Khatib, SM. "Outcomes Associated With Lead Abandonment versus Lead Extraction Strategies for Revision of Sterile Leads: An NCDRO (R) Analysis." November 10, 2015.

Scholars@Duke

Al-Khatib, SM. "Assessing the appropriateness of ICD use "appropriately"." Heart rhythm 12, no. 10 (October 2015): 2094-2095.

PMID
26054309
Full Text

Smalley, JB, Merritt, MW, Al-Khatib, SM, McCall, D, Staman, KL, and Stepnowsky, C. "Ethical responsibilities toward indirect and collateral participants in pragmatic clinical trials." Clinical trials (London, England) 12, no. 5 (October 2015): 476-484.

PMID
26374687
Full Text

Pages