Hematologic Malignancies and Cellular Therapy

Sandeep S. Dave, MD

Professor of Medicine
Member of the Duke Cancer Institute
Campus mail 101 Science Drive, CIEMAS 2177c, Box 3382, Durham, NC 27710
Phone (919) 681-1922
Email address sandeep.dave@duke.edu

Education and Training

  • Fellow in Hematology-Oncology, Medicine, National Institutes of Health, 2001 - 2007
  • Medical Resident, Medicine, Northwestern University, 1999 - 2001
  • M.D., Northwestern University, 1999

Grants

Publications

Roy, S, Moore, AJ, Love, C, Reddy, A, Rajagopalan, D, Dave, SS, Li, L, Murre, C, and Zhuang, Y. "Id Proteins Suppress E2A-Driven Invariant Natural Killer T Cell Development prior to TCR Selection." Frontiers in Immunology 9 (January 24, 2018): 42-.

PMID
29416542
Full Text

Grossman, L, Chang, C, Dai, J, Nikitin, PA, Jima, DD, Dave, SS, and Luftig, MA. "Epstein-Barr Virus Induces Adhesion Receptor CD226 (DNAM-1) Expression during Primary B-Cell Transformation into Lymphoblastoid Cell Lines." mSphere 2, no. 6 (November 29, 2017).

PMID
29202043
Full Text

Bouska, A, Bi, C, Lone, W, Zhang, W, Kedwaii, A, Heavican, T, Lachel, CM, Yu, J, Ferro, R, Eldorghamy, N, Greiner, TC, Vose, J, Weisenburger, DD, Gascoyne, RD, Rosenwald, A, Ott, G, Campo, E, Rimsza, LM, Jaffe, ES, Braziel, RM, Siebert, R, Miles, RR, Dave, S, Reddy, A, Delabie, J, Staudt, LM, Song, JY, McKeithan, TW, Fu, K, Green, M, Chan, WC, and Iqbal, J. "Adult high-grade B-cell lymphoma with Burkitt lymphoma signature: genomic features and potential therapeutic targets." Blood 130, no. 16 (October 2017): 1819-1831.

PMID
28801451
Full Text

Reddy, A, Zhang, J, Davis, NS, Moffitt, AB, Love, CL, Waldrop, A, Leppa, S, Pasanen, A, Meriranta, L, Karjalainen-Lindsberg, M-L, Nørgaard, P, Pedersen, M, Gang, AO, Høgdall, E, Heavican, TB, Lone, W, Iqbal, J, Qin, Q, Li, G, Kim, SY, Healy, J, Richards, KL, Fedoriw, Y, Bernal-Mizrachi, L, Koff, JL, Staton, AD, Flowers, CR, Paltiel, O, Goldschmidt, N, Calaminici, M, Clear, A, Gribben, J, Nguyen, E, Czader, MB, Ondrejka, SL, Collie, A, Hsi, ED, Tse, E, Au-Yeung, RKH, Kwong, Y-L, and Srivastava, G et al. "Genetic and Functional Drivers of Diffuse Large B Cell Lymphoma." Cell 171, no. 2 (October 2017): 481-494.e15.

PMID
28985567
Full Text

Huang, J, Chen, M, Whitley, MJ, Kuo, H-C, Xu, ES, Walens, A, Mowery, YM, Van Mater, D, Eward, WC, Cardona, DM, Luo, L, Ma, Y, Lopez, OM, Nelson, CE, Robinson-Hamm, JN, Reddy, A, Dave, SS, Gersbach, CA, Dodd, RD, and Kirsch, DG. "Generation and comparison of CRISPR-Cas9 and Cre-mediated genetically engineered mouse models of sarcoma." Nature communications 8 (July 10, 2017): 15999-.

PMID
28691711
Full Text

Guo, X, Koff, JL, Moffitt, AB, Cinar, M, Ramachandiran, S, Chen, Z, Switchenko, JM, Mosunjac, M, Neill, SG, Mann, KP, Bagirov, M, Du, Y, Natkunam, Y, Khoury, HJ, Rossi, MR, Harris, W, Flowers, CR, Lossos, IS, Boise, LH, Dave, SS, Kowalski, J, and Bernal-Mizrachi, L. "Molecular impact of selective NFKB1 and NFKB2 signaling on DLBCL phenotype." Oncogene 36, no. 29 (July 2017): 4224-4232.

PMID
28368397
Full Text

Bouchlaka, MN, Moffitt, AB, Kim, J, Kink, JA, Bloom, DD, Love, C, Dave, S, Hematti, P, and Capitini, CM. "Human Mesenchymal Stem Cell-Educated Macrophages Are a Distinct High IL-6-Producing Subset that Confer Protection in Graft-versus-Host-Disease and Radiation Injury Models." Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 23, no. 6 (June 2017): 897-905.

PMID
28257800
Full Text

Moffitt, AB, Ondrejka, SL, McKinney, M, Rempel, RE, Goodlad, JR, Teh, CH, Leppa, S, Mannisto, S, Kovanen, PE, Tse, E, Au-Yeung, RKH, Kwong, Y-L, Srivastava, G, Iqbal, J, Yu, J, Naresh, K, Villa, D, Gascoyne, RD, Said, J, Czader, MB, Chadburn, A, Richards, KL, Rajagopalan, D, Davis, NS, Smith, EC, Palus, BC, Tzeng, TJ, Healy, JA, Lugar, PL, Datta, J, Love, C, Levy, S, Dunson, DB, Zhuang, Y, Hsi, ED, and Dave, SS. "Enteropathy-associated T cell lymphoma subtypes are characterized by loss of function of SETD2." The Journal of experimental medicine 214, no. 5 (May 2017): 1371-1386.

PMID
28424246
Full Text

McKinney, M, Moffitt, AB, Gaulard, P, Travert, M, De Leval, L, Nicolae, A, Raffeld, M, Jaffe, ES, Pittaluga, S, Xi, L, Heavican, T, Iqbal, J, Belhadj, K, Delfau-Larue, MH, Fataccioli, V, Czader, MB, Lossos, IS, Chapman-Fredricks, JR, Richards, KL, Fedoriw, Y, Ondrejka, SL, Hsi, ED, Low, L, Weisenburger, D, Chan, WC, Mehta-Shah, N, Horwitz, S, Bernal-Mizrachi, L, Flowers, CR, Beaven, AW, Parihar, M, Baseggio, L, Parrens, M, Moreau, A, Sujobert, P, Pilichowska, M, Evens, AM, and Chadburn, A et al. "The Genetic Basis of Hepatosplenic T-cell Lymphoma." Cancer discovery 7, no. 4 (April 2017): 369-379.

PMID
28122867
Full Text

Li, J, Roy, S, Kim, Y-M, Li, S, Zhang, B, Love, C, Reddy, A, Rajagopalan, D, Dave, S, Diehl, AM, and Zhuang, Y. "Id2 Collaborates with Id3 To Suppress Invariant NKT and Innate-like Tumors." Journal of immunology (Baltimore, Md. : 1950) 198, no. 8 (April 2017): 3136-3148.

PMID
28258199
Full Text

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