Scott Michael Palmer, MD

Professor of Medicine
Member in the Duke Clinical Research Institute
Vice-Chair for Research in the Department of Medicine
Professor in Immunology
Core Faculty in Innovation & Entrepreneurship
Campus mail 2085 Msrb2 2 Genome Ct, Durham, NC 27710
Phone (919) 684-0245
Email address scott.palmer@duke.edu

Dr. Palmer leads a successful program of clinical, basic and translational research in transplantation and advanced lung diseases. He currently directs the pulmonary research program at the Duke Clinical Research Institute (DCRI) and serves as Vice Chair for Research in the Department of Medicine.

Dr. Palmer has over 150 peer reviewed publications, received numerous awards, including election into the American Society for Clinical Investigation (ASCI) in 2012, chaired many sessions at national and international meetings, serves regularly on NIH study sections, and is on the editorial board of many prominent journals. He is also Associate Director of the Clinical Research Training Program at Duke and has personally mentored over 40 pre-and post-doctoral trainees, many of whom are now engaged in their own successful research careers.

His scientific accomplishments include the first human studies to demonstrate the importance of innate immunity in transplant rejection and completion of a prospective multicenter study that improved CMV prevention after lung transplantation.

Current basic projects in the lab are studying the role of the matrix in the activation of innate immunity in pulmonary transplant rejection, and epithelial injury and repair in the development of toxin induced bronchiolitis obliterans. Translational and human projects are studying predictors of lung transplant survival in the UNOS database, immune monitoring to predict CMV infection and acute rejection after lung transplantation, and the use of novel inhaled antibiotics in lung transplantation. The lab is also using cutting edge whole exome genetic sequencing to identify genetic predictors of transplant rejection.

Dr. Palmer also leads trials coordinated through the DCRI that study the natural history and investigate new treatments for idiopathic pulmonary fibrosis (IPF), chronic lung transplant rejection, and posttransplant cytomegalovirus infection.

Education and Training

  • Fellow, Pulmonary Medicine, Medicine, Duke University, 1996 - 1999
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.H.S., Duke University, 2000
  • M.D., Duke University, 1993

Publications

Cantu, E, Suzuki, Y, Diamond, JM, Ellis, J, Tiwari, J, Beduhn, B, Nellen, JR, Shah, R, Meyer, NJ, Lederer, DJ, Kawut, SM, Palmer, SM, Snyder, LD, Hartwig, MG, Lama, VN, Bhorade, S, Crespo, M, Demissie, E, Wille, K, Orens, J, Shah, PD, Weinacker, A, Weill, D, Wilkes, D, Roe, D, Ware, LB, Wang, F, Feng, R, Christie, JD, and Lung Transplant Outcomes Group, . "Protein Quantitative Trait Loci Analysis Identifies Genetic Variation in the Innate Immune Regulator TOLLIP in Post-Lung Transplant Primary Graft Dysfunction Risk." American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons 16, no. 3 (March 2016): 833-840.

PMID
26663441
Full Text

DerHovanessian, A, Weigt, SS, Palchevskiy, V, Shino, MY, Sayah, DM, Gregson, AL, Noble, PW, Palmer, SM, Fishbein, MC, Kubak, BM, Ardehali, A, Ross, DJ, Saggar, R, Lynch, JP, Elashoff, RM, and Belperio, JA. "The Role of TGF-β in the Association Between Primary Graft Dysfunction and Bronchiolitis Obliterans Syndrome." American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 16, no. 2 (February 2016): 640-649.

PMID
26461171
Full Text

Smith, PJ, Blumenthal, JA, Hoffman, BM, Rivelli, SK, Palmer, SM, Davis, RD, and Mathew, JP. "Reduced Cerebral Perfusion Pressure during Lung Transplant Surgery Is Associated with Risk, Duration, and Severity of Postoperative Delirium." Annals of the American Thoracic Society 13, no. 2 (February 2016): 180-187.

PMID
26731642
Full Text

Blumenthal, JA, Smith, PJ, Durheim, M, Mabe, S, Emery, CF, Martinu, T, Diaz, PT, Babyak, M, Welty-Wolf, K, and Palmer, S. "Biobehavioral Prognostic Factors in Chronic Obstructive Pulmonary Disease: Results From the INSPIRE-II Trial." Psychosomatic medicine 78, no. 2 (February 2016): 153-162.

PMID
26780299
Full Text

O'Brien, EC, Durheim, MT, Gamerman, V, Garfinkel, S, Anstrom, KJ, Palmer, SM, and Conoscenti, CS. "Rationale for and design of the Idiopathic Pulmonary Fibrosis-PRospective Outcomes (IPF-PRO) registry." Bmj Open Respiratory Research 3, no. 1 (January 11, 2016): e000108-null.

PMID
26835134
Full Text

Smith, PJ, Blumenthal, JA, Trulock, EP, Freedland, KE, Carney, RM, Davis, RD, Hoffman, BM, and Palmer, SM. "Psychosocial Predictors of Mortality Following Lung Transplantation." AMERICAN JOURNAL OF TRANSPLANTATION 16, no. 1 (January 2016): 271-277.

Full Text

Smith, PJ, Blumenthal, JA, Trulock, EP, Freedland, KE, Carney, RM, Davis, RD, Hoffman, BM, and Palmer, SM. "Psychosocial Predictors of Mortality Following Lung Transplantation." American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons 16, no. 1 (January 2016): 271-277.

PMID
26366639
Full Text

Brass, DM, Gwinn, WM, Valente, A, Kelly, FL, Brinkley, C, Nagler, A, Moseley, A, Morgan, DL, Palmer, SM, and Foster, MW. "Artificial Butter Flavoring Exposure Causes An Extracellular Matrix Reorganizing Proteomic Signature In Primary Human Airway Epithelial Cells." 2016.

Scholars@Duke

Brass, DM, Kelly, FL, Gwinn, WM, Brinkley, C, Nagler, A, Morgan, DL, Foster, MW, and Palmer, SM. "Synthesis Of A Cross-Linked Hyaluronan Matrix By The Airway Epithelium In Experimental Bronchiolitis Obliterans." 2016.

Scholars@Duke

Foster, MW, Gwinn, WM, Kelly, FL, Brass, DM, Thompson, JW, Moseley, MA, Morgan, DL, and Palmer, SM. "Proteomic Analysis Reveals Significant Epithelial Remodeling After In Vitro Exposure To Diacetyl Vapor." 2016.

Scholars@Duke

Pages