Seungkirl Ahn, PhD

Publications

Ren, X-R, Reiter, E, Ahn, S, Kim, J, Chen, W, and Lefkowitz, RJ. "Different G protein-coupled receptor kinases govern G protein and beta-arrestin-mediated signaling of V2 vasopressin receptor." Proc Natl Acad Sci U S A 102, no. 5 (February 1, 2005): 1448-1453.

PMID
15671180
Full Text

Kim, J, Ahn, S, Ren, X-R, Whalen, EJ, Reiter, E, Wei, H, and Lefkowitz, RJ. "Functional antagonism of different G protein-coupled receptor kinases for beta-arrestin-mediated angiotensin II receptor signaling." Proc Natl Acad Sci U S A 102, no. 5 (February 1, 2005): 1442-1447.

PMID
15671181
Full Text

Wei, H, Ahn, S, Barnes, WG, and Lefkowitz, RJ. "Stable interaction between beta-arrestin 2 and angiotensin type 1A receptor is required for beta-arrestin 2-mediated activation of extracellular signal-regulated kinases 1 and 2." J Biol Chem 279, no. 46 (November 12, 2004): 48255-48261.

PMID
15355986
Full Text

Ahn, S, Shenoy, SK, Wei, H, and Lefkowitz, RJ. "Differential kinetic and spatial patterns of beta-arrestin and G protein-mediated ERK activation by the angiotensin II receptor." J Biol Chem 279, no. 34 (August 20, 2004): 35518-35525.

PMID
15205453
Full Text

Ahn, S, Wei, H, Garrison, TR, and Lefkowitz, RJ. "Reciprocal regulation of angiotensin receptor-activated extracellular signal-regulated kinases by beta-arrestins 1 and 2." J Biol Chem 279, no. 9 (February 27, 2004): 7807-7811.

PMID
14711824
Full Text

Wei, H, Ahn, S, Shenoy, SK, Karnik, SS, Hunyady, L, Luttrell, LM, and Lefkowitz, RJ. "Independent beta-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2." Proceedings of the National Academy of Sciences of the United States of America 100, no. 19 (September 2003): 10782-10787.

PMID
12949261
Full Text

Chen, W, ten Berge, D, Brown, J, Ahn, S, Hu, LA, Miller, WE, Caron, MG, Barak, LS, Nusse, R, and Lefkowitz, RJ. "Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4." Science (New York, N.Y.) 301, no. 5638 (September 2003): 1391-1394.

PMID
12958364
Full Text

Kim, J, Ahn, S, Guo, R, and Daaka, Y. "Regulation of epidermal growth factor receptor internalization by G protein-coupled receptors." Biochemistry 42, no. 10 (March 18, 2003): 2887-2894.

PMID
12627954
Full Text

Ahn, S, Nelson, CD, Garrison, TR, Miller, WE, and Lefkowitz, RJ. "Desensitization, internalization, and signaling functions of beta-arrestins demonstrated by RNA interference." Proc Natl Acad Sci U S A 100, no. 4 (February 18, 2003): 1740-1744.

PMID
12582207
Full Text

Ahn, S, Kim, J, Lucaveche, CL, Reedy, MC, Luttrell, LM, Lefkowitz, RJ, and Daaka, Y. "Src-dependent tyrosine phosphorylation regulates dynamin self-assembly and ligand-induced endocytosis of the epidermal growth factor receptor." The Journal of Biological Chemistry 277, no. 29 (July 2002): 26642-26651.

PMID
12011079
Full Text

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