Education and Training
- Ph.D., Duke University, 2002
Wei, H, Ahn, S, Barnes, WG, and Lefkowitz, RJ. "Stable interaction between beta-arrestin 2 and angiotensin type 1A receptor is required for beta-arrestin 2-mediated activation of extracellular signal-regulated kinases 1 and 2." J Biol Chem 279, no. 46 (November 12, 2004): 48255-48261.
Ahn, S, Shenoy, SK, Wei, H, and Lefkowitz, RJ. "Differential kinetic and spatial patterns of beta-arrestin and G protein-mediated ERK activation by the angiotensin II receptor." J Biol Chem 279, no. 34 (August 20, 2004): 35518-35525.
Ahn, S, Wei, H, Garrison, TR, and Lefkowitz, RJ. "Reciprocal regulation of angiotensin receptor-activated extracellular signal-regulated kinases by beta-arrestins 1 and 2." J Biol Chem 279, no. 9 (February 27, 2004): 7807-7811.
Wei, H, Ahn, S, Shenoy, SK, Karnik, SS, Hunyady, L, Luttrell, LM, and Lefkowitz, RJ. "Independent beta-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2." Proc Natl Acad Sci U S A 100, no. 19 (September 16, 2003): 10782-10787.
Chen, W, ten Berge, D, Brown, J, Ahn, S, Hu, LA, Miller, WE, Caron, MG, Barak, LS, Nusse, R, and Lefkowitz, RJ. "Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4." Science 301, no. 5638 (September 5, 2003): 1391-1394.
Kim, J, Ahn, S, Guo, R, and Daaka, Y. "Regulation of epidermal growth factor receptor internalization by G protein-coupled receptors." Biochemistry 42, no. 10 (March 18, 2003): 2887-2894.
Ahn, S, Nelson, CD, Garrison, TR, Miller, WE, and Lefkowitz, RJ. "Desensitization, internalization, and signaling functions of beta-arrestins demonstrated by RNA interference." Proc Natl Acad Sci U S A 100, no. 4 (February 18, 2003): 1740-1744.
Ahn, S, Kim, J, Lucaveche, CL, Reedy, MC, Luttrell, LM, Lefkowitz, RJ, and Daaka, Y. "Src-dependent tyrosine phosphorylation regulates dynamin self-assembly and ligand-induced endocytosis of the epidermal growth factor receptor." J Biol Chem 277, no. 29 (July 19, 2002): 26642-26651.
Pierce, KL, Tohgo, A, Ahn, S, Field, ME, Luttrell, LM, and Lefkowitz, RJ. "Epidermal growth factor (EGF) receptor-dependent ERK activation by G protein-coupled receptors: a co-culture system for identifying intermediates upstream and downstream of heparin-binding EGF shedding." J Biol Chem 276, no. 25 (June 22, 2001): 23155-23160.
Miller, WE, Maudsley, S, Ahn, S, Khan, KD, Luttrell, LM, and Lefkowitz, RJ. "beta-arrestin1 interacts with the catalytic domain of the tyrosine kinase c-SRC. Role of beta-arrestin1-dependent targeting of c-SRC in receptor endocytosis." J Biol Chem 275, no. 15 (April 14, 2000): 11312-11319.