Sudarshan Rajagopal, MD, PhD

Associate Professor of Medicine
Assistant Professor in Biochemistry
Campus mail 102147, Durham, NC 27710
Phone (919) 684-6237
Email address sudarshan.rajagopal@duke.edu

I am a physician-scientist with a research focus on G protein-coupled receptor signaling in inflammation and vascular disease and a clinical focus on pulmonary vascular disease. I serve as Co-Director of the Duke Pulmonary Vascular Disease Center.

In Their Words

Education and Training

  • Clinical Fellowship, Cardiovascular Disease, Duke University School of Medicine, 2011 - 2013
  • Research Fellowship, Duke University School of Medicine, 2008 - 2011
  • Resident, Internal Medicine, Duke University School of Medicine, 2006 - 2008
  • M.D., The University of Chicago, 2006
  • Ph.D., The University of Chicago, 2004

Publications

Alenezi, Fawaz, Taylor A. Covington, Monica Mukherjee, Stephen C. Mathai, Paul B. Yu, and Sudarshan Rajagopal. “Novel Approaches to Imaging the Pulmonary Vasculature and Right Heart.” Circ Res 130, no. 9 (April 29, 2022): 1445–65. https://doi.org/10.1161/CIRCRESAHA.121.319990.

PMID
35482838
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Zheng, Kevin, Jeffrey S. Smith, Dylan S. Eiger, Anmol Warman, Issac Choi, Christopher C. Honeycutt, Noelia Boldizsar, et al. “Biased agonists of the chemokine receptor CXCR3 differentially signal through Gαi:β-arrestin complexes.” Sci Signal 15, no. 726 (March 22, 2022): eabg5203. https://doi.org/10.1126/scisignal.abg5203.

PMID
35316095
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Park, Saejeong, Zhiyuan Ma, Georgia Zarkada, Irinna Papangeli, Sarin Paluri, Nour Nazo, Xinyu Xiong, et al. “Endothelial β-arrestins Regulate Mechanotransduction by the Type II Bone Morphogenetic Protein Receptor in Primary Cilia.” BioRxiv, February 5, 2022. https://doi.org/10.1101/2022.02.04.479175.

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Edmonston, Daniel L., Roland Matsouaka, Svati H. Shah, Sudarshan Rajagopal, and Myles Wolf. “Noninvasive Risk Score to Screen for Pulmonary Hypertension With Elevated Pulmonary Vascular Resistance in Diseases of Chronic Volume Overload.” Am J Cardiol 159 (November 15, 2021): 113–20. https://doi.org/10.1016/j.amjcard.2021.08.016.

PMID
34497006
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Nathan, Steven D., Aaron Waxman, Sudarshan Rajagopal, Amy Case, Shilpa Johri, Hilary DuBrock, David J. De La Zerda, et al. “Inhaled treprostinil and forced vital capacity in patients with interstitial lung disease and associated pulmonary hypertension: a post-hoc analysis of the INCREASE study.” Lancet Respir Med 9, no. 11 (November 2021): 1266–74. https://doi.org/10.1016/S2213-2600(21)00165-X.

PMID
34214475
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Ma, Zhiyuan, Gayathri Viswanathan, Mason Sellig, Chanpreet Jassal, Issac Choi, Aditi Garikipati, Xinyu Xiong, Nour Nazo, and Sudarshan Rajagopal. “β-Arrestin-Mediated Angiotensin II Type 1 Receptor Activation Promotes Pulmonary Vascular Remodeling in Pulmonary Hypertension.” Jacc Basic Transl Sci 6, no. 11 (November 2021): 854–69. https://doi.org/10.1016/j.jacbts.2021.09.006.

PMID
34869949
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Alba, George A., Deepak Atri, Sriranjani Darbha, Inderjit Singh, Victor F. Tapson, Michael I. Lewis, Hyung J. Chun, Yen-Rei Yu, Bradley A. Maron, and Sudarshan Rajagopal. “Chronic Thromboembolic Pulmonary Hypertension: the Bench.” Curr Cardiol Rep 23, no. 10 (August 19, 2021): 141. https://doi.org/10.1007/s11886-021-01572-6.

PMID
34410515
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Matusov, Yuri, Inderjit Singh, Yen-Rei Yu, Hyung J. Chun, Bradley A. Maron, Victor F. Tapson, Michael I. Lewis, and Sudarshan Rajagopal. “Chronic Thromboembolic Pulmonary Hypertension: the Bedside.” Curr Cardiol Rep 23, no. 10 (August 19, 2021): 147. https://doi.org/10.1007/s11886-021-01573-5.

PMID
34410530
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