Teresa Kathleen Tarrant, MD

Associate Professor of Medicine
Campus mail 200 Trent Dr., DUMC 3874, Durham, NC 27710
Phone (919) 684-4499
Email address teresa.tarrant@duke.edu

I first became interested in clinical immunology as a medical student studying autoimmune inflammatory eye disease at the National Institutes of Health.  Since then, I have been inspired to understand what causes autoimmunity and immune deficiency disorders in order to improve the quality of life for my patients.  I see patients with multiple complex immune disorders with particular expertise in autoimmune and Rheumatoid arthritis, primary Sjogren's syndrome, and the immunodeficiency disoders Common Variable Immunodeficiency (CVID), Adenosine Deaminase Deficiency (ADA) disorders, and WHIM (Warts, Hypogammaglobulinemia, Infections, and Myelokathexis). My research investigates immune targets that may impact either the development of immune disease or identify new therapies for patients.  The goal is to help us understand why and how immunologic diseases develop so that we may better treat them.

Education and Training

  • Immunology Postdoctoral Fellowship, Thurston Arthritis Research Center, University of North Carolina - Chapel Hill, 2004 - 2005
  • Allergy and Immunology Fellowship, Medicine, Duke University School of Medicine, 2002 - 2005
  • Rheumatology Fellowship, Medicine, Duke University School of Medicine, 2001 - 2005
  • Internal Medicine Residency, Clinical Investigator Pathway, Duke University School of Medicine, 1999 - 2001
  • M.D., University of Florida, College of Medicine, 1999

Publications

Otani, Iris M., Heather K. Lehman, Artemio M. Jongco, Lulu R. Tsao, Antoine E. Azar, Teresa K. Tarrant, Elissa Engel, et al. “Practical guidance for the diagnosis and management of secondary hypogammaglobulinemia: A Work Group Report of the AAAAI Primary Immunodeficiency and Altered Immune Response Committees.” J Allergy Clin Immunol 149, no. 5 (May 2022): 1525–60. https://doi.org/10.1016/j.jaci.2022.01.025.

PMID
35176351
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Malcolm, Elizabeth J., Zachary Brandon, Lauren E. Wilson, John Paul Shoup, Heather A. King, Allison Lewinski, Melissa A. Greiner, et al. “eConsults' Impact on Care Access and Wait Times in Rheumatology.” J Clin Rheumatol 28, no. 3 (April 1, 2022): 147–54. https://doi.org/10.1097/RHU.0000000000001825.

PMID
35067514
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Brozowski, Jaime M., Roman G. Timoshchenko, D Stephen Serafin, Brittney Allyn, Jessica Koontz, Emily M. Rabjohns, Rishi R. Rampersad, et al. “G protein-coupled receptor kinase 3 modulates mesenchymal stem cell proliferation and differentiation through sphingosine-1-phosphate receptor regulation.” In Stem Cell Res Ther, 13:37, 2022. https://doi.org/10.1186/s13287-022-02715-4.

PMID
35093170
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Kienle, Korbinian, Katharina M. Glaser, Sarah Eickhoff, Michael Mihlan, Konrad Knöpper, Eduardo Reátegui, Maximilian W. Epple, et al. “Neutrophils self-limit swarming to contain bacterial growth in vivo.” Science 372, no. 6548 (June 18, 2021). https://doi.org/10.1126/science.abe7729.

PMID
34140358
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Rabjohns, Emily M., Katlyn Hurst, Arin Ghosh, Maria C. Cuellar, Rishi R. Rampersad, and Teresa K. Tarrant. “Paget's Disease of Bone: Osteoimmunology and Osteoclast Pathology.” Curr Allergy Asthma Rep 21, no. 4 (March 25, 2021): 23. https://doi.org/10.1007/s11882-021-01001-2.

PMID
33768371
Full Text

Chu, Philip, Maria C. Cuellar, Sonali J. Bracken, and Teresa K. Tarrant. “A Mimic of Ankylosing Spondylitis, Ochronosis: Case Report and Review of the Literature.” Curr Allergy Asthma Rep 21, no. 3 (March 5, 2021): 19. https://doi.org/10.1007/s11882-021-01002-1.

PMID
33666743
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Udupa, Akrithi, David Leverenz, Stephen J. Balevic, Rebecca E. Sadun, Teresa K. Tarrant, and Jennifer L. Rogers. “Hydroxychloroquine and COVID-19: a Rheumatologist's Take on the Lessons Learned.” Curr Allergy Asthma Rep 21, no. 1 (January 21, 2021): 5. https://doi.org/10.1007/s11882-020-00983-9.

PMID
33475900
Full Text

Vickerman, Brianna M., Emilia M. Zywot, Teresa K. Tarrant, and David S. Lawrence. “Taking phototherapeutics from concept to clinical launch.” Nat Rev Chem 5, no. 11 (2021): 816–34. https://doi.org/10.1038/s41570-021-00326-w.

PMID
34632078
Full Text

Tarrant, T. K., S. J. Kelly, and M. S. Hershfield. “Elucidating the pathogenesis of adenosine deaminase 2 deficiency: current status and unmet needs.” Expert Opinion on Orphan Drugs 9, no. 11–12 (January 1, 2021): 257–64. https://doi.org/10.1080/21678707.2021.2050367.

Full Text

Min, Hyunjung, Li Xu, Roberta Parrott, Christopher C. Overall, Melina Lillich, Emily M. Rabjohns, Rishi R. Rampersad, et al. “Mesenchymal stromal cells reprogram monocytes and macrophages with processing bodies.” Stem Cells 39, no. 1 (January 2021): 115–28. https://doi.org/10.1002/stem.3292.

PMID
33166420
Full Text

Pages