Rheumatology and Immunology

Teresa Kathleen Tarrant, MD

Associate Professor of Medicine
Campus mail 200 Trent Dr., DUMC 3874, Durham, NC 27710
Phone (919) 684-6797
Email address teresa.tarrant@duke.edu

I first became interested in clinical immunology as a medical student studying autoimmune inflammatory eye disease at the National Institutes of Health.  Since then, I have been inspired to understand what causes autoimmunity and immune deficiency disorders in order to improve the quality of life for my patients.  I see patients with multiple complex immune disorders with particular expertise in autoimmune and Rheumatoid arthritis, primary Sjogren's syndrome, and Common Variable Immunodeficiency (CVID). My research investigates immune targets that may impact either the development of immune disease or identify new therapies for patients.  The goal is to help us understand why and how immunologic diseases develop so that we may better treat them.

Education and Training

  • Immunology Postdoctoral Fellowship, Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, 2004 - 2005
  • Allergy and Immunology Fellowship, Medicine, Duke University School of Medicine, 2002 - 2005
  • Rheumatology Fellowship, Medicine, Duke University School of Medicine, 2001 - 2005
  • Internal Medicine Residency, Clinical Investigator Pathway, Duke University School of Medicine, 1999 - 2001
  • M.D., University of Florida College of Medicine, 1999

Grants

Publications

Rolfes, MC, Sriaroon, P, Dávila Saldaña, BJ, Dvorak, CC, Chapdelaine, H, Ferdman, RM, Chen, K, Jolles, S, Patel, NC, Kim, YJ, Tarrant, TK, Martelius, T, Seppanen, M, and Joshi, AY. "Chronic norovirus infection in primary immune deficiency disorders: an international case series." Diagnostic Microbiology and Infectious Disease (August 12, 2018).

PMID
30174143
Full Text

Tarrant, TK, Marvin, C, Wang, Q, Serafin, S, and Lawrence, D. "Light-Mediated Delivery of Therapeutics." American-Academy-of-Allergy-Asthma-and-Immunology / World-Allergy-Organization Joint Congress. Orlando, FL. March 2, 2018 - March 8, 2018.: MOSBY-ELSEVIER, February 1, 2018.

Scholars@Duke

Tarrant, TK, Marvin, C, Wang, Q, Serafin, S, and Lawrence, D. "Light-Mediated Delivery of Therapeutics." American-Academy-of-Allergy-Asthma-and-Immunology / World-Allergy-Organization Joint Congress. Orlando, FL. March 2, 2018 - March 8, 2018.: MOSBY-ELSEVIER, February 1, 2018.

Scholars@Duke

Brozowski, JM, Timoshchenko, RG, Serafin, DS, Koontz, J, Allyn, B, Eudy, AM, Harris, T, Abraham, D, Rubin, CT, Rubin, J, Allbritton, N, Billard, MJ, and Tarrant, TK. "G Protein-Coupled Receptor Kinase 3 Modulates Mesenchymal Stem Cell Proliferation and Differentiation through Sphingosine-1-Phosphate Receptor Regulation.": WILEY, October 1, 2017.

Scholars@Duke

Brozowski, JM, Timoshchenko, RG, Serafin, DS, Koontz, J, Allyn, B, Eudy, AM, Harris, T, Abraham, D, Rubin, CT, Rubin, J, Allbritton, N, Billard, MJ, and Tarrant, TK. "G Protein-Coupled Receptor Kinase 3 Modulates Mesenchymal Stem Cell Proliferation and Differentiation through Sphingosine-1-Phosphate Receptor Regulation.": WILEY, October 1, 2017.

Scholars@Duke

Mainz, ER, Serafin, DS, Nguyen, TT, Tarrant, TK, Sims, CE, and Allbritton, NL. "Single Cell Chemical Cytometry of Akt Activity in Rheumatoid Arthritis and Normal Fibroblast-like Synoviocytes in Response to Tumor Necrosis Factor α." Analytical Chemistry 88, no. 15 (August 2016): 7786-7792.

PMID
27391352
Full Text

Kang, S, Rogers, JL, Monteith, AJ, Jiang, C, Schmitz, J, Clarke, SH, Tarrant, TK, Truong, YK, Diaz, M, Fedoriw, Y, and Vilen, BJ. "Apoptotic Debris Accumulates on Hematopoietic Cells and Promotes Disease in Murine and Human Systemic Lupus Erythematosus." Journal of Immunology (Baltimore, Md. : 1950) 196, no. 10 (May 2016): 4030-4039.

PMID
27059595
Full Text

Yang, L, Shah, SN, Serafin, DS, Timoshchenko, RG, Scotland, P, Richards, K, Billard, MJ, Lugar, PL, and Tarrant, TK. "Interrogating Genetic Susceptibility Loci in CVID and Autoimmunity." February 2016.

Full Text

Billard, MJ, Fitzhugh, DJ, Parker, JS, Brozowski, JM, McGinnis, MW, Timoshchenko, RG, Serafin, DS, Lininger, R, Klauber-Demore, N, Sahagian, G, Truong, YK, Sassano, MF, Serody, JS, and Tarrant, TK. "G Protein Coupled Receptor Kinase 3 Regulates Breast Cancer Migration, Invasion, and Metastasis." Plos One 11, no. 4 (January 2016): e0152856-null.

PMID
27049755
Full Text

Tarrant, TK, Billard, MJ, Timoshchenko, RG, McGinnis, MW, Stephen Serafin, D, Foreman, O, Esserman, DA, Chao, NJ, Lento, WE, Lee, DM, Patel, D, and Siderovski, DP. "G protein-coupled receptor kinase-3-deficient mice exhibit WHIM syndrome features and attenuated inflammatory responses." Journal of Leukocyte Biology 94, no. 6 (December 1, 2013): 1243-1251.

PMID
23935208
Full Text

Pages