Rheumatology and Immunology

Teresa Kathleen Tarrant, MD

Associate Professor of Medicine
Campus mail 200 Trent Dr., DUMC 3874, Durham, NC 27710
Phone (919) 684-6797
Email address teresa.tarrant@duke.edu

I first became interested in clinical immunology as a medical student studying autoimmune inflammatory eye disease at the National Institutes of Health.  Since then, I have been inspired to understand what causes autoimmunity and immune deficiency disorders in order to improve the quality of life for my patients.  I see patients with multiple complex immune disorders with particular expertise in autoimmune and Rheumatoid arthritis, primary Sjogren's syndrome, and Common Variable Immunodeficiency (CVID). My research investigates immune targets that may impact either the development of immune disease or identify new therapies for patients.  The goal is to help us understand why and how immunologic diseases develop so that we may better treat them.

Education and Training

  • Immunology Postdoctoral Fellowship, Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, 2004 - 2005
  • Allergy and Immunology Fellowship, Medicine, Duke University School of Medicine, 2002 - 2005
  • Rheumatology Fellowship, Medicine, Duke University School of Medicine, 2001 - 2005
  • Internal Medicine Residency, Clinical Investigator Pathway, Duke University School of Medicine, 1999 - 2001
  • M.D., University of Florida College of Medicine, 1999

Grants

Publications

Chinn, Ivan K., Alice Y. Chan, Karin Chen, Janet Chou, Morna J. Dorsey, Joud Hajjar, Artemio M. Jongco, et al. “Diagnostic interpretation of genetic studies in patients with primary immunodeficiency diseases: A working group report of the Primary Immunodeficiency Diseases Committee of the American Academy of Allergy, Asthma & Immunology.” J Allergy Clin Immunol 145, no. 1 (January 2020): 46–69. https://doi.org/10.1016/j.jaci.2019.09.009.

PMID
31568798
Full Text

Marvin, Christina M., Song Ding, Rachel E. White, Natalia Orlova, Qunzhao Wang, Emilia M. Zywot, Brianna M. Vickerman, et al. “On Command Drug Delivery via Cell-Conveyed Phototherapeutics.” Small 15, no. 37 (September 2019): e1901442. https://doi.org/10.1002/smll.201901442.

PMID
31353802
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Wickenheisser, Victoria A., Emilia Marta Zywot, Emily Mary Rabjohns, Hyun Ho Lee, David S. Lawrence, and Teresa Kathleen Tarrant. “Laser Light Therapy in Inflammatory, Musculoskeletal, and Autoimmune Disease.” Curr Allergy Asthma Rep 19, no. 8 (July 2, 2019): 37. https://doi.org/10.1007/s11882-019-0869-z.

PMID
31267251
Full Text

Serafin, D Stephen, Brittney Allyn, Maria F. Sassano, Roman G. Timoshchenko, Daniel Mattox, Jaime M. Brozowski, David P. Siderovski, et al. “Chemerin-activated functions of CMKLR1 are regulated by G protein-coupled receptor kinase 6 (GRK6) and β-arrestin 2 in inflammatory macrophages.” Mol Immunol 106 (February 2019): 12–21. https://doi.org/10.1016/j.molimm.2018.12.016.

PMID
30576947
Full Text

Rolfes, M. C., P. Sriaroon, B. J. Dávila Saldaña, C. C. Dvorak, H. Chapdelaine, R. M. Ferdman, K. Chen, et al. “Chronic norovirus infection in primary immune deficiency disorders: an international case series.” Diagn Microbiol Infect Dis 93, no. 1 (January 2019): 69–73. https://doi.org/10.1016/j.diagmicrobio.2018.08.002.

PMID
30174143
Full Text

Tarrant, Teresa K., Christina Marvin, Qunzhao Wang, Stephen Serafin, and David Lawrence. “Light-Mediated Delivery of Therapeutics.” In Journal of Allergy and Clinical Immunology, 141:AB197–AB197. MOSBY-ELSEVIER, 2018.

Scholars@Duke

Brozowski, Jaime M., Roman G. Timoshchenko, D Stephen Serafin, Jessica Koontz, Brittney Allyn, Amanda M. Eudy, Taylor Harris, et al. “G Protein-Coupled Receptor Kinase 3 Modulates Mesenchymal Stem Cell Proliferation and Differentiation through Sphingosine-1-Phosphate Receptor Regulation.” In Arthritis & Rheumatology, Vol. 69. WILEY, 2017.

Scholars@Duke

Mainz, Emilie R., D Stephen Serafin, Tuong T. Nguyen, Teresa K. Tarrant, Christopher E. Sims, and Nancy L. Allbritton. “Single Cell Chemical Cytometry of Akt Activity in Rheumatoid Arthritis and Normal Fibroblast-like Synoviocytes in Response to Tumor Necrosis Factor α.” Anal Chem 88, no. 15 (August 2, 2016): 7786–92. https://doi.org/10.1021/acs.analchem.6b01801.

PMID
27391352
Full Text

Kang, SunAh, Jennifer L. Rogers, Andrew J. Monteith, Chuancang Jiang, John Schmitz, Stephen H. Clarke, Teresa K. Tarrant, et al. “Apoptotic Debris Accumulates on Hematopoietic Cells and Promotes Disease in Murine and Human Systemic Lupus Erythematosus.” J Immunol 196, no. 10 (May 15, 2016): 4030–39. https://doi.org/10.4049/jimmunol.1500418.

PMID
27059595
Full Text

Yang, Luanna, Shaili N. Shah, D Stephen Serafin, Roman G. Timoshchenko, Paula Scotland, Kristy Richards, Matthew J. Billard, Patricia L. Lugar, and Teresa K. Tarrant. “Interrogating Genetic Susceptibility Loci in CVID and Autoimmunity.” In Journal of Allergy and Clinical Immunology, 137:AB179–AB179. Elsevier BV, 2016. https://doi.org/10.1016/j.jaci.2015.12.720.

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