Education and Training
- Ph.D., University of Texas at Dallas, 1997
Zhang, Guo-Fang, Mette V. Jensen, Sarah M. Gray, Kimberley El, You Wang, Danhong Lu, Thomas C. Becker, Jonathan E. Campbell, and Christopher B. Newgard. “Reductive TCA cycle metabolism fuels glutamine- and glucose-stimulated insulin secretion.” Cell Metab 33, no. 4 (April 6, 2021): 804-817.e5. https://doi.org/10.1016/j.cmet.2020.11.020.
Khan, Md Wasim, Medha Priyadarshini, Jose Cordoba-Chacon, Thomas C. Becker, and Brian T. Layden. “Hepatic hexokinase domain containing 1 (HKDC1) improves whole body glucose tolerance and insulin sensitivity in pregnant mice.” Biochim Biophys Acta Mol Basis Dis 1865, no. 3 (March 1, 2019): 678–87. https://doi.org/10.1016/j.bbadis.2018.11.022.
Haldeman, Jonathan M., Amanda E. Conway, Michelle E. Arlotto, Dorothy H. Slentz, Deborah M. Muoio, Thomas C. Becker, and Christopher B. Newgard. “Creation of versatile cloning platforms for transgene expression and dCas9-based epigenome editing.” Nucleic Acids Res 47, no. 4 (February 28, 2019): e23. https://doi.org/10.1093/nar/gky1286.
Oh, Eunjin, Miwon Ahn, Solomon Afelik, Thomas C. Becker, Bart O. Roep, and Debbie C. Thurmond. “Syntaxin 4 Expression in Pancreatic β-Cells Promotes Islet Function and Protects Functional β-Cell Mass.” Diabetes 67, no. 12 (December 2018): 2626–39. https://doi.org/10.2337/db18-0259.
Wang, Huan, Aaron Bender, Peng Wang, Esra Karakose, William B. Inabnet, Steven K. Libutti, Andrew Arnold, et al. “Insights into beta cell regeneration for diabetes via integration of molecular landscapes in human insulinomas.” Nat Commun 8, no. 1 (October 3, 2017): 767. https://doi.org/10.1038/s41467-017-00992-9.
Hayes, Heather L., Lu Zhang, Thomas C. Becker, Jonathan M. Haldeman, Samuel B. Stephens, Michelle Arlotto, Larry G. Moss, Christopher B. Newgard, and Hans E. Hohmeier. “A Pdx-1-Regulated Soluble Factor Activates Rat and Human Islet Cell Proliferation.” Mol Cell Biol 36, no. 23 (December 1, 2016): 2918–30. https://doi.org/10.1128/MCB.00103-16.
Rosario, Wilfredo, Inderroop Singh, Arnaud Wautlet, Christa Patterson, Jonathan Flak, Thomas C. Becker, Almas Ali, et al. “The Brain-to-Pancreatic Islet Neuronal Map Reveals Differential Glucose Regulation From Distinct Hypothalamic Regions.” Diabetes 65, no. 9 (September 2016): 2711–23. https://doi.org/10.2337/db15-0629.
Marzban, L., A. Tomas, T. C. Becker, L. Rosenberg, J. Oberholzer, P. E. Fraser, P. A. Halban, and C. B. Verchere. “Erratum: Small interfering RNA-mediated suppression of proislet amyloid polypeptide expression inhibits islet amyloid formation and enhances survival of human islets in culture (Diabetes (2008) 57 (3045-3055)).” Diabetes 65, no. 3 (March 1, 2016): 818. https://doi.org/10.2337/db16-er03.
Guo, Cong, Anton E. Ludvik, Michelle E. Arlotto, M Geoffrey Hayes, Loren L. Armstrong, Denise M. Scholtens, Christopher D. Brown, et al. “Coordinated regulatory variation associated with gestational hyperglycaemia regulates expression of the novel hexokinase HKDC1.” Nat Commun 6 (February 4, 2015): 6069. https://doi.org/10.1038/ncomms7069.