Thomas Charles Becker, PhD

Publications

Wang, H, Bender, A, Wang, P, Karakose, E, Inabnet, WB, Libutti, SK, Arnold, A, Lambertini, L, Stang, M, Chen, H, Kasai, Y, Mahajan, M, Kinoshita, Y, Fernandez-Ranvier, G, Becker, TC, Takane, KK, Walker, LA, Saul, S, Chen, R, Scott, DK, Ferrer, J, Antipin, Y, Donovan, M, Uzilov, AV, Reva, B, Schadt, EE, Losic, B, Argmann, C, and Stewart, AF. "Insights into beta cell regeneration for diabetes via integration of molecular landscapes in human insulinomas." Nature Communications 8, no. 1 (October 3, 2017): 767-null.

PMID
28974674
Full Text

Hayes, HL, Zhang, L, Becker, TC, Haldeman, JM, Stephens, SB, Arlotto, M, Moss, LG, Newgard, CB, and Hohmeier, HE. "A Pdx-1-Regulated Soluble Factor Activates Rat and Human Islet Cell Proliferation." Molecular and Cellular Biology 36, no. 23 (December 2016): 2918-2930.

PMID
27620967
Full Text

Rosario, W, Singh, I, Wautlet, A, Patterson, C, Flak, J, Becker, TC, Ali, A, Tamarina, N, Philipson, LH, Enquist, LW, Myers, MG, and Rhodes, CJ. "The Brain-to-Pancreatic Islet Neuronal Map Reveals Differential Glucose Regulation From Distinct Hypothalamic Regions." Diabetes 65, no. 9 (September 2016): 2711-2723.

PMID
27207534
Full Text

Marzban, L, Tomas, A, Becker, TC, Rosenberg, L, Oberholzer, J, Fraser, PE, Halban, PA, and Verchere, CB. "Erratum. Small Interfering RNA—Mediated Suppression of Proislet Amyloid Polypeptide Expression Inhibits Islet Amyloid Formation and Enhances Survival of Human Islets in Culture. Diabetes 2008;57:3045—3055." Diabetes 65, no. 3 (March 2016): 818-818.

Full Text

Guo, C, Ludvik, AE, Arlotto, ME, Hayes, MG, Armstrong, LL, Scholtens, DM, Brown, CD, Newgard, CB, Becker, TC, Layden, BT, Lowe, WL, and Reddy, TE. "Coordinated regulatory variation associated with gestational hyperglycaemia regulates expression of the novel hexokinase HKDC1." Nature communications 6 (February 4, 2015): 6069-.

PMID
25648650
Full Text

Hobson, A, Draney, C, Stratford, A, Becker, TC, Lu, D, Arlotto, M, and Tessem, JS. "Aurora Kinase A is critical for the Nkx6.1 mediated β-cell proliferation pathway." Islets 7, no. 1 (January 2015): e1027854-null.

PMID
26030060
Full Text

Civitarese, AE, MacLean, PS, Carling, S, Kerr-Bayles, L, McMillan, RP, Pierce, A, Becker, TC, Moro, C, Finlayson, J, Lefort, N, Newgard, CB, Mandarino, L, Cefalu, W, Walder, K, Collier, GR, Hulver, MW, Smith, SR, and Ravussin, E. "Regulation of skeletal muscle oxidative capacity and insulin signaling by the mitochondrial rhomboid protease PARL." Cell Metab 11, no. 5 (May 5, 2010): 412-426.

PMID
20444421
Full Text

Odegaard, ML, Joseph, JW, Jensen, MV, Lu, D, Ilkayeva, O, Ronnebaum, SM, Becker, TC, and Newgard, CB. "The mitochondrial 2-oxoglutarate carrier is part of a metabolic pathway that mediates glucose- and glutamine-stimulated insulin secretion." The Journal of Biological Chemistry 285, no. 22 (May 2010): 16530-16537.

PMID
20356834
Full Text

Anderson, KR, Torres, CA, Solomon, K, Becker, TC, Newgard, CB, Wright, CV, Hagman, J, and Sussel, L. "Cooperative transcriptional regulation of the essential pancreatic islet gene NeuroD1 (beta2) by Nkx2.2 and neurogenin 3." The Journal of Biological Chemistry 284, no. 45 (November 2009): 31236-31248.

PMID
19759004
Full Text

Dunn-Meynell, AA, Sanders, NM, Compton, D, Becker, TC, Eiki, J-I, Zhang, BB, and Levin, BE. "Relationship among brain and blood glucose levels and spontaneous and glucoprivic feeding." The Journal of Neuroscience : the Official Journal of the Society for Neuroscience 29, no. 21 (May 2009): 7015-7022.

PMID
19474328
Full Text

Pages