Thomas Charles Becker, PhD

Publications

Khan, MW, Priyadarshini, M, Cordoba-Chacon, J, Becker, TC, and Layden, BT. "Hepatic hexokinase domain containing 1 (HKDC1) improves whole body glucose tolerance and insulin sensitivity in pregnant mice." Biochimica Et Biophysica Acta. Molecular Basis of Disease 1865, no. 3 (March 2019): 678-687.

PMID
30543855
Full Text

Pusec, CM, De Jesus, A, Khan, MW, Terry, AR, Ludvik, AE, Xu, K, Giancola, N, Pervaiz, H, Daviau Smith, E, Ding, X, Harrison, S, Chandel, NS, Becker, TC, Hay, N, Ardehali, H, Cordoba-Chacon, J, and Layden, BT. "Hepatic HKDC1 Expression Contributes to Liver Metabolism." Endocrinology 160, no. 2 (February 2019): 313-330.

PMID
30517626
Full Text

Haldeman, JM, Conway, AE, Arlotto, ME, Slentz, DH, Muoio, DM, Becker, TC, and Newgard, CB. "Creation of versatile cloning platforms for transgene expression and dCas9-based epigenome editing." Nucleic Acids Research 47, no. 4 (February 2019): e23-null.

PMID
30590691
Full Text

Oh, E, Ahn, M, Afelik, S, Becker, TC, Roep, BO, and Thurmond, DC. "Syntaxin 4 Expression in Pancreatic β-Cells Promotes Islet Function and Protects Functional β-Cell Mass." Diabetes 67, no. 12 (December 2018): 2626-2639.

PMID
30305365
Full Text

Wang, H, Bender, A, Wang, P, Karakose, E, Inabnet, WB, Libutti, SK, Arnold, A, Lambertini, L, Stang, M, Chen, H, Kasai, Y, Mahajan, M, Kinoshita, Y, Fernandez-Ranvier, G, Becker, TC, Takane, KK, Walker, LA, Saul, S, Chen, R, Scott, DK, Ferrer, J, Antipin, Y, Donovan, M, Uzilov, AV, Reva, B, Schadt, EE, Losic, B, Argmann, C, and Stewart, AF. "Insights into beta cell regeneration for diabetes via integration of molecular landscapes in human insulinomas." Nature Communications 8, no. 1 (October 3, 2017): 767-null.

PMID
28974674
Full Text

Hayes, HL, Zhang, L, Becker, TC, Haldeman, JM, Stephens, SB, Arlotto, M, Moss, LG, Newgard, CB, and Hohmeier, HE. "A Pdx-1-Regulated Soluble Factor Activates Rat and Human Islet Cell Proliferation." Molecular and Cellular Biology 36, no. 23 (December 2016): 2918-2930.

PMID
27620967
Full Text

Rosario, W, Singh, I, Wautlet, A, Patterson, C, Flak, J, Becker, TC, Ali, A, Tamarina, N, Philipson, LH, Enquist, LW, Myers, MG, and Rhodes, CJ. "The Brain-to-Pancreatic Islet Neuronal Map Reveals Differential Glucose Regulation From Distinct Hypothalamic Regions." Diabetes 65, no. 9 (September 2016): 2711-2723.

PMID
27207534
Full Text

Marzban, L, Tomas, A, Becker, TC, Rosenberg, L, Oberholzer, J, Fraser, PE, Halban, PA, and Verchere, CB. "Erratum. Small Interfering RNA—Mediated Suppression of Proislet Amyloid Polypeptide Expression Inhibits Islet Amyloid Formation and Enhances Survival of Human Islets in Culture. Diabetes 2008;57:3045—3055." Diabetes 65, no. 3 (March 2016): 818-818.

Full Text

Guo, C, Ludvik, AE, Arlotto, ME, Hayes, MG, Armstrong, LL, Scholtens, DM, Brown, CD, Newgard, CB, Becker, TC, Layden, BT, Lowe, WL, and Reddy, TE. "Coordinated regulatory variation associated with gestational hyperglycaemia regulates expression of the novel hexokinase HKDC1." Nature communications 6 (February 4, 2015): 6069-.

PMID
25648650
Full Text

Hobson, A, Draney, C, Stratford, A, Becker, TC, Lu, D, Arlotto, M, and Tessem, JS. "Aurora Kinase A is critical for the Nkx6.1 mediated β-cell proliferation pathway." Islets 7, no. 1 (January 2015): e1027854-null.

PMID
26030060
Full Text

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