Thomas Charles Becker, PhD

Publications

Odegaard, Matthew L., Jamie W. Joseph, Mette V. Jensen, Danhong Lu, Olga Ilkayeva, Sarah M. Ronnebaum, Thomas C. Becker, and Christopher B. Newgard. “The mitochondrial 2-oxoglutarate carrier is part of a metabolic pathway that mediates glucose- and glutamine-stimulated insulin secretion..” J Biol Chem 285, no. 22 (May 28, 2010): 16530–37. https://doi.org/10.1074/jbc.M109.092593.

PMID
20356834
Full Text

Civitarese, Anthony E., Paul S. MacLean, Stacy Carling, Lyndal Kerr-Bayles, Ryan P. McMillan, Anson Pierce, Thomas C. Becker, et al. “Regulation of skeletal muscle oxidative capacity and insulin signaling by the mitochondrial rhomboid protease PARL..” Cell Metab 11, no. 5 (May 5, 2010): 412–26. https://doi.org/10.1016/j.cmet.2010.04.004.

PMID
20444421
Full Text

Anderson, Keith R., Ciara A. Torres, Keely Solomon, Thomas C. Becker, Christopher B. Newgard, Christopher V. Wright, James Hagman, and Lori Sussel. “Cooperative transcriptional regulation of the essential pancreatic islet gene NeuroD1 (beta2) by Nkx2.2 and neurogenin 3..” J Biol Chem 284, no. 45 (November 6, 2009): 31236–48. https://doi.org/10.1074/jbc.M109.048694.

PMID
19759004
Full Text

Dunn-Meynell, Ambrose A., Nicole M. Sanders, Douglas Compton, Thomas C. Becker, Jun-ichi Eiki, Bei B. Zhang, and Barry E. Levin. “Relationship among brain and blood glucose levels and spontaneous and glucoprivic feeding..” J Neurosci 29, no. 21 (May 27, 2009): 7015–22. https://doi.org/10.1523/JNEUROSCI.0334-09.2009.

PMID
19474328
Full Text

Marzban, Lucy, Alejandra Tomas, Thomas C. Becker, Lawrence Rosenberg, Jose Oberholzer, Paul E. Fraser, Philippe A. Halban, and C Bruce Verchere. “Small interfering RNA-mediated suppression of proislet amyloid polypeptide expression inhibits islet amyloid formation and enhances survival of human islets in culture..” Diabetes 57, no. 11 (November 2008): 3045–55. https://doi.org/10.2337/db08-0485.

PMID
18694973
Full Text

Ronnebaum, Sarah M., Jamie W. Joseph, Olga Ilkayeva, Shawn C. Burgess, Danhong Lu, Thomas C. Becker, A Dean Sherry, and Christopher B. Newgard. “Chronic suppression of acetyl-CoA carboxylase 1 in beta-cells impairs insulin secretion via inhibition of glucose rather than lipid metabolism..” J Biol Chem 283, no. 21 (May 23, 2008): 14248–56. https://doi.org/10.1074/jbc.M800119200.

PMID
18381287
Full Text

Schisler, Jonathan C., Patrick T. Fueger, Daniella A. Babu, Hans E. Hohmeier, Jeffery S. Tessem, Danhong Lu, Thomas C. Becker, et al. “Stimulation of human and rat islet beta-cell proliferation with retention of function by the homeodomain transcription factor Nkx6.1..” Mol Cell Biol 28, no. 10 (May 2008): 3465–76. https://doi.org/10.1128/MCB.01791-07.

PMID
18347054
Full Text

Levin, Barry E., Thomas C. Becker, Jun-ichi Eiki, Bei B. Zhang, and Ambrose A. Dunn-Meynell. “Ventromedial hypothalamic glucokinase is an important mediator of the counterregulatory response to insulin-induced hypoglycemia..” Diabetes 57, no. 5 (May 2008): 1371–79. https://doi.org/10.2337/db07-1755.

PMID
18292346
Full Text

Schroeder-Gloeckler, Jill M., Shaikh Mizanoor Rahman, Rachel C. Janssen, Liping Qiao, Jianhua Shao, Michael Roper, Stephanie J. Fischer, et al. “CCAAT/enhancer-binding protein beta deletion reduces adiposity, hepatic steatosis, and diabetes in Lepr(db/db) mice..” J Biol Chem 282, no. 21 (May 25, 2007): 15717–29. https://doi.org/10.1074/jbc.M701329200.

PMID
17387171
Full Text

Hardy, Olga T., Hans E. Hohmeier, Thomas C. Becker, Elisabetta Manduchi, Nicolai M. Doliba, Rana K. Gupta, Peter White, et al. “Functional genomics of the beta-cell: short-chain 3-hydroxyacyl-coenzyme A dehydrogenase regulates insulin secretion independent of K+ currents..” Mol Endocrinol 21, no. 3 (March 2007): 765–73. https://doi.org/10.1210/me.2006-0411.

PMID
17185391
Full Text

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