Tomokazu Souma, MD, PhD

Medical Instructor in the Department of Medicine
Affiliate of the Regeneration Next Initiative
Email address tomokazu.souma@duke.edu

Education and Training

  • Post-doctoral Fellowship, Feinberg Cardiovascular Research Institute, Northwestern University, 2013 - 2014
  • Post-doctoral Fellowship, Department Of Medical Biochemistry, Tohoku University (Japan), 2012 - 2013
  • Ph.D., Tohoku University (Japan), 2012
  • M.D., Shimane University, 2004

Publications

Carota, IA, Kenig-Kozlovsky, Y, Onay, T, Scott, R, Thomson, BR, Souma, T, Bartlett, CS, Li, Y, Procissi, D, Ramirez, V, Yamaguchi, S, Tarjus, A, Tanna, CE, Li, C, Eremina, V, Vestweber, D, Oladipupo, SS, Breyer, MD, and Quaggin, SE. "Targeting VE-PTP phosphatase protects the kidney from diabetic injury." The Journal of Experimental Medicine 216, no. 4 (April 2019): 936-949.

PMID
30886059
Full Text

Ide, S, Finer, G, Maezawa, Y, Onay, T, Souma, T, Scott, R, Ide, K, Akimoto, Y, Li, C, Ye, M, Zhao, X, Baba, Y, Minamizuka, T, Jin, J, Takemoto, M, Yokote, K, and Quaggin, SE. "Transcription Factor 21 Is Required for Branching Morphogenesis and Regulates the Gdnf-Axis in Kidney Development." Journal of the American Society of Nephrology : Jasn 29, no. 12 (December 2018): 2795-2808.

PMID
30377232
Full Text

Stanifer, JW, Stapleton, HM, Souma, T, Wittmer, A, Zhao, X, and Boulware, LE. "Perfluorinated Chemicals as Emerging Environmental Threats to Kidney Health: A Scoping Review." Clinical Journal of the American Society of Nephrology : Cjasn 13, no. 10 (October 2018): 1479-1492.

PMID
30213782
Full Text

Liu, P, Wysocki, J, Souma, T, Ye, M, Ramirez, V, Zhou, B, Wilsbacher, LD, Quaggin, SE, Batlle, D, and Jin, J. "Novel ACE2-Fc chimeric fusion provides long-lasting hypertension control and organ protection in mouse models of systemic renin angiotensin system activation." Kidney International 94, no. 1 (July 2018): 114-125.

PMID
29691064
Full Text

Strausser, SA, Nakano, D, and Souma, T. "Acute kidney injury to chronic kidney disease transition: insufficient cellular stress response." Current Opinion in Nephrology and Hypertension 27, no. 4 (July 2018): 314-322. (Review)

PMID
29702491
Full Text

Souma, T, Thomson, BR, Heinen, S, Carota, IA, Yamaguchi, S, Onay, T, Liu, P, Ghosh, AK, Li, C, Eremina, V, Hong, Y-K, Economides, AN, Vestweber, D, Peters, KG, Jin, J, and Quaggin, SE. "Context-dependent functions of angiopoietin 2 are determined by the endothelial phosphatase VEPTP." Proceedings of the National Academy of Sciences of the United States of America 115, no. 6 (February 2018): 1298-1303.

PMID
29358379
Full Text

Thomson, BR, Souma, T, Tompson, SW, Onay, T, Kizhatil, K, Siggs, OM, Feng, L, Whisenhunt, KN, Yanovitch, TL, Kalaydjieva, L, Azmanov, DN, Finzi, S, Tanna, CE, Hewitt, AW, Mackey, DA, Bradfield, YS, Souzeau, E, Javadiyan, S, Wiggs, JL, Pasutto, F, Liu, X, John, SW, Craig, JE, Jin, J, Young, TL, and Quaggin, SE. "Angiopoietin-1 is required for Schlemm's canal development in mice and humans." The Journal of Clinical Investigation 127, no. 12 (December 2017): 4421-4436.

PMID
29106382
Full Text

Liu, P, Souma, T, Wei, AZ-S, Xie, X, Luo, X, and Jin, J. "Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation." Journal of visualized experiments : JoVE, no. 127 (September 6, 2017).

PMID
28930983
Full Text

Bailey, JC, Gharahkhani, P, Tompson, SW, Souma, T, Siggs, O, Young, TL, Tanna, AP, Pasquale, LR, Quaggin, SE, MacGregor, S, Craig, JE, Haines, JL, and Wiggs, JL. "Association of ANGPT1 with Primary Open Angle Glaucoma." Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO). Baltimore, MD. May 7, 2017 - May 11, 2017.: ASSOC RESEARCH VISION OPHTHALMOLOGY INC, June 1, 2017.

Scholars@Duke

Nezu, M, Souma, T, Yu, L, Sekine, H, Takahashi, N, Wei, AZ-S, Ito, S, Fukamizu, A, Zsengeller, ZK, Nakamura, T, Hozawa, A, Karumanchi, SA, Suzuki, N, and Yamamoto, M. "Nrf2 inactivation enhances placental angiogenesis in a preeclampsia mouse model and improves maternal and fetal outcomes." Science Signaling 10, no. 479 (May 16, 2017).

PMID
28512147
Full Text

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