Tomokazu Souma, MD, PhD

Medical Instructor in the Department of Medicine
Affiliate of the Regeneration Next Initiative
Email address tomokazu.souma@duke.edu

Education and Training

  • Post-doctoral Fellowship, Feinberg Cardiovascular Research Institute, Northwestern University, 2013 - 2014
  • Post-doctoral Fellowship, Department Of Medical Biochemistry, Tohoku University (Japan), 2012 - 2013
  • Ph.D., Tohoku University (Japan), 2012
  • M.D., Shimane University, 2004

Publications

Carota, Isabel A., Yael Kenig-Kozlovsky, Tuncer Onay, Rizaldy Scott, Benjamin R. Thomson, Tomokazu Souma, Christina S. Bartlett, et al. “Targeting VE-PTP phosphatase protects the kidney from diabetic injury..” J Exp Med 216, no. 4 (April 1, 2019): 936–49. https://doi.org/10.1084/jem.20180009.

PMID
30886059
Full Text

Ide, Shintaro, Gal Finer, Yoshiro Maezawa, Tuncer Onay, Tomokazu Souma, Rizaldy Scott, Kana Ide, et al. “Transcription Factor 21 Is Required for Branching Morphogenesis and Regulates the Gdnf-Axis in Kidney Development..” J Am Soc Nephrol 29, no. 12 (December 2018): 2795–2808. https://doi.org/10.1681/ASN.2017121278.

PMID
30377232
Full Text

Stanifer, John W., Heather M. Stapleton, Tomokazu Souma, Ashley Wittmer, Xinlu Zhao, and L Ebony Boulware. “Perfluorinated Chemicals as Emerging Environmental Threats to Kidney Health: A Scoping Review..” Clin J Am Soc Nephrol 13, no. 10 (October 8, 2018): 1479–92. https://doi.org/10.2215/CJN.04670418.

PMID
30213782
Full Text

Liu, Pan, Jan Wysocki, Tomokazu Souma, Minghao Ye, Veronica Ramirez, Bisheng Zhou, Lisa D. Wilsbacher, Susan E. Quaggin, Daniel Batlle, and Jing Jin. “Novel ACE2-Fc chimeric fusion provides long-lasting hypertension control and organ protection in mouse models of systemic renin angiotensin system activation..” Kidney Int 94, no. 1 (July 2018): 114–25. https://doi.org/10.1016/j.kint.2018.01.029.

PMID
29691064
Full Text

Strausser, Sarah A., Daisuke Nakano, and Tomokazu Souma. “Acute kidney injury to chronic kidney disease transition: insufficient cellular stress response..” Curr Opin Nephrol Hypertens 27, no. 4 (July 2018): 314–22. https://doi.org/10.1097/MNH.0000000000000424.

PMID
29702491
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Souma, Tomokazu, Benjamin R. Thomson, Stefan Heinen, Isabel Anna Carota, Shinji Yamaguchi, Tuncer Onay, Pan Liu, et al. “Context-dependent functions of angiopoietin 2 are determined by the endothelial phosphatase VEPTP..” Proc Natl Acad Sci U S A 115, no. 6 (February 6, 2018): 1298–1303. https://doi.org/10.1073/pnas.1714446115.

PMID
29358379
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Thomson, Benjamin R., Tomokazu Souma, Stuart W. Tompson, Tuncer Onay, Krishnakumar Kizhatil, Owen M. Siggs, Liang Feng, et al. “Angiopoietin-1 is required for Schlemm's canal development in mice and humans..” J Clin Invest 127, no. 12 (December 1, 2017): 4421–36. https://doi.org/10.1172/JCI95545.

PMID
29106382
Full Text

Liu, Pan, Tomokazu Souma, Andrew Zu-Sern Wei, Xueying Xie, Xunrong Luo, and Jing Jin. “Personalized Peptide Arrays for Detection of HLA Alloantibodies in Organ Transplantation..” J Vis Exp, no. 127 (September 6, 2017). https://doi.org/10.3791/56278.

PMID
28930983
Full Text

Bailey, Jessica Cooke, Puya Gharahkhani, Stuart W. Tompson, Tomokazu Souma, Owen Siggs, Terri L. Young, Angelo P. Tanna, et al. “Association of ANGPT1 with Primary Open Angle Glaucoma.” In Investigative Ophthalmology & Visual Science, Vol. 58. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2017.

Scholars@Duke

Nezu, Masahiro, Tomokazu Souma, Lei Yu, Hiroki Sekine, Nobuyuki Takahashi, Andrew Zu-Sern Wei, Sadayoshi Ito, et al. “Nrf2 inactivation enhances placental angiogenesis in a preeclampsia mouse model and improves maternal and fetal outcomes..” Sci Signal 10, no. 479 (May 16, 2017). https://doi.org/10.1126/scisignal.aam5711.

PMID
28512147
Full Text

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