Virginia Byers Kraus, MD, PhD

Professor of Medicine
Professor of Pathology
Professor in Orthopaedic Surgery
Member of Duke Molecular Physiology Institute
Affiliate of the Regeneration Next Initiative
Campus mail 300 N Duke St, Carmichael Building Room 15-205, Durham, NC 27701-2047
Phone (919) 681-6652
Email address kraus004@duke.edu

My special area of expertise is as a clinician scientist investigating osteoarthritis. Osteoarthritis is the most common form of joint disease in man and its incidence increases with age. It is a problem of increasing concern to the medical community due to the increasing longevity of the population. Trained as a molecular biologist and a Rheumatologist, I endeavor to study this disease from bedside to bench.

The work in this laboratory focuses on osteoarthritis and deals with the mechanisms of joint damage, and the discovery, validation and qualification of novel biochemical and genetic biomarkers for minimally invasive means of diagnosing disease, for predicting progression of disease, and for monitoring disease progression and response to therapy.

Education and Training

  • Fellow in Rheumatology, Medicine, Duke University, 1986 - 1989
  • Medical Resident, Medicine, Duke University, 1983 - 1986
  • Ph.D., Duke University, 1993
  • M.D., Duke University, 1982

Publications

Baht, Gurpreet S., Akshay Bareja, David E. Lee, Rajesh R. Rao, Rong Huang, Janet L. Huebner, David B. Bartlett, et al. “Author Correction: Meteorin-like facilitates skeletal muscle repair through a Stat3/IGF-1 mechanism.” Nat Metab 2, no. 8 (August 2020): 794. https://doi.org/10.1038/s42255-020-0257-y.

PMID
32694832
Full Text

Chou, Ching-Heng, Vaibhav Jain, Jason Gibson, David E. Attarian, Collin A. Haraden, Christopher B. Yohn, Remi-Martin Laberge, Simon Gregory, and Virginia B. Kraus. “Synovial cell cross-talk with cartilage plays a major role in the pathogenesis of osteoarthritis.” Sci Rep 10, no. 1 (July 2, 2020): 10868. https://doi.org/10.1038/s41598-020-67730-y.

PMID
32616761
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King, John D., Grant Rowland, Alejandro G. Villasante Tezanos, James Warwick, Virginia B. Kraus, Christian Lattermann, and Cale A. Jacobs. “Joint Fluid Proteome after Anterior Cruciate Ligament Rupture Reflects an Acute Posttraumatic Inflammatory and Chondrodegenerative State.” Cartilage 11, no. 3 (July 2020): 329–37. https://doi.org/10.1177/1947603518790009.

PMID
30033738
Full Text

Goode, Adam P., Rebecca J. Cleveland, Steven Z. George, Virginia B. Kraus, Todd A. Schwartz, Richard H. Gracely, Joanne M. Jordan, and Yvonne M. Golightly. “Different Phenotypes of Osteoarthritis in the Lumbar Spine Reflected by Demographic and Clinical Characteristics: The Johnston County Osteoarthritis Project.” In Arthritis Care Res (Hoboken), 72:974–81, 2020. https://doi.org/10.1002/acr.23918.

PMID
31058435
Full Text

Lv, Yuebin, Virginia Byers Kraus, Xiang Gao, Zhaoxue Yin, Jinhui Zhou, Chen Mao, Jun Duan, et al. “Higher dietary diversity scores and protein-rich food consumption were associated with lower risk of all-cause mortality in the oldest old.” Clin Nutr 39, no. 7 (July 2020): 2246–54. https://doi.org/10.1016/j.clnu.2019.10.012.

PMID
31685303
Full Text

Li, Zhi-Hao, Qing Chen, Virginia Byers Kraus, Dong Shen, Xi-Ru Zhang, Pei-Dong Zhang, Wen-Fang Zhong, et al. “Leisure activities and disability in activities of daily living among the oldest-old Chinese population: evidence from the Chinese Longitudinal Healthy Longevity Study.” Aging (Albany Ny) 12, no. 11 (June 12, 2020): 10687–703. https://doi.org/10.18632/aging.103287.

PMID
32532929
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Li, Zhi-Hao, Xiang Gao, Vincent Ch Chung, Wen-Fang Zhong, Qi Fu, Yue-Bin Lv, Zheng-He Wang, et al. “Associations of regular glucosamine use with all-cause and cause-specific mortality: a large prospective cohort study.” Ann Rheum Dis 79, no. 6 (June 2020): 829–36. https://doi.org/10.1136/annrheumdis-2020-217176.

PMID
32253185
Full Text

Zhou, Jinhui, Yuebin Lv, Chen Mao, Jun Duan, Xiang Gao, Jiaonan Wang, Zhaoxue Yin, et al. “Development and Validation of a Nomogram for Predicting the 6-Year Risk of Cognitive Impairment Among Chinese Older Adults.” J Am Med Dir Assoc 21, no. 6 (June 2020): 864-871.e6. https://doi.org/10.1016/j.jamda.2020.03.032.

PMID
32507532
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Wang, Jiaonan, Tiantian Li, Yuebin Lv, Virginia Byers Kraus, Yi Zhang, Chen Mao, Zhaoxue Yin, et al. “Fine Particulate Matter and Poor Cognitive Function among Chinese Older Adults: Evidence from a Community-Based, 12-Year Prospective Cohort Study.” Environ Health Perspect 128, no. 6 (June 2020): 67013. https://doi.org/10.1289/EHP5304.

PMID
32551881
Full Text

Zhang, Yi, Tiantian Li, Runmei Ma, Zhaoxue Yin, Jiaonan Wang, Mike Z. He, Dandan Xu, et al. “Long-term exposure to ambient fine particulate matter and fasting blood glucose level in a Chinese elderly cohort.” Sci Total Environ 717 (May 15, 2020): 137191. https://doi.org/10.1016/j.scitotenv.2020.137191.

PMID
32062280
Full Text

Pages