Virginia Byers Kraus, MD, PhD

Professor of Medicine
Professor of Pathology
Professor in Orthopaedic Surgery
Member of Duke Molecular Physiology Institute
Affiliate of the Regeneration Next Initiative
Campus mail 300 N Duke St, Carmichael Building Room 15-205, Durham, NC 27701-2047
Phone (919) 681-6652
Email address kraus004@duke.edu

My special area of expertise is as a clinician scientist investigating osteoarthritis. Osteoarthritis is the most common form of joint disease in man and its incidence increases with age. It is a problem of increasing concern to the medical community due to the increasing longevity of the population. Trained as a molecular biologist and a Rheumatologist, I endeavor to study this disease from bedside to bench.

The work in this laboratory focuses on osteoarthritis and deals with the mechanisms of joint damage, and the discovery, validation and qualification of novel biochemical and genetic biomarkers for minimally invasive means of diagnosing disease, for predicting progression of disease, and for monitoring disease progression and response to therapy.

Education and Training

  • Fellow in Rheumatology, Medicine, Duke University, 1986 - 1989
  • Medical Resident, Medicine, Duke University, 1983 - 1986
  • Ph.D., Duke University, 1993
  • M.D., Duke University, 1982

Publications

Zhang, Yi, Tiantian Li, Runmei Ma, Zhaoxue Yin, Jiaonan Wang, Mike Z. He, Dandan Xu, et al. “Long-term exposure to ambient fine particulate matter and fasting blood glucose level in a Chinese elderly cohort.” Sci Total Environ 717 (May 15, 2020): 137191. https://doi.org/10.1016/j.scitotenv.2020.137191.

PMID
32062280
Full Text

Lv, Yuebin, Jinhui Zhou, Virginia Byers Kraus, Tiantian Li, Jeremy A. Sarnat, Jiaonan Wang, Yang Liu, et al. “Long-term exposure to PM2.5 and incidence of disability in activities of daily living among oldest old.” Environ Pollut 259 (April 2020): 113910. https://doi.org/10.1016/j.envpol.2020.113910.

PMID
32023791
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Huang, ZeYu, Jing Chen, BoLei Li, Benhua Zeng, Ching-Heng Chou, Xin Zheng, JingWei Xie, et al. “Faecal microbiota transplantation from metabolically compromised human donors accelerates osteoarthritis in mice.” Ann Rheum Dis, March 23, 2020. https://doi.org/10.1136/annrheumdis-2019-216471.

PMID
32205337
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Spil, W. E. van, S. M. A. Bierma-Zeinstra, L. A. Deveza, N. K. Arden, A. -. C. Bay-Jensen, V Byers Kraus, L. Carlesso, et al. “A consensus-based framework for conducting and reporting osteoarthritis phenotype research.” Arthritis Res Ther 22, no. 1 (March 20, 2020): 54. https://doi.org/10.1186/s13075-020-2143-0.

PMID
32192519
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Mao, Chen, Zhi-Hao Li, Yue-Bin Lv, Xiang Gao, Virginia Byers Kraus, Jin-Hui Zhou, Xian-Bo Wu, et al. “Specific Leisure Activities and Cognitive Functions Among the Oldest-Old: The Chinese Longitudinal Healthy Longevity Survey.” J Gerontol a Biol Sci Med Sci 75, no. 4 (March 9, 2020): 739–46. https://doi.org/10.1093/gerona/glz086.

PMID
30946444
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Li, Zhi-Hao, Wen-Fang Zhong, Simin Liu, Virginia Byers Kraus, Yu-Jie Zhang, Xiang Gao, Yue-Bin Lv, et al. “Associations of habitual fish oil supplementation with cardiovascular outcomes and all cause mortality: evidence from a large population based cohort study.” Bmj 368 (March 4, 2020): m456. https://doi.org/10.1136/bmj.m456.

PMID
32131999
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Baht, G. S., A. Bareja, D. E. Lee, R. R. Rao, R. Huang, J. L. Huebner, D. B. Bartlett, et al. “Meteorin-like facilitates skeletal muscle repair through a Stat3/IGF-1 mechanism.” Nature Metabolism 2, no. 3 (March 1, 2020): 278–89. https://doi.org/10.1038/s42255-020-0184-y.

Full Text

Jacobs, Cale A., Emily R. Hunt, Caitlin E-W Conley, Darren L. Johnson, Austin V. Stone, Janet L. Huebner, Virginia B. Kraus, and Christian Lattermann. “Dysregulated Inflammatory Response Related to Cartilage Degradation after ACL Injury.” Med Sci Sports Exerc 52, no. 3 (March 2020): 535–41. https://doi.org/10.1249/MSS.0000000000002161.

PMID
31524832
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Hsueh, M. -. F., M. P. Bolognesi, S. S. Wellman, and V. B. Kraus. “Anti-inflammatory effects of naproxen sodium on human osteoarthritis synovial fluid immune cells.” Osteoarthritis Cartilage, February 4, 2020. https://doi.org/10.1016/j.joca.2020.01.013.

PMID
32028022
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Duan, Jun, Yue-Bin Lv, Xiang Gao, Jin-Hui Zhou, Virginia Byers Kraus, Yi Zeng, Hong Su, and Xiao-Ming Shi. “Association of cognitive impairment and elderly mortality: differences between two cohorts ascertained 6-years apart in China.” Bmc Geriatr 20, no. 1 (January 28, 2020): 29. https://doi.org/10.1186/s12877-020-1424-4.

PMID
31992221
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Pages