Virginia Byers Kraus, MD, PhD

Professor of Medicine
Professor of Pathology
Professor in Orthopaedic Surgery
Member of Duke Molecular Physiology Institute
Affiliate of the Regeneration Next Initiative
Campus mail 300 N Duke St, Carmichael Building Room 15-205, Durham, NC 27701-2047
Phone (919) 681-6652
Email address kraus004@duke.edu

My special area of expertise is as a clinician scientist investigating osteoarthritis. Osteoarthritis is the most common form of joint disease in man and its incidence increases with age. It is a problem of increasing concern to the medical community due to the increasing longevity of the population. Trained as a molecular biologist and a Rheumatologist, I endeavor to study this disease from bedside to bench.

The work in this laboratory focuses on osteoarthritis and deals with the mechanisms of joint damage, and the discovery, validation and qualification of novel biochemical and genetic biomarkers for minimally invasive means of diagnosing disease, for predicting progression of disease, and for monitoring disease progression and response to therapy.

Education and Training

  • Fellow in Rheumatology, Medicine, Duke University, 1986 - 1989
  • Medical Resident, Medicine, Duke University, 1983 - 1986
  • Ph.D., Duke University, 1993
  • M.D., Duke University, 1982

Publications

Kimmerling, Kelly A., Sara J. Oswald, Janet L. Huebner, Dianne Little, Virginia B. Kraus, Jing X. Kang, Chia-Lung Wu, and Farshid Guilak. “Transgenic conversion of ω-6 to ω-3 polyunsaturated fatty acids via fat-1 reduces the severity of post-traumatic osteoarthritis.” Arthritis Res Ther 22, no. 1 (April 15, 2020): 83. https://doi.org/10.1186/s13075-020-02170-7.

PMID
32295649
Full Text

Yuan, Jin-Qiu, Yue-Bin Lv, Virginia Byers Kraus, Xiang Gao, Zhao-Xue Yin, Hua-Shuai Chen, Jie-Si Luo, Yi Zeng, Chen Mao, and Xiao-Ming Shi. “Number of natural teeth, denture use and mortality in Chinese elderly: a population-based prospective cohort study.” Bmc Oral Health 20, no. 1 (April 10, 2020): 100. https://doi.org/10.1186/s12903-020-01084-9.

PMID
32276615
Full Text

Hsueh, M. -. F., S. Wellman, M. Bolognesi, and V. B. Kraus. “FOLATE RECEPTOR POSITIVE MACROPHAGES OF OSTEOARTHRITIC SYNOVIAL FLUID ARE HIGH PRODUCERS OF IL-1 beta.” In Osteoarthritis and Cartilage, 28:S108–9. ELSEVIER SCI LTD, 2020.

Scholars@Duke

Lv, Yuebin, Jinhui Zhou, Virginia Byers Kraus, Tiantian Li, Jeremy A. Sarnat, Jiaonan Wang, Yang Liu, et al. “Long-term exposure to PM2.5 and incidence of disability in activities of daily living among oldest old.” Environ Pollut 259 (April 2020): 113910. https://doi.org/10.1016/j.envpol.2020.113910.

PMID
32023791
Full Text

Spil, W. E. van, S. M. A. Bierma-Zeinstra, L. A. Deveza, N. K. Arden, A. -. C. Bay-Jensen, V Byers Kraus, L. Carlesso, et al. “A consensus-based framework for conducting and reporting osteoarthritis phenotype research.” Arthritis Res Ther 22, no. 1 (March 20, 2020): 54. https://doi.org/10.1186/s13075-020-2143-0.

PMID
32192519
Full Text

Mao, Chen, Zhi-Hao Li, Yue-Bin Lv, Xiang Gao, Virginia Byers Kraus, Jin-Hui Zhou, Xian-Bo Wu, et al. “Specific Leisure Activities and Cognitive Functions Among the Oldest-Old: The Chinese Longitudinal Healthy Longevity Survey.” J Gerontol a Biol Sci Med Sci 75, no. 4 (March 9, 2020): 739–46. https://doi.org/10.1093/gerona/glz086.

PMID
30946444
Full Text

Li, Zhi-Hao, Wen-Fang Zhong, Simin Liu, Virginia Byers Kraus, Yu-Jie Zhang, Xiang Gao, Yue-Bin Lv, et al. “Associations of habitual fish oil supplementation with cardiovascular outcomes and all cause mortality: evidence from a large population based cohort study.” Bmj 368 (March 4, 2020): m456. https://doi.org/10.1136/bmj.m456.

PMID
32131999
Full Text

Baht, G. S., A. Bareja, D. E. Lee, R. R. Rao, R. Huang, J. L. Huebner, D. B. Bartlett, et al. “Meteorin-like facilitates skeletal muscle repair through a Stat3/IGF-1 mechanism.” Nature Metabolism 2, no. 3 (March 1, 2020): 278–89. https://doi.org/10.1038/s42255-020-0184-y.

Full Text

Jacobs, Cale A., Emily R. Hunt, Caitlin E-W Conley, Darren L. Johnson, Austin V. Stone, Janet L. Huebner, Virginia B. Kraus, and Christian Lattermann. “Dysregulated Inflammatory Response Related to Cartilage Degradation after ACL Injury.” Med Sci Sports Exerc 52, no. 3 (March 2020): 535–41. https://doi.org/10.1249/MSS.0000000000002161.

PMID
31524832
Full Text

Duan, Jun, Yue-Bin Lv, Xiang Gao, Jin-Hui Zhou, Virginia Byers Kraus, Yi Zeng, Hong Su, and Xiao-Ming Shi. “Association of cognitive impairment and elderly mortality: differences between two cohorts ascertained 6-years apart in China.” Bmc Geriatr 20, no. 1 (January 28, 2020): 29. https://doi.org/10.1186/s12877-020-1424-4.

PMID
31992221
Full Text

Pages