Virginia Byers Kraus, MD, PhD

Professor of Medicine
Professor of Pathology
Professor in Orthopaedic Surgery
Member of Duke Molecular Physiology Institute
Affiliate of the Regeneration Next Initiative
Campus mail 300 N Duke St, Carmichael Building Room 15-205, Durham, NC 27701-2047
Phone (919) 681-6652
Email address kraus004@duke.edu

My special area of expertise is as a clinician scientist investigating osteoarthritis. Osteoarthritis is the most common form of joint disease in man and its incidence increases with age. It is a problem of increasing concern to the medical community due to the increasing longevity of the population. Trained as a molecular biologist and a Rheumatologist, I endeavor to study this disease from bedside to bench.

The work in this laboratory focuses on osteoarthritis and deals with the mechanisms of joint damage, and the discovery, validation and qualification of novel biochemical and genetic biomarkers for minimally invasive means of diagnosing disease, for predicting progression of disease, and for monitoring disease progression and response to therapy.

Education and Training

  • Fellow in Rheumatology, Medicine, Duke University, 1986 - 1989
  • Medical Resident, Medicine, Duke University, 1983 - 1986
  • Ph.D., Duke University, 1993
  • M.D., Duke University, 1982

Publications

Andonian, BJ, Chou, C-H, Kraus, VB, Kraus, WE, and Huffman, KM. "Plasma Mir-146a-5p Associates with Beneficial Body Composition and Plasma Metabolic Profiles in Rheumatoid Arthritis.": WILEY, September 1, 2018.

Scholars@Duke

Andonian, BJ, Chou, C-H, Kraus, VB, Kraus, WE, and Huffman, KM. "Plasma Mir-146a-5p Associates with Beneficial Body Composition and Plasma Metabolic Profiles in Rheumatoid Arthritis.": WILEY, September 1, 2018.

Scholars@Duke

Golightly, YM, Nocera, M, Beutler, AI, Renner, JB, Guermazi, A, Cantrell, J, Padua, DA, Cameron, KL, Svoboda, SJ, Jordan, JM, Loeser, R, Callahan, LF, Kraus, VB, Lohmander, LS, and Marshall, SW. "Association of Knee Ligament and/or Meniscal Injury with Radiographic Knee Osteoarthritis in Military Officers.": WILEY, September 1, 2018.

Scholars@Duke

Golightly, YM, Nocera, M, Beutler, AI, Renner, JB, Guermazi, A, Cantrell, J, Padua, DA, Cameron, KL, Svoboda, SJ, Jordan, JM, Loeser, R, Callahan, LF, Kraus, VB, Lohmander, LS, and Marshall, SW. "Association of Knee Ligament and/or Meniscal Injury with Radiographic Knee Osteoarthritis in Military Officers.": WILEY, September 1, 2018.

Scholars@Duke

Longobardi, L, Jordan, JM, Shi, XA, Renner, JB, Schwartz, TA, Nelson, AE, Barrow, DA, Kraus, VB, and Spagnoli, A. "Associations between the chemokine biomarker CCL2 and knee osteoarthritis outcomes: the Johnston County Osteoarthritis Project." Osteoarthritis and Cartilage 26, no. 9 (September 2018): 1257-1261.

PMID
29723633
Full Text

Huang, Z, Huang, C, Xie, J, Ma, J, Cao, G, Huang, Q, Shen, B, Byers Kraus, V, and Pei, F. "Analysis of a large data set to identify predictors of blood transfusion in primary total hip and knee arthroplasty." Transfusion 58, no. 8 (August 25, 2018): 1855-1862.

PMID
30145838
Full Text

Lv, Y-B, Liu, S, Yin, Z-X, Gao, X, Kraus, VB, Mao, C, Yuan, J-Q, Zhang, J, Luo, J-S, Chen, H-S, Zeng, Y, and Shi, X-M. "Associations of Body Mass Index and Waist Circumference with 3-Year All-Cause Mortality Among the Oldest Old: Evidence from a Chinese Community-Based Prospective Cohort Study." Journal of the American Medical Directors Association 19, no. 8 (August 2018): 672-678.e4.

PMID
29807748
Full Text

Zuo, X, Luciano, A, Pieper, CF, Bain, JR, Kraus, VB, Kraus, WE, Morey, MC, and Cohen, HJ. "Combined Inflammation and Metabolism Biomarker Indices of Robust and Impaired Physical Function in Older Adults." Journal of the American Geriatrics Society 66, no. 7 (July 2018): 1353-1359.

PMID
29738072
Full Text

King, JD, Rowland, G, Villasante Tezanos, AG, Warwick, J, Kraus, VB, Lattermann, C, and Jacobs, CA. "Joint Fluid Proteome after Anterior Cruciate Ligament Rupture Reflects an Acute Posttraumatic Inflammatory and Chondrodegenerative State." Cartilage (July 2018): 1947603518790009-null.

PMID
30033738
Full Text

Golightly, YM, Hannan, MT, Nelson, AE, Hillstrom, HJ, Cleveland, RJ, Kraus, VB, Schwartz, TA, Goode, AP, Flowers, P, Renner, JB, and Jordan, JM. "Relationship of Joint Hypermobility with Ankle and Foot Radiographic Osteoarthritis and Symptoms in a Community-Based Cohort." Arthritis Care & Research (June 28, 2018).

PMID
29953742
Full Text

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