Virginia Byers Kraus, MD, PhD

Professor of Medicine
Professor of Pathology
Professor in Orthopaedic Surgery
Member of Duke Molecular Physiology Institute
Affiliate of the Regeneration Next Initiative
Campus mail 300 N Duke St, Carmichael Building Room 15-205, Durham, NC 27701-2047
Phone (919) 681-6652
Email address kraus004@duke.edu

My special area of expertise is as a clinician scientist investigating osteoarthritis. Osteoarthritis is the most common form of joint disease in man and its incidence increases with age. It is a problem of increasing concern to the medical community due to the increasing longevity of the population. Trained as a molecular biologist and a Rheumatologist, I endeavor to study this disease from bedside to bench.

The work in this laboratory focuses on osteoarthritis and deals with the mechanisms of joint damage, and the discovery, validation and qualification of novel biochemical and genetic biomarkers for minimally invasive means of diagnosing disease, for predicting progression of disease, and for monitoring disease progression and response to therapy.

Education and Training

  • Fellow in Rheumatology, Medicine, Duke University, 1986 - 1989
  • Medical Resident, Medicine, Duke University, 1983 - 1986
  • Ph.D., Duke University, 1993
  • M.D., Duke University, 1982

Publications

Yuan, Jin-Qiu, Yue-Bin Lv, Virginia Byers Kraus, Xiang Gao, Zhao-Xue Yin, Hua-Shuai Chen, Jie-Si Luo, Yi Zeng, Chen Mao, and Xiaoming Shi. “Denture Use Protects Against All-Cause Mortality Associated with Tooth Loss in Older Adults,” September 29, 2018.

Scholars@Duke

Lv, Yue-Bin, Jin-Qiu Yuan, Chen Mao, Xiang Gao, Zhao-Xue Yin, Virginia Byers Kraus, Jie-Si Luo, et al. “Association of Body Mass Index With Disability in Activities of Daily Living Among Chinese Adults 80 Years of Age or Older..” Jama Netw Open 1, no. 5 (September 7, 2018). https://doi.org/10.1001/jamanetworkopen.2018.1915.

PMID
30646143
Full Text

Andonian, Brian J., Ching-Heng Chou, Virginia B. Kraus, William E. Kraus, and Kim M. Huffman. “Plasma Mir-146a-5p Associates with Beneficial Body Composition and Plasma Metabolic Profiles in Rheumatoid Arthritis.” In Arthritis & Rheumatology, Vol. 70. WILEY, 2018.

Scholars@Duke

Golightly, Yvonne M., Maryalice Nocera, Anthony I. Beutler, Jordan B. Renner, Ali Guermazi, John Cantrell, Darin A. Padua, et al. “Association of Knee Ligament and/or Meniscal Injury with Radiographic Knee Osteoarthritis in Military Officers.” In Arthritis & Rheumatology, Vol. 70. WILEY, 2018.

Scholars@Duke

Longobardi, L., J. M. Jordan, X. A. Shi, J. B. Renner, T. A. Schwartz, A. E. Nelson, D. A. Barrow, V. B. Kraus, and A. Spagnoli. “Associations between the chemokine biomarker CCL2 and knee osteoarthritis outcomes: the Johnston County Osteoarthritis Project..” Osteoarthritis Cartilage 26, no. 9 (September 2018): 1257–61. https://doi.org/10.1016/j.joca.2018.04.012.

PMID
29723633
Full Text

Lv, Yue-Bin, Simin Liu, Zhao-Xue Yin, Xiang Gao, Virginia Byers Kraus, Chen Mao, Jin-Qiu Yuan, et al. “Associations of Body Mass Index and Waist Circumference with 3-Year All-Cause Mortality Among the Oldest Old: Evidence from a Chinese Community-Based Prospective Cohort Study..” J Am Med Dir Assoc 19, no. 8 (August 2018): 672-678.e4. https://doi.org/10.1016/j.jamda.2018.03.015.

PMID
29807748
Full Text

Huang, ZeYu, Cheng Huang, JinWei Xie, Jun Ma, GuoRui Cao, Qiang Huang, Bin Shen, Virginia Byers Kraus, and FuXing Pei. “Analysis of a large data set to identify predictors of blood transfusion in primary total hip and knee arthroplasty..” Transfusion 58, no. 8 (August 2018): 1855–62. https://doi.org/10.1111/trf.14783.

PMID
30145838
Full Text

King, John D., Grant Rowland, Alejandro G. Villasante Tezanos, James Warwick, Virginia B. Kraus, Christian Lattermann, and Cale A. Jacobs. “Joint Fluid Proteome after Anterior Cruciate Ligament Rupture Reflects an Acute Posttraumatic Inflammatory and Chondrodegenerative State..” Cartilage, July 1, 2018. https://doi.org/10.1177/1947603518790009.

PMID
30033738
Full Text

Zuo, Xintong, Alison Luciano, Carl F. Pieper, James R. Bain, Virginia B. Kraus, William E. Kraus, Miriam C. Morey, and Harvey J. Cohen. “Combined Inflammation and Metabolism Biomarker Indices of Robust and Impaired Physical Function in Older Adults..” J Am Geriatr Soc 66, no. 7 (July 2018): 1353–59. https://doi.org/10.1111/jgs.15393.

PMID
29738072
Full Text

Bartlett, David B., Leslie H. Willis, Cris A. Slentz, Andrew Hoselton, Leslie Kelly, Janet L. Huebner, Virginia B. Kraus, et al. “Ten weeks of high-intensity interval walk training is associated with reduced disease activity and improved innate immune function in older adults with rheumatoid arthritis: a pilot study..” Arthritis Res Ther 20, no. 1 (June 14, 2018). https://doi.org/10.1186/s13075-018-1624-x.

PMID
29898765
Full Text

Pages