New funding awards - April 2021

Sponsored Research

Geoffrey Ginsburg of Cardiology has received an award (5U01-HG010225-03S5) from the National Institutes of Health for a project entitled "The IGNITE II CC: Engagement, Coordination, Demonstration, and Dissemination." Total funding will be $296,034.

William Kraus of Cardiology has received an award (1R01-HL153497-01A1) from the National Institutes of Health for a project entitled "Skeletal Muscle Molecular Drug Targets for Exercise-induced Cardiometabolic Health." Total funding will be $3,081,020.

Robert Mentz of Cardiology has received an award from the Heart Failure Society of America for a project entitled "Journal of Cardiac Failure." Total funding will be $328,349.

Martin Moseley III of Cardiology has received an award (80NSSC21P0967) from the National Aeronautics and Space Administration for a project entitled "The Integrated Impact of Diet on Human Immune Response, the Gut Microbiota, and Nutritional Status During Adaptation to Spaceflight." Total funding will be $44,080.

Claudia Y. Lee (Mentor: Sudarshan Rajagopal) of Cardiology has received an award (1F31-HL152656-01A1) from the National Institutes of Health for a project entitled "National Research Service Award (F31)." Total funding will be $110,925.

Tracy Wang of Cardiology has received a sub-award (17FTF33661087) through the University of Pennsylvania for a project entitled "UPENN - ICU utilization for NSTEMI patients - Professional Society." Total funding will be $41,825.

Diana E. Soliman (Mentor: Matthew Crowley) of Endocrinology has received an award from the Endocrine Fellows Foundation for a project entitled "EFF Grant." Total funding will be $2,500.

Brian Sullivan of Gastroenterology has received an award from the American Gastroenterological Association for a project entitled "Post-colonoscopy Risk Stratification Based on Germline and Somatic Genetic Factors." Total funding will be $300,000.

Nicole Depasquale of General Internal Medicine has received an award (1K01-AG070284-01) from the National Institutes of Health for a project entitled "Supporting Patients and Family Care Partners to Manage Chronic Kidney Disease Together." Total funding will be $570,100.

Helen Tang (Mentor: Nelson Chao) of Hematologic Malignancies and Cellular Therapy has received an award from the American Society of Hematology for a project entitled "Personalized prebiotics to optimize microbiota metabolism and improve transplant outcomes(F)." Total funding will be $6,000.

John Strouse of Hematology has received an award from the American Society of Hematology for a project entitled "Central Carolinas Clinical Trials Collaboration (C3TC)." Total funding will be $100,000.

Susanna Naggie of Infectious Diseases has received a sub-award (2UM-1AI068636-15) through the University of California - Los Angeles for a project entitled "Leadership and Operations Center (LOC), Aids Clinical Trial Group (ACTG) HEP Committee Chair - Transformative Science Group." Total funding will be $56,740.

Jason Somarelli of Medical Oncology has received an award from the Henry David Thoreau Foundation for a project entitled "The Duke University Marine Laboratory Scholars Program: Enhancing mentored research experiences for undergraduates." Total funding will be $38,679.

Allison Ashley-Koch of Nephrology has received an award (1R21-DK124836-01A1) from the National Institutes of Health for a project entitled "Identifying novel clinical, genetic and proteomic risk factors for sickle cell nephropathy.." Total funding will be $442,750.

Patty Lee of Pulmonary has received an award (75N96021P00123) from the National Heart, Lung, and Blood Institute for a project entitled "Fixed Price Contract - Intramural Targeted Anti-COVID-19 program (ITAC) Harnessing the Extracellular Matrix to Treat COVID-19-Induced ARDS." Total funding will be $105,000.

Megan Clowse of Rheumatology has received a sub-award (W81XWH2010692) through the Northwestern University for a project entitled "EHR-based LongItudinal Cohort to Explore Pregnancy OuTComes in SLE (ELIPTCL)." Total funding will be $18,935.

Industry-sponsored Clinical Trials

Marat Fudim of Cardiology has received an award from BTG International Inc for a project entitled "Digoxin Toxicity Study." Total funding will be $227,932.

John Harrison of Cardiology has received an award from Boston Scientific Corporation for a project entitled "PROTECTED TAVR." Total funding will be $848,772.

Michel Khouri of Cardiology has received an award from Eidos Therapeutics for a project entitled "AG10 ATTR-CM R6MWT." Total funding will be $20,930.

Kristin Newby of Cardiology has received a sub-award (5R44-DK107080-05) through BioKier, Inc. for a project entitled "Development of an oral therapeutic to mimic the anti-diabetic effects of gastric bypass surgery." Total funding will be $100,000.

Neha Pagidipati of Cardiology has received an award from Boehringer Ingelheim Corporation for a project entitled "BI - CKD PHSR Study." Total funding will be $801,080.

Kishan Parikh of Cardiology has received an award from Clinetic, Inc for a project entitled "Pulmonary Hypertension Databank and Electronic Health Record Analysis." Total funding will be $158,271.

Jonathan Piccini of Cardiology has received an award from Medtronic, Inc. for a project entitled "DEFINE-AFIB." Total funding will be $81,951.

Sudarshan Rajagopal of Cardiology has received an award from Janssen Research & Development, LLC for a project entitled "AC-055-315 A Phase 3, Prospective, Multicenter, Double-blind, Double-Dummy, Randomized, Active-controlled, Parallel-group, Group-sequential, Adaptive, Event-Driven Study to compare Efficacy, Safety, and Tollerability of Macitentan 75mg Versus Maciten." Total funding will be $214,328.

Amy Barto of Gastroenterology has received an award from Rebiotix Inc. for a project entitled "A Phase 3 Open-Label Clinical Study to Evaluate the Safety and Tolerability of Rebiotix RBX2660 (microbiota suspension) in Subjects with Recurrent Clostridium difficile Infection." Total funding will be $91,133.

David Leiman of Gastroenterology has received an award from Arena Pharmaceuticals, Inc. for a project entitled "A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study to Assess the Safety and Efficacy of Etrasimod in Adult Subjects with Eosinophilic Esophagitis." Total funding will be $337,973.

Lindsay Rein of Hematologic Malignancies and Cellular Therapy has received an award from Incyte Corporation for a project entitled "A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of the Combination of PI3K? Inhibitor Parsaclisib and Ruxolitinib in Participants With Myelofibrosis." Total funding will be $440,267.

Marilyn Telen of Hematology has received an award from FORMA Therapeutics, Inc. for a project entitled "FORMA FT4202-Hem-301 PRAISE PTV. An Adaptive, Randomized, Placebo-controlled, Double-blind, Multi-center Study of Oral FT-4202, a Pyruvate Kinase Activator in Patients with Sickle Cell Disease (PRAISE).." Total funding will be $76,968.

Carey Anders of Medical Oncology has received an award from Caris Life Sciences for a project entitled "Retrospective tissue study HER2-positive breast cancer prediction of brain metastasis." Total funding will be $51,250.

April Salama of Medical Oncology has received an award from Merck Sharp & Dohme for a project entitled "A Phase 1/2 Open-Label Rolling-Arm Umbrella Platform Design of Investigational Agents With or Without Pembrolizumab or Pembrolizumab Alone in Participants with Melanoma (KEYNOTE-U02): Substudy 02A." Total funding will be $1,245,066.

April Salama of Medical Oncology has received an award from Merck Sharp & Dohme for a project entitled "A Phase 1/2 Open-Label Rolling-Arm Umbrella Platform Design of Investigational Agents With or Without Pembrolizumab or Pembrolizumab Alone in Participants With Melanoma (KEYMAKER-U02): Substudy 02B." Total funding will be $1,162,596.

April Salama of Medical Oncology has received an award from Nektar Therapeutics for a project entitled "A Phase 3, Randomized, Open-label Study to Compare Adjuvant Immunotherapy of Bempegaldesleukin Combined with Nivolumab Versus Nivolumab After Complete Resection of Melanoma in Patients at High Risk for Recurrence (PIVOT-12)." Total funding will be $237,611.

John Strickler of Medical Oncology has received an award from Daiichi Sankyo Inc for a project entitled "[DS8201-A-U207] A phase 2, multicenter, randomized study of trastuzumab deruxtecan in subjects with HER2-overexpressing locally advanced, unresectable or metastatic colorectal cancer (Destiny-CRC02)." Total funding will be $199,217.

Tian Zhang of Medical Oncology has received an award from Genentech, Inc. for a project entitled "A PHASE III, MULTICENTER, RANDOMIZED, OPEN-LABEL STUDY TO EVALUATE THE EFFICACY AND SAFETY OF ATEZOLIZUMAB GIVEN IN COMBINATION WITH CABOZANTINIB VERSUS CABOZANTINIB ALONE IN PATIENTS WITH INOPERABLE, LOCALLY ADVANCED, OR METASTATIC RENAL CELL CARCIN." Total funding will be $385,616.

Neil MacIntyre of Pulmonary has received an award from COPD Foundation Inc for a project entitled "COPD Foundation Agreement - Longitudinal Follow-Up to (1 of 2) Genetic Epidemiology of COPD." Total funding will be $1.

Momen Wahidi of Pulmonary has received an award from Veracyte, Inc. for a project entitled "Veracyte Atlas DHF 011-003 Evaluation of a biomarker test for the early molecular profiling of lung cancer utilizing cytological samples." Total funding will be $175,924.

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