Department of Medicine faculty have received notice of the following research, clinical trials, CME or other training awards.
[tabs style="vertical"][tab title="Sponsored research"]Ying Xian of Cardiology has received an award from the American Heart Association for a project entitled "Safety and Clinical Effectiveness of Intravenous Tissue Plasminogen Activator for Acute Ischemic Stroke." Total funding will be $153,947.
Yen Rei Yu (Mentor: Michael D. Gunn) of Cardiology has received an award from the Pulmonary Hypertension Association for a project entitled "The Role of Monocytes in Pulmonary Arterial Hypertension." Total funding will be $27,500.
Nelson J. Chao of Hematological Malignancies and Cellular Therapy has received a sub-award (#546-RITN-Amdt FY13) through the National Marrow Donor Program for a project entitled "RITN Agreement." Total funding will be $8,000.
Jason E. Stout of Infectious Diseases has received a sub-award (TBTC 10FED1007388-VA-FHI) through Family Health International for a project entitled "Tuberculosis Trial Consortium." Total funding will be $129,544.
Mythreye Karthikeyan of Medical Oncology has received an award from the Ovarian Cancer Research Fund, Inc. for a project entitled "Investigating the TGFЯ Superfamily as Therapeutic Targets in Ovarian Cancer." Total funding will be $450,000.
Victoria L. Seewaldt of Medical Oncology has received a sub-award (R01-CA170851-) through Tufts University for a project entitled "Mechanisms of breast cancer associated with obesity (PQ1)." Total funding will be $292,388.
Wolfgang B. Liedtke of Neurology has received an award from the North Carolina Biotechnology Center for a project entitled "Transdermal targeting of pathological pain by enhanced delivery vehicles." Total funding will be $100,000.
Burton L. Scott of Neurology has received an award (2U10-NS044453-11) from the National Institutes of Health for a project entitled "Parkinson's Disease Neuroprotection Clinical Trial." Total funding will be $90,391.
Loretta Que of Pulmonary, Allergy, and Critical Care Medicine has received an award (1R01-HL107590-01A1) from the National Institutes of Health for a project entitled "Modulation of Asthma by GSNO-based Therapies." Total funding will be $1,570,000.
Momen Wahidi of Pulmonary, Allergy, and Critical Care Medicine has received an award through Ohio State University for a project entitled "Ohio State PDT Registry." Total funding will be $51,250.
Lisa G. Criscione-Schreiber of Rheumatology and Immunology has received an award from the Rheumatology Research Foundation for a project entitled "RRF Amgen Fellowship Training Award FY 2014." Total funding will be $25,000.[/tab][tab title="Industry-sponsored clinical trials"]Robert M. Califf of Cardiology has received an award from Daiichi Sankyo Inc for a project entitled "Cancer and Thrombosis Think Tank." Total funding will be $15,000.
Christopher Granger of Cardiology has received an award from Takeda Pharmaceuticals North America Inc. for a project entitled "Data Monitoring Committee (DMC) Activities for Takeda's TAK-875 Program." Total funding will be $1,639,920.
Michael R. Klein (Mentor: Igor Klem) of Cardiology has received an award from Medtronic, Inc. for a project entitled "Cardiac MRI Risk Stratification for ICD Implantation." Total funding will be $100,000.
William E. Kraus of Cardiology has received an award from Liposcience Inc. for a project entitled "NMR-Derived Lipoprotein and Metabolite Analysis of Plasma obtained from Cathgen Participants."
Kenneth W. Mahaffey of Cardiology has received an award from Amgen, Inc. for a project entitled "Ajudication of Clinical Events for Amgen Study 20120103." Total funding will be $227,420.
Matthew T. Roe of Cardiology has received an award from the Sanofi-Aventis U.S. for a project entitled "EFC11570 CV Outcomes Study." Total funding will be $116,349,847.
Bimal R. Shah of Cardiology has received an award from Novartis Pharmaceuticals Corporation for a project entitled "Go To Duke." Total funding will be $60,000
John R. Guyton of Endocrinology, Metabolism, and Nutrition has received an award from Sanofi-Aventis U.S. for a project entitled "A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Evaluate the Efficacy and Safety of SAR236553/REGN727 in Patients With Heterozygous Familial Hypercholesterolemia and LDL-C higher or equal to 160mg/dL with Lipid-Modifying Thera." Total funding will be $78,390.
John R. Guyton of Endocrinology, Metabolism, and Nutrition has received an award from Sanofi-Aventis U.S. for a project entitled "A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Evaluate the Efficacy and Safety of SAR236553/REGN727 in Patients With Heterozygous Familial Hypercholesterolemia Not Adequately Controlled With Their Lipid-Modifying Therapy." Total funding will be $77,542.
Ziad F. Gellad of Gastroenterology has received an award from Pentax Medical Company for a project entitled "Pentax: Endoscopic Practice Management Network." Total funding will be $150,000.
Andrew J. Muir of Gastroenterology has received an award from Gilead Sciences, Inc. for a project entitled "HCV RNA Monitoring for Gilead's GS-US-337-0102 Protocol." Total funding will be $609,509.
Andrew J. Muir of Gastroenterology has received an award from Gilead Sciences, Inc. for a project entitled "HCV RNA Monitoring for Gilead's GS-US-334-0123 Protocol." Total funding will be $229,560.
Andrew J. Muir of Gastroenterology has received an award from Gilead Sciences, Inc. for a project entitled "HCV RNA Monitoring for Gilead's A Phase 3, Multicenter." Total funding will be $390,763.
Soko Setoguchi-Iwata of General Internal Medicine has received an award from Janssen Research & Development, LLC for a project entitled "Surveillance of Health Care in Asian Network (SCAN) Project: Infrastructure Development and Analysis with the Asian Pharmacoepidemiology Network." Total funding will be $1,357,377.
Cristina Gasparetto of Hematological Malignancies and Cellular Therapy has received an award from Osiris Therapeutics, Inc. for a project entitled "A Phase I/II Multi-center, Open Label, Dose Escalation, Safety and Pharmacokinetic Study of PRLX 93936 Administered Intravenously 3 Days a Week for 3 Weeks Followed by a 9 day rest period in pts with Relapsed or Relapsed/Refractort Mulitple Myeloma." Total funding will be $595,427.
Ara D. Metjian of Hematology has received an award from Daiichi Sankyo Inc for a project entitled "Daiichi eTRIS Study." Total funding will be $230,100.
Barbara D. Alexander of Infectious Diseases has received an award from Optimer Pharmaceuticals, Inc. for a project entitled "Phase 3b Multi-Center, Double-Blind, Randomized, Placebo Controlled Study to Demonstrate the Safety and Efficacy of Fidaxomicin for Prophylaxis against C. diff-assosciated Diarrhea in Individuals Undergoing Hematopoietic Stem Cell Transplanation." Total funding will be $331,752.
Mehri McKellar of Infectious Diseases has received an award from Gilead Sciences, Inc. for a project entitled "GS-US-236-0128, A Randomized, Double-blind Phase 3B Study to Evaluate the Safety and Efficacy of Elvitegravir/Cobicistat/Emtricitabine/TDF vs RTV-Boosted Atazanavir Plus Emtricitabine/TDFin HIV-1 Infected, ART-Naive Women." Total funding will be $155,238.
Jason E. Stout of Infectious Diseases has received an award from JHP Pharmaceuticals for a project entitled "Aplisol-04, nontuberculous mycobacteria study." Total funding will be $36,541.
Jason E. Stout of Infectious Diseases has received an award from the JHP Pharmaceuticals for a project entitled "JHP - Aplisol - 02." Total funding will be $58,852.
Cameron R. Wolfe of Infectious Diseases has received an award from Merck Sharp & Dohme for a project entitled "Solid Organ Transplantation and the Use of Raltegravir in HIV-Infected Patients: An Observational Study of Pharmaceuticals, Safety, Tolerability and Efficacy." Total funding will be $266,978.
Frank R. Dunphy II of Medical Oncology has received an award from Astex Therapeutics Ltd. for a project entitled "A study of HSP90 Inhibitor AT13387 alone and in combination with Crizotinib in the treatment of non-small cell lung cancer (NSCLC)." Total funding will be $125,405.
Michael R. Harrison of Medical Oncology has received an award from Bristol-Myers Squibb for a project entitled "A Randomized, Open-Label, Phase 3 Study of BMS-936558 vs. Everolimus in Subjects with Advanced or Metastatic Clear-Cell Renal Cell Carcinoma Who Have Received Prior Anti-Angiogenic Therapy." Total funding will be $205,853.
P. Kelly Marcom of Medical Oncology has received an award from Novartis Pharmaceuticals Corporation for a project entitled "Norvartis Breast Cancer Practicum." Total funding will be $64,740.
Andrew B. Nixon of Medical Oncology has received an award from Alliance for Clinical Trials in Oncology Foundation for a project entitled "Blood Based Biomarker profiling for CALGB 80405." Total funding will be $515,900.
April K. Salama of Medical Oncology has received an award from Genentech, Inc. for a project entitled "A phase III, randomized, double-blind, placebo-controlled study of Vemurafenib (RO5185426) adjuvant therapy i patients with surgically resected, cutaneous BRAF-Mutant melanoma at high risk for recurrence." Total funding will be $1,121,244.
April K. Salama of Medical Oncology has received an award from Bristol-Myers Squibb for a project entitled "A randomized, open-label phase 3 trial of BMS-936558 versus Investigator's Choice in advanced (Unresectable or Metastatic) Melanoma patients progressing post anti-CTLA-4 therapy." Total funding will be $163,096.
Michelle Winn of Nephrology has received an award from Genzyme Corporation for a project entitled "A Phase II, Multicenter, Double-Blind, Parallel Dosing, Randomized Study of Fresolimumab or Placebo in Patients with Steriod-Resistent Primary FSGS." Total funding will be $50,844.
Lesley H. Curtis of Other Medicine has received an award from GE Healthcare for a project entitled "Utilization of periphrocedural Imaging Surrounding Catheter Ablation of Atrial Fibrillation in Clinical Practice." Total funding will be $123,880.
Shelby Reed of Other Medicine has received an award from Cubist Pharmaceuticals, Inc. for a project entitled "Cubist Pharmaceuticals Economic Evaluation." Total funding will be $465,488.
Lake D. Morrison of Pulmonary, Allergy, and Critical Care Medicine has received an award from Boehringer Ingelheim Pharmaceuticals, Inc. for a project entitled "1199.33 BIBF 1120." Total funding will be $206,851.
Scott M. Palmer of Pulmonary, Allergy, and Critical Care Medicine has received an award from Boehringer Ingelheim Corporation for a project entitled "Prospective Multicenter U. S. Registry for Idiopathic Pulmonary Fibrosis." Total funding will be $3,453,937.
Scott M. Palmer of Pulmonary, Allergy, and Critical Care Medicine has received an award from Bristol-Myers Company for a project entitled "Phase 2 Study of the Safety and Efficacy in Subjects with Idiopathic Pulmonary Fibrosis." Total funding will be $9,330,619.[/tab]
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