Department of Medicine faculty have received notice of the following research, clinical trials, CME or other training awards.
[tabs style="vertical"][tab title="Sponsored research"]Gary M. Felker of Cardiology has received an award (UO1HL084904) from the National Institutes of Health for a project entitled "Oral Iron Repletion effects on Oxygen Uptake in Heart Failure."
Gary M. Felker of Cardiology has received an award (5R01-HL105448-03) from the National Institutes of Health for a project entitled "GUIDing Evidence Based Therapy Using Biomarker Intensified Treatment (CCC)." Total funding will be $5,481,050.
Neil J. Freedman of Cardiology has received an award (1R01-HL121689-01A1) from the National Institutes of Health for a project entitled “Anti-atherogenic Mechanisms of the Dual Rho-GEF Kalirin." Total funding will be $1,886,620.
Christopher Kontos of Cardiology has received an award (5T32-GM007171-40S1) from the National Institutes of Health for a project entitled "Medical Scientist Training Program." Total funding will be $100,268.
William E. Kraus of Cardiology has received an award from the Health Effects Institute for a project entitled "Air Quality by Genomics Interactions in a Cardiovascular Disease Cohort." Total funding will be $1,215,843.
Robert J. Lefkowitz of Cardiology has received an award from the American Society of Hematology for a project entitled "B-arrestin2 and the disease course of chronic myeloid leukemia (CML)." Total funding will be $55,000.
Sudarshan Rajagopal of Cardiology has received an award from the Burroughs Wellcome Fund for a project entitled "Dissecting Receptor Signaling Pathways in Pulmonary Hypertension." Total funding will be $700,000.
Anna Mae Diehl of Gastroenterology has received an award (2U01-DK061713-13) from the National Institutes of Health for a project entitled "NASH Clinical Research Network." Total funding will be $2,650,564.
Hayden B. Bosworth of General Internal Medicine has received an award from the PhRMA Foundation for a project entitled "Evaluating CVD Medication Adherence Program in Low SES." Total funding will be $149,478.
Leigh Boulware of General Internal Medicine has received an award (5R01-DK098759-02) from the National Institutes of Health for a project entitled "Transplant Social Worker Support for Live Kidney Donation in African Americans." Total funding will be $1,096,384.
Matthew L. Maciejewski of General Internal Medicine has received an award (1R01-HS023085-01) from the National Institutes of Health for a project entitled "Fragmentation of Medication Management in Medicare." Total funding will be $377,304.
Nirmish R. Shah of Hematology has received an award from the All Children's Hospital for a project entitled "Kids-DOTT." Total funding will be $3,697.
Mehri McKellar of Infectious Diseases has received an award from the NC Dept of Health and Human Services for a project entitled "Housing Opportunities for Persons with AIDS." Total funding will be $120,690.
Amy P. Abernethy of Medical Oncology has received an award from the American Institutes for Research for a project entitled "Clinical Data Transfer Agreement." Total funding will be $8,001.
Herbert I. Hurwitz of Medical Oncology has received an award (1 UM1-CA186704-01) from the National Institutes of Health for a project entitled "Subcontracts." Total funding will be $356,171.
Mary H. Foster of Nephrology has received an award (1R21-ES024451-01) from the National Institutes of Health for a project entitled "Mechanism of Silica-induced Autoimmunity." Total funding will be $235,750.
Lesley H. Curtis of Other Medicine has received a sub-award (N01-HC-25195) through Boston University for a project entitled "Framingham Study - Amendment 3." Total funding will be $20,648.
Lesley H. Curtis of Other Medicine has received a sub-award (HHSF223200910006I) through Harvard Pilgrim Health Care, Inc. for a project entitled "Blood-SCAN Feasibility Evaluation, Phase 3." Total funding will be $43,482.
Shelby Reed of Other Medicine has received a sub-award (1R01-AG04551-01A1) through Wake Forest University Health Sciences for a project entitled "REHAB HF." Total funding will be $37,462.
David M. Murdoch of Pulmonary, Allergy, and Critical Care Medicine has received an award (1R56-AI112360-01) from the National Institutes of Health for a project entitled "Magnetically directed single cell transcriptome analysis in HIV latency." Total funding will be $642,658.
Scott M. Palmer of Pulmonary, Allergy, and Critical Care Medicine has received an award (1U01-AI113315-01) from the National Institutes of Health for a project entitled "The Lung Transplant Clinical Trials Network (LT-CTN)." Total funding will be $12,938,896.
John S. Sundy of Pulmonary, Allergy, and Critical Care Medicine has received an award through the University of North Texas Health Science Center at Fort Worth for a project entitled "Primary Care Work Force Training - UNTHSC." Total funding will be $490,427.
Megan E. Clowse of Rheumatology and Immunology has received a sub-award (5U54-AR057319-11) through the University of Pennsylvania for a project entitled "University of Pennsylvania to Duke Subaward for RDCRC U54." Total funding will be $17,534.
Virginia B. Kraus of Rheumatology and Immunology has received an award from the National University of Singapore for a project entitled "A Randomized Controlled Trial of Colchicine for Symptom and Inflammation Modification in Knee Osteoarthritis." Total funding will be $110,231.
E. William St Clair of Rheumatology and Immunology has received a sub-award (UM1-AI09565-) through the Benaroya Research Institute at Virginia Mason for a project entitled "Subaward Agreement - Benaroya to Duke - Immune Tolerance Network." Total funding will be $128,011.[/tab][tab title="Industry-sponsored clinical trials"]John H. Alexander of Cardiology has received an award from Oxygen Biotherapeutics, Inc. for a project entitled "Levosimendan." Total funding will be $14,839,670.
Brett D. Atwater of Cardiology has received an award from St. Jude Medical Inc. for a project entitled "A safety and effectiveness trial for a leadless pacemaker system - The LEADLESS II Study." Total funding will be $113,868.
Robert M. Califf of Cardiology has received an award from Bayer Pharmaceuticals for a project entitled "Cardiovascular Drug Development." Total funding will be $15,000.
Robert M. Califf of Cardiology has received an award from Janssen Pharmaceutica, Inc. for a project entitled "Cardiovascular Drug Development." Total funding will be $20,000.
Christopher Granger of Cardiology has received an award from The Medicines Company for a project entitled "Regional Systems of Care Education: STEMI Systems Accelerator." Total funding will be $959,559.
John K. Harrison of Cardiology has received an award from Medtronic, Inc. for a project entitled "CoreValve Patient Education Pilot."
Adrian F. Hernandez of Cardiology has received an award from Amgen, Inc. for a project entitled "Optimize HF CMS." Total funding will be $128,276.
David F. Kong of Cardiology has received an award from Cardiovascular Systems Inc. for a project entitled "CSI Japan Coronary Clinical Research." Total funding will be $1,078,146.
William E. Kraus of Cardiology has received an award from Valencell, Inc for a project entitled "New Industry-funded Valencell Substudy." Total funding will be $7,670.
Mitchell W. Krucoff of Cardiology has received an award from Bayer Healthcare Pharmaceuticals Inc for a project entitled "Cardiac Safety Research Consortium." Total funding will be $75,000.
Chetan B. Patel of Cardiology has received an award from the Novartis Pharmaceuticals Corporation for a project entitled "A multicenter, randomized, double-blind, placebo-controlled phase IIIb study to evaluate the efficacy, safety and tolerability of Serelaxin when added to standard therapy in acute heart failure patients." Total funding will be $248,209.
Eric D. Peterson of Cardiology has received an award from the American College of Cardiology Foundation for a project entitled "TVT Registry Analytic Center Amendment 1." Total funding will be $819,775.
Thomas J. Povsic of Cardiology has received an award from Capricor Therapeutics, Inc. for a project entitled "Randomized, Double-Blind, Placebo-Controlled Phase I/II Study of the Safety and Efficacy of Intracoronary Delivery of Allogeneic Cardiosphere-Derived Cells in Patients With an Anterior Myocardial Infarction and Ischemic Left Ventricular Dysfunction ." Total funding will be $475,273.
Matthew T. Roe of Cardiology has received an award from Amgen, Inc. for a project entitled "Heart Failure: DCRI Learn Preceptorship." Total funding will be $42,320.
Tracy Y. Wang of Cardiology has received an award from the Boston Scientific Corporation for a project entitled "Assessment of ICD Candidacy among Older Patients after Acute Myocardial Infarction." Total funding will be $49,999.
Anna Mae Diehl of Gastroenterology has received an award from Shire Human Genetics Therapies for a project entitled "Evaluation of the ASBT inhibitor, SC-435, in a Mouse Model of Diet-induced Nonalcoholic Steatohepatitis (NASH)." Total funding will be $127,881.
Andrew J. Muir of Gastroenterology has received an award from Gilead Sciences, Inc. for a project entitled "GS-US-342-1137." Total funding will be $90,572.
Andrew J. Muir of Gastroenterology has received an award from Evidera for a project entitled "Evidera PSC." Total funding will be $25,320.
Keyur Patel of Gastroenterology has received an award from Hologic, Inc. for a project entitled "Aptima HCV." Total funding will be $47,601.
Keyur Patel of Gastroenterology has received an award from Gilead Sciences, Inc. for a project entitled "GS_US_342-1140." Total funding will be $81,609.
Dorothy Sipkins of Hematological Malignancies and Cellular Therapy has received an award from Gilead Sciences, Inc. for a project entitled "Investigation of PI3Kdelta inhibitor activity in mouse xenograft models of pre-B acute lymphoblastic leukemia ALL." Total funding will be $60,976.
Keith M. Sullivan of Hematological Malignancies and Cellular Therapy has received an award from AstraZeneca Pharmaceuticals, LP for a project entitled "13th Annual Fellows Research Retreat." Total funding will be $10,000.
Ara D. Metjian of Hematology has received an award from Omeros for a project entitled "A Phase 2, Uncontrolled, Two-stage, Dose-escalations Cohort Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, Immunogenicity, and Clinical activity of OMS721 in Adults with Thrombotic Microangiopathies." Total funding will be $113,403.
Thomas L. Ortel of Hematology has received an award from Alexion Pharmaceuticals, Inc. for a project entitled "ALXN1007-APS-201 An Open-label proof of concept Phase IIa trial of ALXN1007 for the treatment of non-criteria manifestations of Antiphospholipid Syndrome." Total funding will be $89,436.
Edward F. Hendershot of Infectious Diseases has received an award from Rempex Pharmaceuticals for a project entitled "Rempex 506-NH - Retro Chart Review." Total funding will be $14,840.
Mehri McKellar of Infectious Diseases has received an award from Bristol-Myers Squibb for a project entitled "BMS Study AI438-011, A Phase IIb Randomized, Controlled, Partially-Blinded Trial to Investigate Safety, Efficacy and Dose-response of BMS-663068 in Treatment-experienced HIV-1 Subjects, Followed by an Open-label Period on the Recommended Dose." Total funding will be $121,214.
Cameron R. Wolfe of Infectious Diseases has received a sub-award (HHSN261200800001E) through Social & Scientific Systems, Inc. for a project entitled "Task Order CRB-SSS-S-13-003314 - Protocol IRC 003." Total funding will be $105,668.
Cameron R. Wolfe of Infectious Diseases has received an award from Gilead Sciences, Inc. for a project entitled "Hematopoietic Cell Transplant (HCT)." Total funding will be $2,278,879.
Cameron R. Wolfe of Infectious Diseases has received an award from Gilead Sciences, Inc. for a project entitled "Hematopoietic Cell Transplant (HCT) (RSV) Infection of the Lower Respiratory Tract." Total funding will be $1,115,246.
Andrew Armstrong of Medical Oncology has received an award from the Bayer Corporation for a project entitled "Pharmacodynamic Study of Radium-223 in Men with Bone Metastatic Castration-Resistant Prostate Cancer (CRPC)." Total funding will be $927,447.
Frank R. Dunphy II of Medical Oncology has received an award from AstraZeneca AB for a project entitled "A lead-in phase II multicentre, randomised, double-blind study comparing AZD1775 plus Docetaxel and placebo plus Docetaxel in previously treated non-small-cell-lung cancer patients." Total funding will be $146,896.
Herbert I. Hurwitz of Medical Oncology has received an award from F. Hoffmann-La Roche Ltd for a project entitled "A phase II multicenter randomized double blinded study to evaluate the efficacy and asfety of R05520985 plus FOLFOX versus Bevacizumab plus FOLFOX in patients with previously untreated metastatic colorectal cancer." Total funding will be $712,360.
Herbert I. Hurwitz of Medical Oncology has received an award from MedPacto, Inc for a project entitled "First-in-human dose escalation of TEW-7197 monotherapy in subjects with advanced stage solid tumors." Total funding will be $1,832,840.
Herbert I. Hurwitz of Medical Oncology has received an award from Novartis Pharmaceuticals Corporation for a project entitled "Modular Phase II study of linked targeted therapy to patients with patheway activated tumors." Total funding will be $97,283.
Neal E. Ready of Medical Oncology has received an award from Janssen Research & Development, LLC for a project entitled "A Phase I study to evaluate the saftey, phamocokinetics and pharmacodynamics of JNJ-42756493 a pan-fibroblat growth factor receptor." Total funding will be $300,174.
Timothy J. McMahon of Pulmonary, Allergy, and Critical Care Medicine has received an award from Aries Pharmaceuticals for a project entitled " A PHASE 2, MULTI-CENTER, OPEN-LABEL, RANDOMIZED, PARALLEL-DOSE STUDY TO DETERMINE THE SAFETY AND EFFICACY OF AIR001 IN SUBJECTS WITH WHO GROUP 1 PULMONARY ARTERIAL HYPERTENSION." Total funding will be $124,037.
Lake D. Morrison of Pulmonary, Allergy, and Critical Care Medicine has received an award from Boehringer Ingelheim Pharmaceuticals, Inc. for a project entitled "Idiopathic Pulmonary Fibrosis Prespective Outcomes (IPF-PRO) Registry." Total funding will be $54,340.
Scott M. Palmer of Pulmonary, Allergy, and Critical Care Medicine has received an award from Gilead Sciences, Inc. for a project entitled "IPF/ILD_Biomarkers Pilot Study." Total funding will be $78,313.[/tab]
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