New funding awards - March 2019

Sponsored Research

William Herzog of Cardiology has received a sub-award (5UH3-AT009149-04) through the Mount Sinai Medical Center for a project entitled "TACT2." Total funding will be $3,000.

William Jones of Cardiology has received a sub-award (1252) through the Vanderbilt University Medical Center for a project entitled "MSCDRN application." Total funding will be $182,181.

Yongmei Liu of Cardiology has received a sub-award (1R01-ES028758-01A1 REVIS) through the Columbia University for a project entitled "Low-level Arsenic Exposure and Cardiovascular Disease in Multi-Ethnic Adults." Total funding will be $27,678.

Sudha Shenoy of Cardiology has received an award (1R01-HL142286-01A1) from the National Institutes of Health for a project entitled "Regulation of Vascular Inflammatory Signaling by the Deubiquitinase USP20." Total funding will be $2,137,397.

Kathleen Cooney of Chair's Office has received an award (W81XWH-16-1-0713-PC151032) from the Department of Defense for a project entitled "Characterizing the Genetic Landscape of Prostate Cancer in Young African American Men - HDRA." Total funding will be $526,061.

Jatin Roper of Gastroenterology has received an award (7K08-CA198002-04) from the National Institutes of Health for a project entitled "The role of Mtss1 in Hedgehog-mediated intestinal cancer stem cell function." Total funding will be $302,395.

Kenneth Lyles of Geriatrics has received a sub-award (1R01-AG059417-01A1) through the California Pacific Medical Center for a project entitled "Prevention of Fractures in Patients with Parkinson's Disease." Total funding will be $73,315.

Nelson Chao of Hematologic Malignancies and Cellular Therapy has received an award (1UG3-TR002448-01) from the National Institutes of Health for a project entitled "AZD9668 and Neutrophil Elastase Inhibition to Prevent Graft-versus-Host Disease." Total funding will be $474,721.

Nelson Chao of Hematologic Malignancies and Cellular Therapy has received a sub-award () through the National Marrow Donor Program for a project entitled "RITN 2019." Total funding will be $8,000.

Nirmish Shah of Hematology has received a sub-award (1R01-AT010413-01) through the Northwestern University for a project entitled "SCH: INT: Collaborative Research: Development and analysis of integrative models for chronic pain." Total funding will be $82,500.

Susanna Naggie of Infectious Diseases has received a sub-award (7UM-AI068636-13) through the University of California - Los Angeles for a project entitled "Leadership and Operations Center (LOC), Aids Clinical Trial Group (ACTG) HEP Committee Chair." Total funding will be $9,462.

Jeffrey Crawford of Medical Oncology has received an award (1UG1-CA233253-01) from the National Institutes of Health for a project entitled "NCI National Clinical Trials Network (UG1)." Total funding will be $2,710,908.

Kelly Marcom of Medical Oncology has received a sub-award () through the Mayo Clinic for a project entitled "TBCRC 041 Randomized Phase II Trial to Evaluate Alisertib Alone or Combined with Fulvestrant in Women with Advanced, Hormone-Receptor Positive (HR+) Breast Cancer." Total funding will be $83,485.

Kelly Westbrook of Medical Oncology has received a sub-award () through the Johns Hopkins University for a project entitled "TBCRC45: AVIATOR: A Phase II Study Of Trastuzumab, Vinorelbine, and Avelumab ± PF-05082566 (4-1BB/CD137 Agonist) in HER2+ MBC." Total funding will be $72,000.

Christina Wyatt of Nephrology has received a sub-award (5P01-DK056492-18) through the Baylor College of Medicine for a project entitled "Longterm Consequences of HIV in the Kidney: Core C." Total funding will be $149,784.

Christopher Cox of Pulmonary has received an award (1R01-AG058915-01A1) from the National Institutes of Health for a project entitled "PCplanner: operationalizing needs-focused palliative care for older adults in intensive." Total funding will be $2,744,202.

Industry-sponsored Clinical Trials

Kevin Jackson of Cardiology has received an award from SentreHEART, Inc for a project entitled "Left Atrial Appendage Ligation with the Lariate Suture Delivery System as Adjunctive Therapy to Pulmonary Vein Isolation for Persistent or Lonagstanding Persistent Atrial Fibrillation." Total funding will be $103,722.

Mitchell Krucoff of Cardiology has received an award from W. L. Gore & Associates, Inc. for a project entitled "MDEpinNet: RAPID Phase II." Total funding will be $9,999.

Jonathan Piccini of Cardiology has received an award from Medtronic, Inc. for a project entitled "Micra Atrial Tracking Using A Ventricular Accelerometer 2." Total funding will be $41,289.

Jonathan Piccini of Cardiology has received an award from Medtronic, Inc. for a project entitled "HRQoL Project." Total funding will be $2,500.

Svati Shah of Cardiology has received an award from AstraZeneca AB for a project entitled "ASTRAZENECA AB." Total funding will be $1,500,000.

Hiba Abouassi of Endocrinology has received an award from Novo Nordisk, Inc. for a project entitled "Semaglutide effects on cardiovascular outcomes in people with overweight or obesity." Total funding will be $678,286.

Mark Herman of Endocrinology has received an award from Eli Lilly and Company for a project entitled "The Role of HGFAC in Metabolic Disease." Total funding will be $300,000.

Hans-Ewald Hohmeier of Endocrinology has received an award from Eli Lilly and Company for a project entitled "Small molecules with pleiotropic positive effects on beta-cell health." Total funding will be $300,000.

Deborah Muoio of Endocrinology has received an award from Eli Lilly and Company for a project entitled "Role of cardiac and skeletal muscle ketone oxidation in permitting adaptive mitochondrial remodeling in response to lipid stress." Total funding will be $300,000.

Jane Onken of Gastroenterology has received an award from Boehringer Ingelheim Corporation for a project entitled "Boehringer Ingelheim Pharmaceuticals Inc - Industry - BI 655130 in Ulcerative Colitis Subjects." Total funding will be $132,430.

Harry Erba of Hematologic Malignancies and Cellular Therapy has received an award from Daiichi Sankyo Inc for a project entitled "A PHASE 1 STUDY OF DS-3032B IN COMBINATION WITH QUIZARTINIB IN SUBJECTS WITH FLT3-ITD MUTANT ACUTE MYELOID LEUKEMIA THAT ARE RELAPSED/REFRACTORY, OR NEWLY DIAGNOSED AND UNFIT FOR INTENSIVE CHEMOTHERAPY." Total funding will be $289,790.

Marilyn Telen of Hematology has received an award from FORMA Therapeutics, Inc. for a project entitled "FORMA Therapeutics FT-4202." Total funding will be $253,039.

Barbara Alexander of Infectious Diseases has received an award from Cidara Therapeutics, Inc. for a project entitled "ReSTORE - A phase 3 study of the efficacy and safety of rezafungin for injection versus intravenous caspofungin followed by optional oral fluconazole step-down in the treatment of subjects with candidemia and/or invasive candidiasis." Total funding will be $155,869.

Daniel George of Medical Oncology has received an award from Calithera Biosciences, Inc. for a project entitled "A Randomized, Double-Blind, Placebo-Controlled Phase 2 Study Comparing CB-839 in Combination with Cabozantinib (CB-Cabo) vs. Placebo with Cabozantinib (Pbo-Cabo) in Patients with Advanced or Metastatic Renal Cell Carcinoma (RCC)." Total funding will be $127,642.

Niharika Mettu of Medical Oncology has received an award from Bristol-Myers Squibb Company for a project entitled "A Randomized, Open-Label, Phase 2 Study of Nivolumab in Combination with Ipilimumab or Nivolumab Monotherapy in Participants with Advanced or Metastatic Solid Tumors of High Tumor Mutational Burden (TMB-H)." Total funding will be $141,274.

Andrew Nixon of Medical Oncology has received an award from HTG Molecular Diagnostics, Inc for a project entitled "Pilot Study for Feasibility of Next Generation Sequencing for Detection of Lung Cancer ALK and ROS1 Mutation.." Total funding will be $3,999.

Tian Zhang of Medical Oncology has received an award from Bristol-Myers Squibb Company for a project entitled "A Phase 2, Fast Real-time Assessment of Combination Therapies in Immuno-ONcology Study in Participants with Advanced Renal Cell Carcinoma (FRACTION-RCC)." Total funding will be $10,200.

John Middleton of Nephrology has received an award from Relypsa, Inc. for a project entitled "Patiromer Efficacy to Reduce Episodic Hyperkalemia in End Stage Renal Disease Patients Treated with Hemodialysis (PEARL-HD)." Total funding will be $400,443.

Kamran Mahmood of Pulmonary has received an award from Olympus Corporation for a project entitled "Current Trends in Pleural Disease Management -- 2019." Total funding will be $4,000.

Timothy Scialla of Pulmonary has received an award from Sanofi US for a project entitled "A randomized, double-blind, placebo-controlled, parallel-group, Proof-of-Concept (PoC) study to assess the efficacy, safety and tolerability of SAR440340, in patients with moderate-to-severe chronic obstructive pulmonary disease (COPD)." Total funding will be $142,315.

Lisa Criscione-Schreiber of Rheumatology has received an award from Pfizer, Inc. for a project entitled "NP/PA Fellowship." Total funding will be $157,000.

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