Department of Medicine faculty have received notice of the following research, clinical trials, CME or other training awards.
Sponsored research
Chetan B. Patel of Cardiology has received a sub-award (CDR-1310-06998) through the University of Colorado - Denver for a project entitled "A multicenter trial of a novel decision aid for patients and their caregivers offered destination therapy left ventricular assist device." Total funding will be $73,238.
Sudarshan Rajagopal of Cardiology has received an award through the University of California - San Diego for a project entitled "US CTEPH Registry." Total funding will be $87,550.
Sudha Shenoy of Cardiology has received an award from the American Heart Association for a project entitled "De-ubiquitination of beta adrenergic receptors and left ventricular hypertrophy." Total funding will be $77,000.
Ashley Williams (Mentor: Deborah Muoio) of Endocrinology, Metabolism, and Nutrition has received an award (1F32-DK105922-01) from the National Institutes of Health for a project entitled "Mitochondrial Protein Acetylation and Energy Metabolism in Muscle." Total funding will be $157,290.
Ebony Boulware of General Internal Medicine has received a sub-award (HHSN268201300047C) through the University of Mississippi Medical Center for a project entitled "Jackson Heart Study Kidney Disease Working Group." Total funding will be $22,248.
Cristina Gasparetto of Hematological Malignancies and Cellular Therapy has received an award from the National Marrow Donor Program for a project entitled "Multicenter Phase II, Double-blind Placebo Controlled Trial of Maintenance Ixazomib BMT CTN 1302."
Vivian H. Chu of Infectious Diseases has received an award (HHSN272200900023C) from the National Institutes of Health for a project entitled "A Phase lll Multi-Center, Randomized, Open-label, Comparative Study to Assess the Efficacy of a Treatment Algorithm to Reduce the Use of Vancomycin in Patients with Intravenous Catheter-Associated Bloodstream Infections (BSI) due to Staphylococci."
Mehri McKellar of Infectious Diseases has received a sub-award (R24-AG044325-) through Wake Forest University Health Sciences for a project entitled "Developing a Testable Psychoeducation Program for Informal Caregivers of Persons Living with HIV/AIDS and Associated Neurocognitive Disorders." Total funding will be $5,000.
Susanna Naggie of Infectious Diseases has received a sub-award (1U01-HL123336-) through Massachusetts General Hospital for a project entitled "Randomized Trial to Prevent Vascular Events in HIV- REPRIEVE (A5332)."
Melissa E. Hector-Greene (Mentor: Gerard C. Blobe) of Medical Oncology has received an award (1F31-CA196239-01) from the National Institutes of Health for a project entitled "The Role of Type III TGF-beta Receptor in ALK1-mediated Tumor Angiogenesis." Total funding will be $67,654.
Shiaowen D. Hsu of Medical Oncology has received an award (1R21-CA185807-01A1) from the National Institutes of Health for a project entitled "Targeting Calreticulin in Colorectal Cancer Liver Metastasis." Total funding will be $380,045.
Thomas M. Coffman of Nephrology has received an award (1R01-DK105049-01) from the National Institutes of Health for a project entitled "Paracrine Control of Blood Pressure by Renal Intercalated Cells." Total funding will be $1,788,000.
Stacy A. Johnson (Mentor: Susan B. Gurley) of Nephrology has received an award from the ASN Foundation for Kidney Research for a project entitled "The Role of Branched-chain Amino Acids in Diabetic Nephropathy." Total funding will be $100,000.
Lesley H. Curtis of Other Medicine has received a sub-award (HHSN268201300036C) through the University of Washington for a project entitled "CHS." Total funding will be $19,911.
Claude A. Piantadosi of Pulmonary, Allergy, and Critical Care Medicine has received an award (N00014-15-1-2072) from the Office of Naval Research for a project entitled "Critical Molecular Targets for the Toxic Effects of Hyperbaric Oxygen and a Novel Pharmacological Approach for Preventing Acute Toxicity." Total funding will be $1,094,199.
Megan E. Clowse of Rheumatology and Immunology has received a sub-award (2U54-AR057319-12) through the University of Pennsylvania for a project entitled "University of Pennsylvania to Duke Subaward for U54 Grant." Total funding will be $8,898.
Industry-sponsored clinical trials
Camille G. Frazier-Mills of Cardiology has received an award from Medtronic, Inc. for a project entitled "Wrap-it." Total funding will be $40,424.
Thomas J. Povsic of Cardiology has received an award from Cardio3 Biosciences for a project entitled "CHART2." Total funding will be $425,992.
Eric Velazquez of Cardiology has received an award from Alnylam Pharmaceuticals for a project entitled "A Study Examining the Prevalence of TTR Mutations in Subjects Suspected of Having Cardiac Amyloidosis." Total funding will be $48,552.
Tracy Y. Wang of Cardiology has received an award from Boston Scientific Corporation for a project entitled "Evaluation of Reasons for ICDs not being Implanted after MI." Total funding will be $58,557.
Andrew J. Muir of Gastroenterology has received an award from Merck Sharp & Dohme for a project entitled "Merck MK-5172-017-02 A long-term follow-up study to evaluate the durability of Viro-Logic response and/or viral resistance patterns of subjects with Chronic Hepatitis C who have been previously treated with MK-5172 in a prior clinical trial." Total funding will be $78,182.
Rowena J. Dolor of General Internal Medicine has received an award from Janssen Research & Development, LLC for a project entitled "CaRE Trial." Total funding will be $213,844.
Connie Bales of Geriatrics has received an award from Dairy Management, Inc. for a project entitled "An Enhanced Protein (Dairy) Weight Loss Intervention for Dynapenic Obesity: Impact on Muscle Quality and Composition." Total funding will be $497,772.
Gwynn D. Long of Hematological Malignancies and Cellular Therapy has received an award from Novartis Pharmaceuticals Corporation for a project entitled "A multi-center study to evaulate the efficacy and safety of CSJ148." Total funding will be $136,197.
David Rizzieri of Hematological Malignancies and Cellular Therapy has received an award from Karyopharm Therapeutics for a project entitled "Phase II study of SINE (KPT-330) vs SOC in patients with R/R AML." Total funding will be $94,887.
Jeffrey Crawford of Medical Oncology has received an award from Celgene Corporation for a project entitled "CELGENE SOLID TUMOR PRACTICUM." Total funding will be $77,280.
Stephanie Gaillard of Medical Oncology has received an award from the Bristol-Myers Squibb Company for a project entitled "A phase I/IIa study of BMS986148 a Mesothelin directed antibody drug conjugate in subjects with select advanced solid tumors." Total funding will be $587,171.
Michael R. Harrison of Medical Oncology has received an award from Acerta Pharma for a project entitled "Randomized Phase 2 Trial of ACP-196 and Pembrolizumab Immunotherapy Dual Checkpoint Inhibition in Platinum Resistant Metastatic Urothelial Carcinoma." Total funding will be $413,562.
Neal E. Ready of Medical Oncology has received an award from AstraZeneca Pharmaceuticals, LP for a project entitled "A phase II, multi-center, single-arm, global study of MEDI4736 monotherapy in patients with recurrent or metastatic squamous cell carcinoma of the head and neck (SCCHN)." Total funding will be $273,897.
April K. Salama of Medical Oncology has received an award from Bristol-Myers/Sanofi Pharmaceuticals, Inc. Partnership for a project entitled "BMS CA209-238-0025 A Phase 3, Randomized, Double-blind Study of Adjuvant Immunotherapy with Nivolumab versus Ipilimumab after Complete Resection of Stage IIIb/c or Stage IV Melanoma in Subjects who are at high risk for recurrence." Total funding will be $282,011.
John P. Middleton of Nephrology has received an award from Janssen Research & Development, LLC for a project entitled "Protocol No. 28431754DNE3001: "A Randomized, Double-blind, Event-driven, Placebo-controlled, Multicenter Study of the Effects of Canagliflozin on Renal and Cardiovascular Outcomes in Subjects With Type 2 Diabetes Mellitus and Diabetic Nephropathy." Total funding will be $503,419.
Neil R. MacIntyre of Pulmonary, Allergy, and Critical Care Medicine has received an award from GlaxoSmithKline for a project entitled "GSK Study CTT116855." Total funding will be $345,748.
Momen Wahidi of Pulmonary, Allergy, and Critical Care Medicine has received an award from Mercator MedSystems, Inc. for a project entitled "BROADWAY: Broncho-Adventitial Delivery of Paclitaxel to Extend Airway Patency in Malignant Airway Obstruction Patients." Total funding will be $5,100.