New funding awards - November 2013

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Department of Medicine faculty have received notice of the following research, clinical trials, CME or other training awards. [tabs style="vertical"][tab title="Sponsored research"]Christopher Kontos of Cardiology has received a sub-award (3R01-AR060701-04S1) through the University of Kentucky for a project entitled "The role of satellite cells in adult skeletal muscle growth and maintenance." Total funding will be $55,699. Jonathan P. Piccini of Cardiology has received an award from the ResMed Foundation for a project entitled "CAT-HF: Biomarkers Costs." Total funding will be $145,537. Wei Chen of Gastroenterology has received an award (1R01-CA172570-01A1) from the National Institutes of Health for a project entitled "Inhibition of Wnt/B-Catenin Signaling in Colorectal Cancer Therapy." Total funding will be $1,628,875. Rodger A. Liddle of Gastroenterology has received an award (1R01-DK098796-01A1) from the National Institutes of Health for a project entitled "Receptor Regulation of CCK Cell Function." Total funding will be $1,365,900. Danielle M. Brander of Hematological Malignancies and Cellular Therapy has received an award from the Lymphoma Research Foundation of America for a project entitled "A Phase I Trial of a Bcl-2 inhibitor and a MEK inhibitor for patients with relapsed indolent B-NHL." Total funding will be $10,000. Keith M. Sullivan of Hematological Malignancies and Cellular Therapy has received an award (HHSN272201100025C) from the National Institutes of Health for a project entitled "Scleroderma Cyclophosphamide or Transplantation (SCOT) Trial-Option 3." Total funding will be $734,832. Gowthami Arepally of Hematology has received a sub-award (1U19-FD004994-01) through the University of North Carolina - Chapel Hill for a project entitled "Probing the heparin structural elements for high risk of heparin-induced thrombocytopenia (HIT)." Total funding will be $34,540. Nathan M. Thielman of Infectious Diseases has received a sub-award (5R25-TW0093-02) through Vanderbilt University for a project entitled "Vanderbilt-Emory-Cornell-Duke Consortium for Global Health Fellows (VECDor)." Total funding will be $48,700. Amy P. Abernethy of Medical Oncology has received a sub-award (HHSH250201200016C) through the Medical College of Wisconsin for a project entitled "Stem Cell Therapeutic Outcomes Database." Total funding will be $17,548. Andrew Armstrong of Medical Oncology has received an award through the Weill Medical College of Cornell University for a project entitled "A Phase 2 Trial of the Aurora Kinase A Inhibitor MLN8237 in Patients with Metastatic Castrate Resistant and Neuroendocrine Prostate Cancer." Total funding will be $84,268. Jeffrey Peppercorn of Medical Oncology has received an award from the Greenwall Foundation for a project entitled "Does Comparative Effectiveness Research Promote Rationing or Rational Cancer Care?" Total funding will be $46,780. Ivan Spasojevic of Medical Oncology has received an award from the Duke Coulter Translational Partnership for a project entitled "Preclinical development and proof of concept of a new antioxidant for therapeutic, MnTBuOE-2-PyP5+." Total funding will be $26,080. Syed Y. Zafar of Medical Oncology has received an award from Brigham and Women's Hospital for a project entitled "Financial Assistance, Navigation, and Communication Education (FinANCE): Development and pilot testing of a web-based financial toxicity intervention." Total funding will be $157,000. John P. Middleton of Nephrology has received a sub-award (1U01-DK099877-01) through the Cleveland Clinic Lerner College of Medicine for a project entitled "Data Coordinating Center for Pilot Studies of Candidate Therapies for CKD." Total funding will be $12,098. Claude A. Piantadosi of Pulmonary, Allergy, and Critical Care Medicine has received an award (N00014-11-1-0040) from the Office of Naval Research for a project entitled "Afferent Autonomic Pathways in Hyperbaric Oxygen Toxicity: New Targets for Preventing Seizures and Lung Injury." Total funding will be $1,042,161.[/tab][tab title="Industry-sponsored clinical trials"]James P. Daubert of Cardiology has received an award from Biosense Webster Inc for a project entitled "reMARQable Training." Total funding will be $2,500. Igor Klem of Cardiology has received an award through Heart Imaging Technologies, LLC for a project entitled "Medical Images, HTML5, and Clinical Trial Remote Collaboration." Total funding will be $55,653. William E. Kraus of Cardiology has received an award from Gilead Sciences, Inc. for a project entitled "Effects of Ranolazine plus Exercise on Stable Angina and Daily Physical Activity." Total funding will be $457,402. Robert J. Noveck of Cardiology has received an award from Cardioxyl Pharmaceuticals for a project entitled "LOI - Safety of Continuous Infusion of CXL-XXX." Total funding will be $20,000. Robert J. Noveck of Cardiology has received an award from Acorda Therapeutics, Inc for a project entitled "A Double-Blind Pharacokinetic Interaction Study Evaluating the Effect of a Single IV Infusion of GGF2 or Placebo on Midazolam Pharmacokinetics in Patients with Heart Failure." Total funding will be $194,570. Manesh R. Patel of Cardiology has received an award from Cleveland Heart, Inc for a project entitled "Efficacy Evaluation of Coronary Analyzer KH-3000TM for Diagnosis of Coronary Artery Disease in Patients with Angina." Total funding will be $100,000. Jonathan P. Piccini of Cardiology has received an award from ARCA Biopharma Inc. for a project entitled "GENETIC-AF." Total funding will be $8,950,707. Matthew T. Roe of Cardiology has received an award from The FH Foundation for a project entitled "CASCADE Registry." Total funding will be $1,241,803. Pierluigi Tricoci of Cardiology has received an award from Amgen, Inc. for a project entitled "Amgen Psoriatic Arthritis Studies 0406." Total funding will be $299,965. Pierluigi Tricoci of Cardiology has received an award from Amgen, Inc. for a project entitled "Amgen Psoriatic Arthritis Study 0144." Total funding will be $193,458. Andrew J. Muir of Gastroenterology has received an award from Cook Endoscopy for a project entitled "Cook Endoscopy Fellowship Agreement." Total funding will be $60,000. Hans L. Tillmann of Gastroenterology has received an award from The Bristol-Myers/Sanofi Pharmaceuticals, Inc. Partnership for a project entitled "Pilot Study to Assess Changes in Immuneregulation with Phase of Chronic HBV Infection and Antiviral Therapy." Total funding will be $37,279. Susanna Naggie of Infectious Diseases has received an award from AbbVie Inc. for a project entitled "A Randomized Open-label Study to Evaluation the Safety and Efficacy of ABT-450." Total funding will be $627,203. Cameron R. Wolfe of Infectious Diseases has received an award from Ansun BioPharma,Inc for a project entitled "An Open Label study to examine the effects of DAS 181 administered by Dry Powder Inhaler (DPI) or Nebulized formulation in Immunocompromised subjects with Parainfluenza (PIV) Infection." Total funding will be $160,488. Cameron R. Wolfe of Infectious Diseases has received an award from Genentech, Inc. for a project entitled "Roche Tamiflu Protocol NV20234, A double-blind, randomized, stratified, multi-center trial evaluating conventional and high dose oseltamivir in the treatment of immunocompromised patients with influenza." Total funding will be $61,774. Amy P. Abernethy of Medical Oncology has received an award from Sanofi US for a project entitled "Think Tank on Data Needs and Infrastructure in Oncology Conference." Total funding will be $25,000. Amy P. Abernethy of Medical Oncology has received an award from Helsinn Therapeutics (U.S.), Inc. for a project entitled "Retrospective Data Analysis and Manuscript." Total funding will be $200,000. Jeffrey Crawford of Medical Oncology has received an award from GTx, Inc. for a project entitled "GTx Lead Principal Investigator Agreement." Total funding will be $69,655. Frank R. Dunphy II of Medical Oncology has received an award from Novartis Pharmaceuticals Corporation for a project entitled "A multicenter, open-label, randomized phase II study to evaluate the efficacy of AUY922 vs pemetrexed or docetaxel in NSCLC patients with EGFR mutations who have progressed on prior EGFR TKI treatment." Total funding will be $532,070. Daniel J. George of Medical Oncology has received an award from Exelixis, Inc for a project entitled "A Phase 3, Randomized, Controlled Study of Cabozantinib (XL184) vs Everolimus in Subjects with Metastatic Renal Cell Carcinoma that has Progressed after Prior VEGFR Tyrosine Kinase Inhibitor Therapy." Total funding will be $294,867. Daniel J. George of Medical Oncology has received an award from Medivation, Inc. for a project entitled "Medivation Prostate Disease Training Program-Pilot - Medivation Prostate Practicum." Total funding will be $65,240. Michael R. Harrison of Medical Oncology has received an award from Argos Therapeutics, Inc. for a project entitled "RNA Extraction and Amplification from Biopsy Specimens in Subjects with Metastatic Renal Cell Carcinoma." Total funding will be $103,598. Michael A. Morse of Medical Oncology has received an award from AlphaVax, Inc. for a project entitled "A pilot study of active immunotherapy with CEA (6D) VRP vaccine (AVX701) in patients with stage III colon cancer." Total funding will be $212,843. Andrew B. Nixon of Medical Oncology has received an award from Tracon Pharmaceuticals, Inc. for a project entitled "Analysis of samples from the phase I study, An Open Label Phase 1B Dose-Escalation Study of TRC105 Combined with Solid Tumors." Total funding will be $134,117. Neal E. Ready of Medical Oncology has received an award from Genentech, Inc. for a project entitled "A phase II, multicenter, single-arm study of MPDL3280A in patients with advanced PD-L1_positive Locally advanced or Metastatic non-small cell lung cancer." Total funding will be $4,986,946. Richard F. Riedel of Medical Oncology has received an award from Tracon Pharmaceuticals, Inc. for a project entitled "A Phase IB Dose-Escalation Study of TRC105 in combination with Pazopanib in Patients with Advanced Soft Tissue Sarcoma." Total funding will be $110,552. April K. Salama of Medical Oncology has received an award from Bristol-Myers Company for a project entitled "BMS IPLMUMAB." Total funding will be $216,381. John H. Strickler of Medical Oncology has received an award from AbbVie Inc. for a project entitled "A Multicenter phase 1/1b open label dose escalation study of ABT-165 a dual variable domain immunoglobin in subject with advanced solid tumors." Total funding will be $720,066. John P. Middleton of Nephrology has received an award from Bristol-Myers Squibb for a project entitled "BMS CV202-010-0055." Total funding will be $43,978. Njira L. Lugogo of Pulmonary, Allergy, and Critical Care Medicine has received an award from GlaxoSmithKline for a project entitled "MEA115661: A multi-centre, open-label, long-term safety study of mepolizumab in asthmatic subjects." Total funding will be $284,504. Scott M. Palmer of Pulmonary, Allergy, and Critical Care Medicine has received an award from Gilead Sciences, Inc. for a project entitled "AZLI in lung transplant recipients." Total funding will be $46,188.[/tab] [/tabs]

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