Congratulations to the following faculty members for receiving these sponsored research awards for November and December.
Sponsored Research
Ravi Karra of Cardiology has received an award from the The Foundation for Sarcoidosis Research for a project entitled "Repurposing 99mTc-tilmanocept Imaging for Cardiac Sarcoidosis." Total funding will be $100,000.
Manesh Patel of Cardiology has received a sub-award () through the Digital Medicine Society for a project entitled "Implementation of Fit-For-Purpose Al solutions in low-resource health systems (DiMe)." Total funding will be $199,954.
Senthil Selvaraj of Cardiology has received an award from the American Academy of CME Inc for a project entitled "ATTR Early-Career Research Forum." Total funding will be $100,000.
Ranee Chatterjee Montgomery of General Internal Medicine has received a sub-award (IHS-2020C1-19350-IC) through the Wake Forest University Health Sciences for a project entitled "Helping Patients Achieve Kidney Transplants through Health System Change." Total funding will be $1,951,968.
James Wharam of General Internal Medicine has received a sub-award () through the Harvard Pilgrim Health Care, Inc. for a project entitled "Reducing disparities in alcohol use disorder treatment in underserved areas." Total funding will be $41,567.
Cathleen Colon-Emeric of Geriatrics has received a sub-award (1U24-AG087939-01) through the The Trustees of Indiana University for a project entitled "The NH Explanatory Trials Network: Supporting Transformation by Enhancing Partnerships (The NEXT STEPS)." Total funding will be $31,325.
James White of Hematology has received an award from the National Academy of Medicine for a project entitled "Adoptive heterochronic T cell transfer to target senescence and health span." Total funding will be $50,000.
Joshua Parsons of Infectious Diseases has received an award (1K08-AI187747-01) from the National Institutes of Health for a project entitled "Genomic determinants of antibiotic treatment failure in S. aureus bacteremia." Total funding will be $942,688.
John Perfect of Infectious Diseases has received a sub-award (2U19-AI110818-11) through the Broad Institute for a project entitled "Advancing genomic, transcriptomic and functional approaches to combat globally important and emerging pathogens (U19)." Total funding will be $67,000.
John Perfect of Infectious Diseases has received a sub-award (R01-AI123315-) through the Rutgers, The State University of New Jersey for a project entitled "The Role of Inositol in Cryptococcus Biology and Pathogenesis." Total funding will be $40,339.
Industry Sponsored Clinical Trials
Marat Fudim of Cardiology has received an award from Endotronix, Inc. for a project entitled "A Prospective, Multi-Center, Open Label, Randomized Control Clinical Trial Evaluating the Safety and Efficacy of the Cordella Pulmonary Artery Sensor System in New York Heart Association (NYHA) Class II Heart Failure Patients (PROACTIVE-HF-2 Trial)." Total funding will be $1,310,106.
Marat Fudim of Cardiology has received an award from Sardocor Corp. for a project entitled "SRD-001-1001." Total funding will be $443,098.
Marat Fudim of Cardiology has received an award from Novo Nordisk A/S for a project entitled "Poseidon." Total funding will be $114,406.
Stephen Greene of Cardiology has received an award from AstraZeneca Pharmaceuticals, LP for a project entitled "AZAB - Baxdrostat DS - Industry." Total funding will be $65,660.
Jonathan Piccini of Cardiology has received an award from Bayer Aktiengesellschaft (same as Bayer AG) for a project entitled "Bayer AG - Bayer aFib DS - Industry." Total funding will be $76,475.
Sean Pokorney of Cardiology has received an award from Boston Scientific Corporation for a project entitled "ACL ADVANTAGE AF: A Prospective Single Arm Open Label Study of the FARAPULSE Pulsed Field Ablation System in Subjects with Persistent Atrial Fibrillation." Total funding will be $88,355.
Nishant Shah of Cardiology has received an award from Novartis Pharmaceuticals Corporation for a project entitled "V-INCLUSION." Total funding will be $637,135.
Cristina Gasparetto of Cell Therapy has received an award from CARSgen Therapeutics Corporation for a project entitled "A Phase 1, Multicenter, Open-Label Study of CB-011, a CRISPR-Edited Allogeneic Anti-BCMA CAR-T Cell Therapy in Patients with Relapsed/Refractory Multiple Myeloma (CaMMouflage Trial)." Total funding will be $15,830.
Amreen Dinani of Gastroenterology has received an award from 89bio, Inc for a project entitled "BIO89-100-132 The ENLIGHTEN-Cirrhosis Pro00116849." Total funding will be $418,066.
James Davis of General Internal Medicine has received a sub-award (1R42-DA060773-01) through Predictably Human, Inc for a project entitled "Assessment of a Digitally Controlled Aerosolized Nicotine Replacement Therapy." Total funding will be $219,989.
Jacqueline Hodges of Infectious Diseases has received an award from Gilead Sciences, Inc. for a project entitled "Gilead Sciences Research Scholars Program in HIV (PI TRANSFER)." Total funding will be $180,000.
Becky Smith of Infectious Diseases has received an award from RESTEC Solutions, LLC for a project entitled "Measuring the efficacy of the SONOPRO disinfection cabinet on inpatient clinician-assigned phones." Total funding will be $26,668.
Nicholas DeVito of Oncology has received an award from Agenus, Inc. for a project entitled "Botensilimab and Balstilimab Optimization in Colorectal Cancer (BBOpCo)." Total funding will be $1.
Juneko Grilley Olson of Oncology has received an award from Boehringer Ingelheim Pharmaceuticals, Inc. for a project entitled "Brightline-3: A Phase III, randomized, open-label, multi-center trial of brigimadlin + ezabenlimab compared to gemcitabine + docetaxel for second-line treatment of patients with advanced TP53 wild-type soft tissue sarcoma subtypes." Total funding will be $25,748.
Michael Harrison of Oncology has received an award from AbbVie Inc. for a project entitled "A Phase I/IIa theranostic study of 64Cu-SAR-BBN and 67CuSAR-BBN for identification and treatment of RPRexpressing metastatic castrate resistant prostate cancer in patients who are ineligible for therapy with 177Lu-PSMA617." Total funding will be $278,802.
Niharika Mettu of Oncology has received an award from Takeda Development Center Americas, Inc for a project entitled "A Phase 1/2, First-in-Human, Open-Label, Dose-Escalation Study of TAK-280 in Patients With Unresectable Locally Advanced or Metastatic Cancer." Total funding will be $1,418,691.
Richard Riedel of Oncology has received an award from Intensity Therapeutics, Inc. for a project entitled "A Multicenter, Randomized, Phase 3 Study to Assess the Efficacy and Safety of INtratumorally Administered INT230-6 (SHAO, VINblastine, CIsplatin) Compared With US Standard of Care in Adult Participants With Locally Recurrent, InoperaBLE,orMetastatic." Total funding will be $258,414.
April Salama of Oncology has received an award from Regeneron Pharmaceuticals, Inc. for a project entitled "A Phase 2 Peri-operative Trial of Fianlimab and Cemiplimab Compared with Pembrolizumab in Patients with Resectable Stage III and IV Melanoma R3767-ONC-2208." Total funding will be $1,372,692.
Jeffrey Shevach of Oncology has received an award from AstraZeneca AB for a project entitled "A Randomized, 2-cohort, Double-blind, Placebo-controlled, Phase III Study of AZD5305 in Combination with Physician's Choice New Hormonal Agents in Patients with HRRm and non-HRRm Metastatic Castration-Sensitive Prostate Cancer (EvoPAR-Prostate01)." Total funding will be $1,008,513.
Jason Somarelli of Oncology has received an award from Sutro Biopharma, Inc. for a project entitled "Use of FOLR1-targeting antibody drug conjugate in osteosarcoma." Total funding will be $16,110.
John Strickler of Oncology has received an award from Quanta Therapeutics, Inc. for a project entitled "Study drug QTX3046 for KRAS G12D mutated advanced solid tumors." Total funding will be $929,013.
John Strickler of Oncology has received an award from AbbVie Inc. for a project entitled "AndroMETa-CRC-064: An Open Label, Randomized, Controlled, Global Phase 3 Study Comparing ABBV-400 Monotherapy to LONSURF (Trifluridine and Tipiracil) plus Bevacizumab in Subjects with c-Met Over-Expressed Refractory Metastatic Colorectal Cancer (M24-." Total funding will be $344,920.
Sponsored Research
Manesh Patel of Cardiology has received an award from the The SCAN Foundation for a project entitled "Advancing the Safe, Effective, and Equitable use of AI Within the California Safety Net." Total funding will be $100,000.
Jonathan Piccini of Cardiology has received an award from the Icahn School of Medicine at Mount Sinai for a project entitled "Ultra-HFIB." Total funding will be $34,150.
Wenxin Tong (Mentor: Rana Gupta) of Endocrinology has received an award from the American Diabetes Association for a project entitled "Adaptations of the Adipose Tissue Mesothelium in Diet-Induced Obesity." Total funding will be $222,732.
Gowthami Arepally of Hematology has received an award (2R01-HL151730-05) from the National Institutes of Health for a project entitled "Complement and thrombosis in HIT." Total funding will be $2,900,729.
Julie Steinbrink of Infectious Diseases has received an award (1K23-AI187748-01) from the National Institutes of Health for a project entitled "Novel Host-Response Biomarker Diagnostics for Invasive Aspergillosis." Total funding will be $903,776.
Nathan Thielman of Infectious Diseases has received a sub-award (4R33-TW011667-03) through the University of South Carolina for a project entitled "CONSORT." Total funding will be $188,502.
Nathan Thielman of Infectious Diseases has received a sub-award (5-D43TW012274-03) through the University of Maryland, Baltimore for a project entitled "Evaluation of etiology, management, and risk factors among patients with acute upper gastrointestinal bleeding at a tertiary care center in Northern Tanzania: a prospective cohort study." Total funding will be $101,510.
Eziafa Oduah of Oncology has received an award from the Lung Cancer Initiative of North Carolina for a project entitled "Investigating the impact of intratumoral PCSK9 on antigen presentation in NSCLC." Total funding will be $150,000.
Christina Barkauskas of Pulmonary has received a sub-award (5U01-HL168478-02) through the Intermountain Healthcare for a project entitled "ARDS, Pneumonia, and Sepsis Phenotyping Consortium Clinical Centers (APS)_Fixed Budget." Total funding will be $1.
Alexander Graham of Pulmonary has received an award from the Cystic Fibrosis Foundation for a project entitled "Identifying acute lung allograft dysfunction in lung transplant recipients and evaluating its relationship in developing chronic lung allograft dysfunction." Total funding will be $55,933.
Jamie Todd of Pulmonary has received an award from the Cystic Fibrosis Foundation for a project entitled "Transcriptional profiling of allograft tissues to define endotypes associated with CLAD progression." Total funding will be $168,000.
Industry Sponsored Clinical Trials
Ravi Karra of Cardiology has received an award from Intellia Therapeutics, Inc. for a project entitled "Magnitude." Total funding will be $351,125.
Michel Khouri of Cardiology has received an award from AstraZeneca AB for a project entitled "MaesTTRo A Non-interventional, Prospective, Multi-country Study Collecting Real-world Data on the Characteristics, Treatment Patterns, and Outcomes of Patients with Amyloid Transthyretin (ATTR) Amyloidosis." Total funding will be $364,460.
Renato Lopes of Cardiology has received an award from Opthea Limited for a project entitled "A Phase 3 Clinical Program Consisting of Two Multicenter, Double-Masked, Randomized, Sham-Controlled Trials COAST (Combination OPT-302 with Aflibercept Study) and ShORe (Study of OPT-302 in Combinatio." Total funding will be $378,987.
Jennifer Rymer of Cardiology has received an award from Abbott Vascular, Inc for a project entitled "Cath PCI Industry." Total funding will be $75,000.
John Strouse of Hematology has received an award from Pfizer, Inc. for a project entitled "Duke Comprehensive Sickle Cell Center Fellowship." Total funding will be $100,000.
Mehri McKellar of Infectious Diseases has received an award from Gilead Sciences, Inc. for a project entitled "A Phase 3, Randomized, Open-Label, Active-Controlled Study to Evaluate a Switch to an Oral Weekly Islatravir/Lenacapavir Regimen in People With HIV-1 Who Are Virologically Suppressed on Standard of Care." Total funding will be $236,679.
Mehri McKellar of Infectious Diseases has received an award from Gilead Sciences, Inc. for a project entitled "ISLEND-1 A Phase 3, Randomized, Double-blind, Active-controlled Study to Evaluate a Switch to an Oral Weekly Islatravir/Lenacapavir Regimen in People With HIV-1 Who Are Virologically Suppressed on Bictegravir/Emtricitabine/Tenofovir (B/F/TAF)." Total funding will be $224,760.
Laura Alder of Oncology has received an award from ORIC Pharmaceuticals, Inc. for a project entitled "An Open-Label, Phase 1/2 Study of ORIC-114 as a Single Agent or in Combination with Chemotherapy, in Patients with Advanced Solid Tumors Harboring an EGFR or HER2 Alteration." Total funding will be $541,619.
Jeffrey Clarke of Oncology has received an award from Amgen, Inc. for a project entitled "A Phase 3, Open-label, Multicenter, Randomized Study of Tarlatamab in Combination With Durvalumab vs Durvalumab Alone in Subjects with Extensive-Stage Small-Cell Lung Cancer Following Platinum, Etoposide and Durvalumab (DeLLphi-305)." Total funding will be $1,102,456.
Niharika Mettu of Oncology has received an award from Revolution Medicines, Inc for a project entitled "RASolute 302: A Phase 3 Multicenter, Open-label, Randomized Study of RMC-6236 versus Investigator?s Choice of Standard of Care Therapy in Patients with Previously Treated Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)." Total funding will be $676,740.
Jason Somarelli of Oncology has received an award from Dolphin Quest for a project entitled "Multi-scale physiological and behavioral responses of bottlenose dolphin to novel anthropogenic sounds." Total funding will be $8,500.
John Strickler of Oncology has received an award from Revolution Medicines, Inc for a project entitled "RMC-6236 plus 5-flourouracil-based regimens in Patients with Unresectable or Metastatic Colorectal Cancer or Metastatic Pancreatic Ductal Adenocarcinoma- Subprotocol A." Total funding will be $1,471,334.
John Strickler of Oncology has received an award from Phanes Therapeutics, Inc. for a project entitled "A Phase 1/2, Open-Label, Dose Escalation and Expansion Study with PT886 followed by a Multi-cohorT Study in Patients With Advanced GastrIc, Gastroesophageal JuNction (GEJ), or Pancreatic Ductal AdEnocarcinomas of PT886, in Combination with either Che." Total funding will be $892,103.
John Strickler of Oncology has received an award from Revolution Medicines, Inc for a project entitled "RMC-6236 + gemcitabine and nab-paclitaxel for pancreatic cancer (RMC-GI-102_C)." Total funding will be $839,942.
John Strickler of Oncology has received an award from Revolution Medicines, Inc for a project entitled "Study of RMC-6236 in Combination with Cetuximab with or without mFOLFOX6 in Patients with Unresectable or Metastatic Colorectal Cancer or Metastatic Pancreatic Ductal Adenocarcinoma - Subprotocol B." Total funding will be $641,111.
Lake Morrison of Pulmonary has received an award from GlaxoSmithKline for a project entitled "BEconneCTD-ILD (BElimumab for conneCtive Tissue Disease ILD)] Phase 3, randomized, double-blind, placebocontrolled, parallel group study to evaluate the efficacy and safety of belimumab administered subcutaneously in adults with interstitial lung di." Total funding will be $121,887.