New funding awards - October 2016

Sponsored Research

Robert J. Mentz of Cardiology has received an award (3U10-HL084904-10S1) from the National Heart, Lung, and Blood Institute for a project entitled "Characterizing HIV-related Diastolic Dysfunction.

L. Kristin Newby of Cardiology has received an award (1U2C-OD023375-01) from the National Institutes of Health for a project entitled "ECHO Steering Committee Support and Communications Component", a part of Phillip B. Smith's project entitled "ECHO Coordinating Center." Total funding will be $11,283,120.

Gillian D. Schmidler of Cardiology has received an award (HHSA290201500004I-TO8) from the Agency for Healthcare Research and Quality for a project entitled "EPC V TO #33 Women's Health." Total funding will be $125,000.

Gillian D. Schmidler of Cardiology has received an award from the Patient-Centered Outcomes Research Institute for a project entitled "Topic Refinement, Task order 9 Topic Briefs." Total funding will be $7,972.

Gillian D. Schmidler of Cardiology has received an award from the Patient-Centered Outcomes Research Institute for a project entitled "Topic Refinement, Task order 8 PCSK9." Total funding will be $56,211.

James W. Wisler of Cardiology has received an award from the American College of Cardiology Foundation for a project entitled "Molecular mechanisms of aortic aneurysm development." Total funding will be $70,000.

Diego Bohorquez of Gastroenterology has received an award from the Dana Foundation for a project entitled "Illuminating a gut-brain neural path for sensory signaling and pathogens." Total funding will be $200,000.

Matthew L. Maciejewski of General Internal Medicine has received an award (1R01-DA040056-01A1) from the National Institutes of Health for a project entitled "Long-term Mental Health Outcomes of Bariatric Surgery." Total funding will be $2,281,909.

Luigi Racioppi of Hematological Malignancies and Cellular Therapy has received a sub-award (5U19-AI067773-12) through the Columbia University for a project entitled "Determining the mechanism of the protective of action of STO-609, a CaMKK2 inhibitor, in acute radiation syndrome." Total funding will be $106,000.

Deverick J. Anderson of Infectious Diseases has received an award (4UM1-AI104681-04) from the National Institutes of Health for a project entitled "Consortium on Resistance Against Carbapenems in Klebsiella pneumoniae and Other Enterobacteriaceae (CRACKLE): a Prospective, Observational Cohort Study."

John A. Bartlett of Infectious Diseases has received an award (3D43-TW009595-04S1) from the National Institutes of Health for a project entitled "Sociobehavioral Sciences Research to Improve Care for HIV Infection in Tanzania." Total funding will be $101,234.

Elizabeth S. Dodds Ashley of Infectious Diseases has received an award (200-2016-91776-Domain 2--TO1) from the Centers for Disease Control and Prevention for a project entitled "Improving antibiotic use through implementation and evaluation of Core Elements of Hospital Antibiotic Stewardship Programs (Domain 2)." Total funding will be $2,991,241.

Chris Woods of Infectious Diseases has received an award (W81XWH-16-C-0147) from the Department of Defense for a project entitled "Novel host-based diagnostics of febrile illness in the warfighter." Total funding will be $1,191,127.

Jennifer A. Freedman of Medical Oncology has received an award (1P20-CA202925-01A1) from the National Institutes of Health for a project entitled "Interrogation and modulation of novel race-related alternatively spliced androgen receptor target genes in prostate cancer", a part of Steven Patierno's project entitled "2/2 NCCU-DUKE Cancer Disparities Translational Research Partnership." Total funding will be $156,243.

Steven Patierno of Medical Oncology has received an award (1P20-CA202925-01A1) from the National Institutes of Health for a project entitled "Administrative Core." Total funding will be $788,318.

Industry-sponsored Clinical Trials

Scott J. Denardo of Cardiology has received an award from the Amgen, Inc. for a project entitled "PRIME-HF Lumberton." Total funding will be $81,850.

Adrian F. Hernandez of Cardiology has received an award from the Novartis Pharma AG for a project entitled "Novartis LACan: Heart Failure." Total funding will be $47,819.

Raymond J. Kim of Cardiology has received an award from the Siemens Medical Solutions USA, Inc. for a project entitled "Duke Kim Cardiac AAR MR." Total funding will be $29,993.

Mitchell W. Krucoff of Cardiology has received an award from the Biosensors Research USA, Inc. for a project entitled "Biosensors Registry for BioFreedom Drug Coated Stent (DCS) - LOI." Total funding will be $940,519.

Renato D. Lopes of Cardiology has received an award from the Eli Lilly and Company for a project entitled "GBGJ Dulaglutide CEC." Total funding will be $88,802.

Robert J. Noveck of Cardiology has received an award from the Eli Lilly and Company for a project entitled "A Multiple-Dose, Dose-Escalation Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of LY3041658 in Patients with Neutrophilic Skin Diseases." Total funding will be $425,278.

Manesh R. Patel of Cardiology has received an award from the Procyrion, Inc. for a project entitled "Procyrion FIM Device Study." Total funding will be $209,083.

Eric D. Peterson of Cardiology has received an award from the American Heart Association for a project entitled "Get With The Guidelines Registry." Total funding will be $1,967,316.

Matthew T. Roe of Cardiology has received an award from the MyoKardia, Inc. for a project entitled " MYK-461-004: Phase 2a and 2b Program." Total funding will be $227,741.

Pierluigi Tricoci of Cardiology has received an award from the CSL Behring LLC for a project entitled "CSL 112-2001." Total funding will be $52,899.

Manal F. Abdelmalek of Gastroenterology has received an award from the Gilead Sciences, Inc. for a project entitled "GILEAD 426-3989 A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety, Tolerability, and Efficacy of GS-0976 in Subjects with Nonalcoholic Steatohepatitis." Total funding will be $93,995.

Manal F. Abdelmalek of Gastroenterology has received an award from the Conatus Pharmaceuticals for a project entitled "Conatus IDN 6556-14 A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of Emricasan, an Oral Caspase Inhibitor, in Subjects with Non-Alcoholic Steatohepatitis (NASH) Cirrhosis and Severe Porta." Total funding will be $216,605.

Mitchell E. Horwitz of Hematological Malignancies and Cellular Therapy has received an award from the Gamida Cell Ltd for a project entitled "A Multicenter, Randomized, Phase III Registratoin Trial of Transplantation of NiCord, Ex Vivo Expanded, Umbilical Cord Blood-derived, Stem and Progenitor Cells, versus Unmanipulated Umbilical Cord Blood for patients with Hematological Malignancies." Total funding will be $1,004,898.

David Rizzieri of Hematological Malignancies and Cellular Therapy has received an award from the Astex Therapeutics Ltd. for a project entitled "A Phase 3, Multicenter, Randomized, Open-Label Study of Guadecitabine (SGI-110) versus Treatment Choice in Adults with Myelodysplastic Syndromes (MDS) or Chronic Myelomonocytic Leukemia (CMML) Previously Treated with Hypomethylating Agents." Total funding will be $320,764.

Thomas L. Ortel of Hematology has received an award from the Dimension Therapeutics, Inc. for a project entitled "A Phase I/II Open-Label Safety and Dose-Finding Study of Adeno- Associated Virus (AAV) rh10-Mediated Gene Transfer of Human Factor IX in Adults With Moderate/Severe to Severe Hemophilia B." Total funding will be $62,260.

Micah T. McClain of Infectious Diseases has received an award from the GlaxoSmithKline for a project entitled "A Phase II, global, randomized study to evaluate the efficacy and safety of Danirixin (GSK 1325756) co-administered with a standard-of-care antiviral (oseltamivir), in the treatment of adults hospitalized with infuenza." Total funding will be $6,500.

Chris Woods of Infectious Diseases has received an award from the Institute for Medical Research, Inc. for a project entitled "PSA- Barlett Humphries." Total funding will be $24,257.

Michael R. Harrison of Medical Oncology has received an award from the Argos Therapeutics, Inc. for a project entitled "A Phase III Randomized Study of Autologous Dendritic Cell Immunotherapy (AGS-003) Plus Standard Treatment for Advanced RCC." Total funding will be $184,251.

Niharika B. Mettu of Medical Oncology has received an award from the Incyte Corporation for a project entitled "A Phase 1/2 study of exploring the safety tolerablility and efficacy of Epacadostat in combination with Durvalumab in subjects with selected advanced solid tumors." Total funding will be $200,394.

Syed Y. Zafar of Medical Oncology has received a sub-award (1R42-CA210699-01) through the Vivor, LLC for a project entitled "PAPNavigator STTR (Fast-Track)." Total funding will be $84,922.

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