New funding awards - September 2012

By ajz6@dhe.duke.edu
Department of Medicine faculty have received notice of the following research, clinical trials, CME or other training awards. [tabs style="vertical"] [tab title="Sponsored research"]Robert M. Califf of Cardiology has received an award (2KL2-TR000437-06A1) from the National Institutes of Health for a project entitled "Duke CTSA-KL2." Total funding will be $179,816. Robert M. Califf of Cardiology has received an award (2UL1-TR000436-06A1) from the National Institutes of Health for a project entitled "Duke CTSA." Total funding will be $1,999,999. Pamela S. Douglas of Cardiology has received an award from the Food and Drug Administration for a project entitled "Data Concepts and Terminology Standards in Cardiovascular Imaging (R24)." Total funding will be $149,908. Geoffrey S. Ginsburg of Cardiology has received an award (N66001-09-C-2082) from the Defense Advanced Research Projects Agency for a project entitled "Clinico-Molecular Predictors of Presymptomatic Infectious Disease - Phase II." Total funding will be $84,501. Michael D. Gunn of Cardiology has received an award (2U01-ES017219-04) from the National Institutes of Health for a project entitled "Development of therapeutics for chlorine-induced airway and lung injury." Total funding will be $4,131,050. Eric Velazquez of Cardiology has received a sub-award (SRI infrastructure) through Indiana University for a project entitled "Indiana University Intramural Grant - Genetic Biorepsitory." Total funding will be $11,740. John P. Chute of Hematological Malignancies and Cellular Therapy has received an award (U19- AI067798-08-08S1) from the National Institutes of Health for a project entitled "Translational Studies of Recombinant Pleiotrophin for Radiation Mitgation." Total funding will be $1,048,100. J. Brice Weinberg of Hematology has received an award from the American Society of Hematology for a project entitled "ASH Trainee Award: Autoimmunity and chronic lymphocytic leukemia." Total funding will be $5,000. John A. Bartlett of Infectious Diseases has received an award (D43-TW006732-08S1) from the National Institutes of Health for a project entitled "AIDS International Training and Research Program-Supplement." Total funding will be $100,000. John Perfect of Infectious Diseases has received an award (5R01-AI093257-02) from the National Institutes of Health for a project entitled "Evolution of Cryptococcus neoformans strains from patients with HIV/AIDS." Total funding will be $172,301. Steve M. Taylor of Infectious Diseases has received an award (7K08-AI100924-02) from the National Institutes of Health for a project entitled "Molecular Pathogenesis and Genetic Diversification of Childhood Falciparum Malari." Total funding will be $618,562. Michelle Winn of Nephrology has received an award (1R01- DK094987-01A1) from the National Institutes of Health for a project entitled "Gene Discovery in Autosomal Dominant Focal Segmental Glomerulosclerosis." Total funding will be $659,485. Mark A. Stacy of Neurology has received an award from the National Parkinson Foundation for a project entitled "Center of Excellence Letter of Agreement." Total funding will be $60,000. Kimberly L. Blackwell of Medical Oncology has received an award from Johns Hopkins University for a project entitled "A Phase II Trial of HKI-272 (Neratinib) for Patients with Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Breast cancer and Brain Metastases." Total funding will be $13,664. Mark Lanasa of Medical Oncology has received an award from the V Foundation for Cancer Research for a project entitled "Genetic determinants of progression in chronic lymphocytic leukemia." Total funding will be $600,000. Tereza Martinu of Pulmonary, Allergy and Critical Care Medicine has received an award from the International Society for Heart & Lung Transplantation for a project entitled "Importance of Th17 versus Th2 and Th1 polarization in alloimmune airway fibrosis." Total funding will be $80,000. Virginia B. Kraus of Rheumatology and Immunology has received an award (W81XWH-12-1-0622) from the Department of Defense for a project entitled "Assessment of Biomarkers Associated with Joint Injury and Subsequent Post-Traumatic Arthritis." Total funding will be $341,583. Virginia B. Krausof Rheumatology and Immunology has received a sub-award (2R01-AR052873-07A1) through the New York University School of Medicine for a project entitled "Subcontract NYU to Duke - Leukocyte Gene Expresssion and Genetic Biomarkers of OA Incidence and Progression." Total funding will be $42,103.[/tab] [tab title="Industry-sponsored clinical trials"]James P. Daubert of Cardiology has received an award from Biosense Webster, Inc for a project entitled "THERMOCOOL SMARTTOUCH Catheter for the Treatment of Symptomatic Paroxysmal Atrial Fibrillation SMART-AF - Continued Access Protocol." Total funding will be $186,695. Pamela S. Douglas of Cardiology has received an award from Ikaria, Inc for a project entitled "Chronic Toxicity Study of IK-5001 Delivered via Intracoronary Catheter in Yucatan Pigs following Myocardial Infaction." Christopher Granger of Cardiology has received an award from Boehringer Ingelheim Pharmaceuticals, Inc. for a project entitled "Atrial Fibrillation." Total funding will be $50,000. Kevin P. Jackson of Cardiology has received an award from Biotronik, Inc. for a project entitled "Echocardiography Guided Cardiac Resynchronization Therapy Clinical Investigation." John R. Guyton of Endocrinology, Metabolism and Nutrition has received an award from Merck Sharp & Dohme for a project entitled "HeFH anacetrapib Study, MK-0859-020." Total funding will be $216,480. Wei Chen of Gastroenterology has received an award from mAbRx, Inc. for a project entitled "Development of a monoclonal antibody against the "Smoothened" GPCR Target." Total funding will be $12,000. Andrew J. Muir of Gastroenterology has received an award from Achillion Pharmaceuticals, Inc. Total funding will be $1,115,117. Hayden B. Bosworth of General Internal Medicine has received an award from the Institute for Medical Research, Inc. for a project entitled "PSA-Celine Koropchak." Total funding will be $59,378. G. Ralph Corey of Infectious Diseases has received an award from Biocryst Corporation for a project entitled "FRA between G.Ralph Corey and BioCryst." Total funding will be $7,499. Melissa D. Johnson of Infectious Diseases has received an award from the World Health Information Science Consultants, LLC for a project entitled "A Multicenter Cohort Study of the Short and Long-term Safety of Parenteral Antifungal Agents." Total funding will be $447,299. Susanna Naggie of Infectious Diseases has received an award from Gilead Sciences, Inc. for a project entitled "GS-7977 + Ribavirin for 12 wks effect on Genotype 2, HCV and HIV co infected patients." Chris Woods of Infectious Diseases has received an award from Cubist Pharmaceuticals, Inc. for a project entitled "A Randomized, Double-Blinded, Active Controlled Study of CB- 183,315 in Patients with Clostridium Difficile Associated Diarrhea, LCD-CDAD-11-06." John P. Middleton of Nephrology has received an award from Keryx Biopharmaceuticals Inc for a project entitled "KEREX-0502-307 - A Long Term Safety Extension Trial of KRX-0502 in Patients with ESRD." Total funding will be $26,136. Tulika Ranjan of Neurology has received an award from Eli Lilly and Company for a project entitled "A Phase 2 Study of LY2157299 Monohydrate Monotherapy or LY2157299 Monohydrate plus Lomustine therapy compared to Lomustine Monotherapy in Patients with Recurent Glioblastoma - H9H-MC-JBAL." Total funding will be $147,606. Kimberly L. Blackwell of Medical Oncology has received an award from the Dana-Farber Cancer Institute for a project entitled "A Phase II Trial of HKI-272 (Neratinib) for Patients with Human Epidermal Growth Factor Receptor 2 (HER2)- Positive Breast Cancer Positive Breast cancer and Brain Metastases." Total funding will be $7,641. Kimberly L. Blackwell of Medical Oncology has received an award from F. Hoffmann-La Roche Ltd for a project entitled "A two-cohort, open-label, multicenter Phase II trial assessing the efficacy and safety of pertuzumab given in combination with trastuzumab and vinorelbine in first line patients with HER2-positive advanced metastatic or locally advanced breast cancer." Total funding will be $44,696. Mark Lanasa of Medical Oncology has received an award from AbbVie Inc. for a project entitled "A Phase 1b Study Evaluating The Safety and Tolerability of ABT-199 in Combination with Rituximab in Subjects with Relapsed Chronic Lymphocytic Leukemia (M13-365)." Total funding will be $342,472. Neal E. Ready of Medical Oncology has received an award from Bristol-Myers Squibb for a project entitled "An Open-label randomized Phase II trial of BMS-936558 versus Docetaxel in Previously Treated Metastatic Non-Squamous Cell Lung Cancer (NSCLC)." Neal E. Ready of Medical Oncology has received an award from Bristol-Myers Squibb for a project entitled "An Open-label Randomized Phase III trial of BMS-936558 versus Docetaxel in previously treated advanced or Metastatic Squamous Cell Non-small Cell Lung Cancer." Total funding will be $128,435. April K. Salama of Medical Oncology has received an award from Bristol-Myers Squibb for a project entitled "A single arm open-label phase II study of Vemurafenib followed by a continuous administration of Ipilimumab in subjects." Total funding will be $116,758. Neil L. Spector of Medical Oncology has received an award from Synta Pharmaceuticals Corp. for a project entitled "An open label multicenter Phase 2 window of opportunity study evaluating Ganetespib (STA-9090) monotherapy in women with previously untreated Metastatic HER2 positive or Triple Negative Breast Cancer." Total funding will be $107,060. Lesley H. Curtis of Other Medicine has received an award from GlaxoSmithKline for a project entitled "Long-term Treatment Patterns in Age-related Macular Degeneration (AMD)." Total funding will be $167,167. Monica Kraft of Pulmonary, Allergy and Critical Care Medicine has received an award from Genentech, Inc. for a project entitled "SOW # GB27864 Genentech, Inc." Scott M. Palmer of Pulmonary, Allergy and Critical Care Medicine has received an award from Bristol-Myers Squibb for a project entitled "Lysophosphatidic acid receptor-1 antagonist." Total funding will be $75,520. John S. Sundy of Pulmonary, Allergy and Critical Care Medicine has received an award from Savient Pharmaceuticals, Inc. for a project entitled "Observational Study of the Use of KRYSTEXXA (pegloticase) in Adult Hyperuricemic Patients with Gout Refractory to Conventional Therapy." Total funding will be $72,495. Momen Wahidi of Pulmonary, Allergy and Critical Care Medicine has received an award from Aeris Therapeutics, Inc. for a project entitled "(Aspire) Aeriseal system study on Emphysema See attached CTA , Protocol and Budget attached." Total funding will be $23,709. Nancy B. Allen of Rheumatology and Immunology has received an award from Genentech, Inc. for a project entitled "WA27893 Prospective, Observational Safety Study of Patients with Wegener's Granulomatosis (WG) (Granulomatosis with Polyangitis) or Microscopic Polyangitis (MPA) Treated with Rituximab." Total funding will be $149,807.[/tab] [/tabs]

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