Department of Medicine faculty have received notice of the following research, clinical trials, CME or other training awards.
[tabs style="vertical"][tab title="Sponsored research"]Robert M. Califf of Cardiology has received an award (3UL1-TR001117-02 -S2) from the National Institutes of Health for a project entitled "Duke CTSA (UL1) - Education Supplement." Total funding will be $71,747.
Robert M. Califf of Cardiology has received an award (1R18-FD005292-01) from the Food and Drug Administration for a project entitled "Increasing the Quality and Efficiency of Clinical Trials (R18)." Total funding will be $37,499,986.
Gillian D. Schmidler of Cardiology has received an award from the Patient-Centered Outcomes Research Institute for a project entitled "PCORI Triage and FR Prioritization - Amendment #5." Total funding will be $18,000.
Gillian D. Schmidler of Cardiology has received an award from the Agency for Healthcare Research and Quality for a project entitled "Evidence-based Practice Centers (EPC) V Task D.2.1, D.2.2."
Galen S. Wagner of Cardiology has received an award from the Oak Ridge Institute for Science and Education for a project entitled "Research Participation Program ORISE/FDA." Total funding will be $19,464.
David D'Alessio of Endocrinology, Metabolism, and Nutrition has received an award (1R01-DK101991-01) from the National Institutes of Health for a project entitled "Incretin Action in Physiology and Diabetes." Total funding will be $1,764,425.
Laura M. Beskow of General Internal Medicine has received an award (1R01-LM012178-01) from the National Institutes of Health for a project entitled "Ethical Approaches to Research Use of Clinical Records and Data." Total funding will be $1,138,300.
Leigh Boulware of General Internal Medicine has received an award (R34-DK094116) from the National Institutes of Health for a project entitled "Decision support interventions to improve renal replacement therapy preparation." Total funding will be $178,004.
Juliessa M. Pavon of Geriatrics has received an award (1R01-AG048007-01) from the National Institutes of Health for a project entitled "Adherence to Venous Thromboembolism Prophylaxis Guidelines in Hospitalized Elders." Total funding will be $236,876.
Jun Chen of Hematological Malignancies and Cellular Therapy has received an award (HHSN272201400034C) from the Department of Health and Human Services for a project entitled "A Novel Nanoparticle Platelet Analogue for Radiation-Induced Thrombocytopenia." Total funding will be $1,907,479.
John A. Bartlett of Infectious Diseases has received an award from Wake County Human Services for a project entitled "HIV Adult ID Services through Wake County, Year 6." Total funding will be $147,644.
Greg Gray of Infectious Diseases has received an award (5 D43-TW009373-02) from the National Institutes of Health for a project entitled "One Health Innovation Fellowships for Zoonotic Disease Research in Mongolia." Total funding will be $1,259,244.
Mehri McKellar of Infectious Diseases has received a sub-award (5U62-PS0003977-) through the NC Dept of Health and Human Services for a project entitled "Care and Prevention in the United States (CAPUS), Patient Navigator Project." Total funding will be $62,500.
Mehri McKellar of Infectious Diseases has received an award from the NC DHHS for a project entitled "Substance Abuse Center-5 (SAC-5): Counseling, Testing and Referral in Durham, Caswell, Orange, Person and Wake." Total funding will be $50,000.
Mehri McKellar of Infectious Diseases has received an award from the NC DHHS for a project entitled "Healthy Relationships: Region Seven Prevention for Positives." Total funding will be $60,000.
Wendy A. Prudhomme - O'Meara of Infectious Diseases has received an award from the National Institutes of Health for a project entitled "Innovative partnership to target antimalarial subsidies in the retail sector." Total funding will be $1,973,300.
Nathan M. Thielman of Infectious Diseases has received a sub-award (5R25-TW009337-03) through Vanderbilt University for a project entitled "Vanderbilt-Emory-Cornell-Duke Consortium for Global Health Fellows (VECDor)." Total funding will be $34,251.
Nathan M. Thielman of Infectious Diseases has received a sub-award (5R25-TW009337-03) through Vanderbilt University for a project entitled "Vanderbilt-Emory-Cornell-Duke Consortium for Global Health Fellows (VECDor)." Total funding will be $36,715.
Nathan M. Thielman of Infectious Diseases has received a sub-award (r25-TW009337-03) through Vanderbilt University for a project entitled "Vanderbilt-Emory-Cornell-Duke Consortium for Global Health Fellows (VECDor)." Total funding will be $18,684.
Andrew Armstrong of Medical Oncology has received an award from the Prostate Cancer Foundation for a project entitled "Development of Circulating Molecular Predictors of Chemotherapy and Novel Hormonal Therapy Benefit in Men with Metastatic Castration Resistant Prostate Cancer (mCRPC)." Total funding will be $1,170,797.
Daniel J. George of Medical Oncology has received an award (PC131800-W81XWH-14-2-0179) from the Department of Defense for a project entitled "PCRP Clinical Consortium: Duke University Clinical Research Site." Total funding will be $942,000.
Brent A. Hanks of Medical Oncology has received a sub-award (U01-CA154967-04) through the Fred Hutchinson Cancer Research Center for a project entitled "A phase II, open-label, multicenter, randomized study of CDX-1401 a Dendritic Cell targeting NY-ESO-1 vaccine, in patients with malignant melanoma pre-treated with recombinant CDX-301, a recombinant human F1t3 ligand." Total funding will be $42,000.
Steven Patierno of Medical Oncology has received an award (W81XWH-14-1-0569) from the Department of Defense for a project entitled "Validation and interrogation of differentially expressed and alternatively spliced genes in African American prostate cancer." Total funding will be $820,658.
Thomas M. Coffman of Nephrology has received an award (3P30-DK096493-03S1) from the National Institutes of Health for a project entitled "Student Supplement." Total funding will be $30,240.
Susan B. Gurley of Nephrology has received a sub-award (2R01-HL073085-10A1) through the University of Kentucky for a project entitled "ACE2 and Abdominal Aortic Aneurysms." Total funding will be $3,861.
Uptal Patel of Nephrology has received an award (1R34-DK102166-01) from the National Institutes of Health for a project entitled "Integrated Population Program for Diabetic Kidney Disease." Total funding will be $706,876.
Alice L. Gray of Pulmonary, Allergy, and Critical Care Medicine has received an award from the Cystic Fibrosis Foundation for a project entitled "CFF." Total funding will be $21,170.
Monica Kraft of Pulmonary, Allergy, and Critical Care Medicine has received a sub-award (5U10-HL098115-08) through the University of Arizona for a project entitled "Steroids In Eosinophil Negative Asthma - SIENA." Total funding will be $288,780.
Monica Kraft of Pulmonary, Allergy, and Critical Care Medicine has received an award (1R56-HL126537-01) from the National Institutes of Health for a project entitled "HIV and Asthma in the Post- ART Era." Total funding will be $729,181.
Harvey Marshall of Pulmonary, Allergy, and Critical Care Medicine has received an award (2R01-HL092994-05) from the National Institutes of Health for a project entitled "S-nitrosothiols, NF-KappaB and Inflammation in Acute Lung Injury." Total funding will be $1,584,167.
Scott M. Palmer of Pulmonary, Allergy, and Critical Care Medicine has received an award (1R21-OH010490-01A1) from the Centers for Disease Control and Prevention for a project entitled "Proteomics of flavorings-induced airway disease." Total funding will be $429,368.[/tab][tab title="Industry-sponsored clinical trials"]John K. Harrison of Cardiology has received an award from Medtronic, Inc. for a project entitled "EVOLUT." Total funding will be $835,350.
John K. Harrison of Cardiology has received an award from Direct Flow Medical, Inc for a project entitled "Transcather Aortic Valve Replacement System a US Pivotal Trial." Total funding will be $971,261.
James S. Mills of Cardiology has received an award from MaQuet Cardiovascular for a project entitled "CRISP AMI 2." Total funding will be $13,800.
L. Kristin Newby of Cardiology has received an award from Google Inc. for a project entitled "Google X Baseline Study Travel Agreement." Total funding will be $30,000.
Robert J. Noveck of Cardiology has received an award from Acorda Therapeutics, Inc for a project entitled "A Double-Blind Pharacokinetic Interaction Study Evaluating the Effect of a Single IV Infusion of GGF2 or Placebo on Midazolam Pharmacokinetics in Patients with Heart Failure." Total funding will be $194,570.
Robert J. Noveck of Cardiology has received an award from Drip Drop for a project entitled "A Randomized Trial Comparing the Speed of Onset, Extent of Absorption and Duration of Fluid Retention of Four Different Fluids Used for Re-Hydration Following Moderate Exercise." Total funding will be $310,586.
Manesh R. Patel of Cardiology has received an award from Cardiovascular Systems Inc. for a project entitled "Coronary Orbital Atherectomy System Trial." Total funding will be $80,115.
Manesh R. Patel of Cardiology has received an award from Cardiovascular Systems Inc. for a project entitled "CSI Educational Program Agreement." Total funding will be $4,400.
Jonathan P. Piccini of Cardiology has received an award from Janssen Scientific Affairs, LLC. for a project entitled "ORBIT Manuscripts." Total funding will be $929,660.
Tracy Y. Wang of Cardiology has received an award from Regeneron Pharmaceuticals, Inc. for a project entitled "PALM Registry." Total funding will be $6,757,877.
Andrew J. Muir of Gastroenterology has received an award from NGM Biopharmaceuticals for a project entitled "NGM 14-0104." Total funding will be $94,111.
Keyur Patel of Gastroenterology has received an award from Lumena Pharmaceuticals, Inc. for a project entitled "Lumena PSC." Total funding will be $65,304.
Nelson J. Chao of Hematological Malignancies and Cellular Therapy has received an award from Novartis Pharmaceuticals Corporation for a project entitled "Prevention of Gastrointestinal Toxicity from total body irradiation or high dose Chemo with SOM230." Total funding will be $508,743.
David Rizzieri of Hematological Malignancies and Cellular Therapy has received an award from Novella Clinical for a project entitled "Phase 2, Randomized, Double-Blind, Placebo-Controlled study of Azacitidine with or without Birinapant with a Single Arm Open-Label Run-In Phase in Subjects with Higher Risk Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia." Total funding will be $336,745.
David Rizzieri of Hematological Malignancies and Cellular Therapy has received an award from Avillion Development for a project entitled "A Multicenter Phase III Rand, open-Label, study of Bosutinib vs Imatinib in adults with newly diagnosed CPCML." Total funding will be $100,003.
Thomas L. Ortel of Hematology has received an award from the Canadian Institutes of Health Research for a project entitled "REVERSE - REcurrent VEnouse thromboembolism Risk Stratification Evaluation II: Validaton of the "Men and HERDOO2"-A clinical Decision Rule to Identify Patients with "Unprovoked" VTEs who can Discontinue Anticoagulatnts after 6 months of Treatment." Total funding will be $12,787.
Kimberly L. Blackwell of Medical Oncology has received an award from Genentech, Inc. for a project entitled "A randomized, multicenter, open-label, phase iii trial comparing trastuzumab plus pertuzumab plus a taxane following anthracyclines versus trastuzumab emtansine plus pertuzumab following anthracyclines as adjuvant therapy in patients." Total funding will be $468,428.
Kimberly L. Blackwell of Medical Oncology has received an award from Celldex Therapeutics, Inc. for a project entitled "A Randomized Multicenter Pivotal Study of CDX-011 (CR011-vcMMAE) in Patients with Metastatic, GPNMB Over-Expressing, Triple-Negative Breast Cancer (CDX011-04)." Total funding will be $94,042.
Herbert I. Hurwitz of Medical Oncology has received an award from Incyte Corporation for a project entitled "A randomized double bline phase 3 study of the JAK 1/2 inhibitor Ruxotinib or placebo in conbination with capecitbine in subjects with advanced or metastatic adenocarcinoma of the pancreas." Total funding will be $148,168.
P. Kelly Marcom of Medical Oncology has received an award from Novartis Pharmaceuticals Corporation for a project entitled "A phase ii randomized, double-blind placebo controlled study of letrozole with or without byl719 or buparlisib, for the neoadjuvant treatment of postmenopausal women with hormone receptor-positive her2-negative breast cancer." Total funding will be $109,108.
Michael A. Morse of Medical Oncology has received an award from Onyx Pharmaceuticals, Inc for a project entitled "Phase Ib/2 Study of Oprozomib in combination with Dorafenib in subjects in advanced hepatocellular carcinoma." Total funding will be $402,039.
Michael A. Morse of Medical Oncology has received an award from AlphaVax, Inc. for a project entitled "(Re-Open) study of active immunotherapy with cea(6d) vrp vaccine (avx701) in patients with malignancies expressing cea." Total funding will be $4,237.
Neal E. Ready of Medical Oncology has received an award from the Bristol-Myers Squibb Company for a project entitled "A phase 1 / 2 multicenter study of BMS-986012 in subjects with relapsed/refractory small cell lung cancer." Total funding will be $931,118.
John P. Middleton of Nephrology has received an award from Medpace, Inc for a project entitled "NephroGenex Protocol PRY-311 : A Phase 3 Randomized, Double-Blind,Placebo-Controlled, Multi-Center Study to Evaluate the Safety and Efficacy of Pyridorin (pyridoxamine dihydrochloride) in Subjects With Nephropathy Due to Type 2 Diabetes." Total funding will be $79,615.
Uptal Patel of Nephrology has received an award from Eli Lilly and Company for a project entitled "A Randomized, Double-Masked, Placebo-Controlled, Multicenter, Phase 2 Study to Evaluate the Safety and Renal Efficacy of LY2382770 in Patients with Diabetic Kidney Disease due to Type 1 or Type 2 Diabetes." Total funding will be $455,846.
Lesley H. Curtis of Other Medicine has received an award from the Novartis Pharmaceuticals Corporation for a project entitled "Creating a Risk Model for Worsening Heart Failure." Total funding will be $117,163.
Lesley H. Curtis of Other Medicine has received an award from the Novartis Pharmaceuticals Corporation for a project entitled "Timing of Worsening Heart Failure and Association with Outcomes." Total funding will be $88,722.
David M. Brass of Pulmonary, Allergy, and Critical Care Medicine has received an award from Taiwan Pharmaceuticals Co. Ltd for a project entitled "JK119 for the Prevention and Treatment of Bronchiolitis Obliterans (BO) in a rat model of BO." Total funding will be $118,784.
Megan E. Clowse of Rheumatology and Immunology has received an award from Pfizer, Inc. for a project entitled "ASPIRE - Causes of comorbid infertility among women with rheumatoid arthritis." Total funding will be $150,000.
Lisa G. Criscione-Schreiber of Rheumatology and Immunology has received an award from AbbVie Inc. for a project entitled "Support for a Clinical Fellow - 22483." Total funding will be $50,000.[/tab]
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