Pearls from 12/7/2021

The December 7, 2021, session of Duke Medicine LEADS featured Aaron Hein, MD, Rachel Tobin, MD, James Helzberg, MD with a panel including Michael Mulvihill, MD, Carolyn Glass, MD and Lisa Criscione-Schreiber, MD presenting "A Diagnostic Dilemma of Multifocal Arterial Aneurysms." 

  1. An approach to multiple large vessel aneurysms includes consideration of (1) structural connective tissues disorders which may be syndromic or non-syndromic in nature, (2) infectious etiologies including bacterial, mycobacterial or fungal causes and (3) auto-immune etiologies including large vessel vasculitis. 
  2. Typical classification of vasculitis occurs by vessel size with small vessel disease including ANCA negative vs. ANCA positive disease, medium vessel including polyarteritis nodosa or Kawasaki disease and large vessel including Giant cell arteritis and Takayasu arteritis .
  3. Bechet's Disease commonly presents with recurrent aphthous ulcerations, but is also a rare vasculitis with the unique ability to affect both arterial and venous vessels of all sizes. Bechet's may be associated with hematologic malignancy including Chronic Neutrophilic Leukemia or other malignancies. 
  4. Hughes-Stoven Syndrome (HSS) is a rare subtype of Behcet's disease characterized by aneurysms and thrombosis, usually seen in young adult males.

Watch the recorded session

Duke Medicine Learning, Education, and Discussion Series (LEADS) takes place each Tuesday at 12 p.m. Learn more and see schedule of upcoming sessions.