Harvey Jay Cohen, MD

Professor of Medicine
Walter Kempner Professor of Medicine, in the School of Medicine
Director, Center for the Study of Aging & Human Development
Faculty Research Scholar of DuPRI's Center for Population Health & Aging
Member of the Duke Cancer Institute
Campus mail 3502 Blue Zone Duke Clinic, Center For Aging, Trent Drive, Durham, NC 27710
Phone (919) 660-7502
Email address harvey.cohen@duke.edu

Dr. Cohen's research program includes clinical research relating to aspects of the pathways to functional decline with aging, geriatric assessment, and cancer in the elderly.

Pathways to functional decline are being explored through the NIA funded Claude Pepper Older Americans Independence Center, and includes studies of the contributions of age related physiologic change, in particular changes in inflammatory parameters, comorbid diseases and conditions, environment, genetics, and the interactionas among them. Data are derived from several current studies as well as previously collected data sets from the Established Populations for Epidemiologic Studies of the Elderly (EPESE), National Long Term Care Survey, and the Chinese Longevity Study (with Dr. Zeng Yi). Previous work has demonstrated the important contributions of age related inflammation and coagulation activation to functional status.

Geriatric assessment approaches have been studied in a number of randomized and controlled studies and work is now concentrating on the application of Comprehensive Geriatric Assessment tools to the evaluation and treatment of elderly patients with cancer. This is an extension and continuation of a long standing interest in geriatric oncology. Previous studies have elucidated age-related patterns of disease presentation, treatment approaches, clinical trials, survivorship, quality of life, impact of comrobidities and functional outcomes. Dr. Cohen is co-chair of the Cancer in the Elderly Committee of Cancer and Acute Luekemia Group B (CALGB). A number of active studies and ongoing data bases aree being utilized to address these questions.

Education and Training

  • M.D., State University of New York at Brooklyn, 1965

Publications

Morey, MC, Blair, CK, Sloane, R, Cohen, HJ, Snyder, DC, and Demark-Wahnefried, W. "Group trajectory analysis helps to identify older cancer survivors who benefit from distance-based lifestyle interventions." Cancer 121, no. 24 (December 2015): 4433-4440.

PMID
26512712
Full Text

Pinheiro, SO, White, HK, Buhr, GT, Elbert-Avila, K, Cohen, HJ, and Heflin, MT. "Advancing Geriatrics Education Through a Faculty Development Program for Geriatrics-Oriented Clinician Educators." Journal of the American Geriatrics Society (November 13, 2015).

PMID
26563754
Full Text

Moreira, DM, Bostwick, DG, Andriole, GL, Peterson, BL, Cohen, HJ, Castro-Santamaria, R, and Freedland, SJ. "Baseline Prostate Atrophy is Associated with Reduced Risk of Prostate Cancer in Men Undergoing Repeat Prostate Biopsy." The Journal of urology 194, no. 5 (November 2015): 1241-1246.

PMID
26165588
Full Text

Hurria, A, Levit, LA, Dale, W, Mohile, SG, Muss, HB, Fehrenbacher, L, Magnuson, A, Lichtman, SM, Bruinooge, SS, Soto-Perez-de-Celis, E, Tew, WP, Postow, MA, Cohen, HJ, and American Society of Clinical Oncology, . "Improving the Evidence Base for Treating Older Adults With Cancer: American Society of Clinical Oncology Statement." Journal of clinical oncology : official journal of the American Society of Clinical Oncology 33, no. 32 (November 2015): 3826-3833.

PMID
26195697
Full Text

Wang, X, Gu, L, Zhang, Y, Sargent, DJ, Richards, W, Ganti, AK, Crawford, J, Cohen, HJ, Stinchcombe, T, Vokes, E, and Pang, H. "Validation of survival prognostic models for non-small-cell lung cancer in stage- and age-specific groups." Lung cancer (Amsterdam, Netherlands) 90, no. 2 (November 2015): 281-287.

PMID
26319317
Full Text

Kenzik, KM, Morey, MC, Cohen, HJ, Sloane, R, and Demark-Wahnefried, W. "Symptoms, weight loss, and physical function in a lifestyle intervention study of older cancer survivors." Journal of geriatric oncology 6, no. 6 (November 2015): 424-432.

PMID
26362355
Full Text

"Erratum." Journal of the American Geriatrics Society 63, no. 11 (November 2015): 2445-2445.

Full Text

Owusu, C, Cohen, HJ, Feng, T, Tew, W, Mohile, SG, Klepin, HD, Gross, CP, Gajra, A, Lichtman, SM, Hurria, A, and Cancer and Aging Research Group (CARG), . "Anemia and Functional Disability in Older Adults With Cancer." Journal of the National Comprehensive Cancer Network : JNCCN 13, no. 10 (October 2015): 1233-1239.

PMID
26483063
Full Text

Cohen, HJ. "An Accidental Career in Geriatrics." Journal of the American Geriatrics Society 63, no. 9 (September 2015): 1945-1948.

PMID
26277439
Full Text

Berger, M, Nadler, JW, Browndyke, J, Terrando, N, Ponnusamy, V, Cohen, HJ, Whitson, HE, and Mathew, JP. "Postoperative Cognitive Dysfunction: Minding the Gaps in Our Knowledge of a Common Postoperative Complication in the Elderly." Anesthesiology clinics 33, no. 3 (September 2015): 517-550. (Review)

PMID
26315636
Full Text

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