Nathan Maclyn Thielman, MD

Professor of Medicine
Research Professor of Global Health
Professor of Pathology
Campus mail 310 Trent Drive, Room 201, Trent Hall, Durham, NC 27710
Phone (919) 668-7174

Broadly, my research focuses on a range of clinical and social issues that affect persons living with or at risk for HIV infection in resource-poor settings. In Tanzania, our group is applying novel methods to optimize HIV testing uptake among high-risk groups. We recently demonstrated that the Discrete Choice Experiment (DCE), a form of stated preference survey research, is a robust tool for identifying (a) which characteristics of HIV testing options are most preferred by different populations and (b) which tradeoffs individuals make in evaluating testing options. Building on more than a decade of productive HIV testing research in the Kilimanjaro Region, the next phase of our NIMH funded project will test the hypothesis that DCE-derived HIV testing options significantly increases rates of testing among groups at high risk for HIV infection. This work holds promise not only for optimizing HIV testing uptake in the Kilimanjaro Region, but also for applying novel tools in the service of translational epidemiology and implementation research.

Education and Training

  • Fellow in Infectious Diseases, Medicine, University of Virginia, 1993 - 1996
  • Medical Resident, Medicine, Duke University, 1990 - 1993
  • M.D., Duke University, 1990
  • M.P.H., University of North Carolina - Chapel Hill, 1989

Publications

Zou, James, Yvonne Yamanaka, Muze John, Melissa Watt, Jan Ostermann, and Nathan Thielman. “Religion and HIV in Tanzania: influence of religious beliefs on HIV stigma, disclosure, and treatment attitudes.” Bmc Public Health 9 (March 4, 2009): 75. https://doi.org/10.1186/1471-2458-9-75.

PMID
19261186
Full Text

Crump, John A., Jakko van Ingen, Anne B. Morrissey, Martin J. Boeree, Daudi R. Mavura, Britta Swai, Nathan M. Thielman, et al. “Invasive disease caused by nontuberculous mycobacteria, Tanzania.” Emerg Infect Dis 15, no. 1 (January 2009): 53–55. https://doi.org/10.3201/eid1501.081093.

PMID
19116050
Full Text

Mayhood, Meghan K., Isaac A. Afwamba, Christopher O. Odhiambo, Epimack Ndanu, Nathan M. Thielman, Anne B. Morrissey, John F. Shao, Brian Wells Pence, and John A. Crump. “Validation, performance under field conditions, and cost-effectiveness of Capillus HIV-1/HIV-2 and determine HIV-1/2 rapid human immunodeficiency virus antibody assays using sequential and parallel testing algorithms in Tanzania.” J Clin Microbiol 46, no. 12 (December 2008): 3946–51. https://doi.org/10.1128/JCM.01045-08.

PMID
18923015
Full Text

Pence, Brian Wells, Nathan M. Thielman, Kathryn Whetten, Jan Ostermann, Virender Kumar, and Michael J. Mugavero. “Coping strategies and patterns of alcohol and drug use among HIV-infected patients in the United States Southeast.” Aids Patient Care Stds 22, no. 11 (November 2008): 869–77. https://doi.org/10.1089/apc.2008.0022.

PMID
19025481
Full Text

Seshadri, C., L. O. Uiso, J. Ostermann, H. Diefenthal, H. J. Shao, H. Y. Chu, D. M. Asmuth, N. M. Thielman, J. A. Bartlett, and J. A. Crump. “Low sensitivity of T-cell based detection of tuberculosis among HIV co-infected Tanzanian in-patients.” East Afr Med J 85, no. 9 (September 2008): 442–49. https://doi.org/10.4314/eamj.v85i9.117085.

PMID
19537417
Full Text

Landman, Keren Z., Jan Ostermann, John A. Crump, Anna Mgonja, Meghan K. Mayhood, Dafrosa K. Itemba, Alison C. Tribble, et al. “Gender differences in the risk of HIV infection among persons reporting abstinence, monogamy, and multiple sexual partners in northern Tanzania.” Plos One 3, no. 8 (August 27, 2008): e3075. https://doi.org/10.1371/journal.pone.0003075.

PMID
18728779
Full Text

Morpeth, Susan C., Nathan M. Thielman, Habib O. Ramadhani, John D. Hamilton, Jan Ostermann, Peter R. Kisenge, Humphrey J. Shao, et al. “Effect of trimethoprim-sulfamethoxazole prophylaxis on antimicrobial resistance of fecal Escherichia coli in HIV-infected patients in Tanzania.” J Acquir Immune Defic Syndr 47, no. 5 (April 15, 2008): 585–91. https://doi.org/10.1097/QAI.0b013e31816856db.

PMID
18285712
Full Text

Hanisch, Laura J., Jan Ostermann, Steven C. Palmer, Susan S. Reif, Nathan Thielman, and Kathryn Whetten. “Victimization and clinical outcomes among HIV-infected individuals with co-occurring mental and substance use disorders.” Annals of Behavioral Medicine 35 (March 1, 2008): S45–S45.

Scholars@Duke

Pence, Brian Wells, Jan Ostermann, Virender Kumar, Kathryn Whetten, Nathan Thielman, and Michael J. Mugavero. “The influence of psychosocial characteristics and race/ethnicity on the use, duration, and success of antiretroviral therapy.” J Acquir Immune Defic Syndr 47, no. 2 (February 1, 2008): 194–201. https://doi.org/10.1097/QAI.0b013e31815ace7e.

PMID
17971712
Full Text

Ramadhani, Habib O., Nathan M. Thielman, Keren Z. Landman, Evaline M. Ndosi, Feng Gao, Jennifer L. Kirchherr, Rekha Shah, et al. “Predictors of incomplete adherence, virologic failure, and antiviral drug resistance among HIV-infected adults receiving antiretroviral therapy in Tanzania.” Clin Infect Dis 45, no. 11 (December 1, 2007): 1492–98. https://doi.org/10.1086/522991.

PMID
17990233
Full Text

Pages