Sudarshan Rajagopal, MD, PhD

Assistant Professor of Medicine
Assistant Professor in Biochemistry
Campus mail 3126, Durham, NC 27710
Phone (919) 684-6237
Email address sudarshan.rajagopal@duke.edu
In Their Words

Education and Training

  • Clinical Fellowship, Cardiovascular Disease, Duke University School of Medicine, 2011 - 2013
  • Research Fellowship, Duke University School of Medicine, 2008 - 2011
  • Resident, Internal Medicine, Duke University School of Medicine, 2006 - 2008
  • M.D., University of Chicago, 2006
  • Ph.D., University of Chicago, 2004

Publications

Rajagopal, Sudarshan, Spencer Anderson, Vukica Srajer, Marius Schmidt, Reinhard Pahl, and Keith Moffat. “A structural pathway for signaling in the E46Q mutant of photoactive yellow protein..” Structure (London, England : 1993) 13, no. 1 (January 2005): 55–63. https://doi.org/10.1016/j.str.2004.10.016.

PMID
15642261
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Rajagopal, Sudarshan, Jason M. Key, Erin B. Purcell, David J. Boerema, and Keith Moffat. “Purification and initial characterization of a putative blue light-regulated phosphodiesterase from Escherichia coli..” Photochemistry and Photobiology 80, no. 3 (November 2004): 542–47. https://doi.org/10.1562/2004-06-16-ra-203.

PMID
15453820
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Rajagopal, Sudarshan, Konstantin S. Kostov, and Keith Moffat. “Analytical trapping: extraction of time-independent structures from time-dependent crystallographic data..” Journal of Structural Biology 147, no. 3 (September 2004): 211–22. https://doi.org/10.1016/j.jsb.2004.04.007.

PMID
15450291
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Anderson, Spencer, Vukica Srajer, Reinhard Pahl, Sudarshan Rajagopal, Friedrich Schotte, Philip Anfinrud, Michael Wulff, and Keith Moffat. “Chromophore conformation and the evolution of tertiary structural changes in photoactive yellow protein..” Structure (London, England : 1993) 12, no. 6 (June 2004): 1039–45. https://doi.org/10.1016/j.str.2004.04.008.

PMID
15274923
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Rajagopal, Sudarshan, Marius Schmidt, Spencer Anderson, Hyotcherl Ihee, and Keith Moffat. “Analysis of experimental time-resolved crystallographic data by singular value decomposition..” Acta Crystallographica. Section D, Biological Crystallography 60, no. Pt 5 (May 2004): 860–71. https://doi.org/10.1107/s0907444904004160.

PMID
15103131
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Schmidt, Marius, Reinhard Pahl, Vukica Srajer, Spencer Anderson, Zhong Ren, Hyotcherl Ihee, Sudarshan Rajagopal, and Keith Moffat. “Protein kinetics: structures of intermediates and reaction mechanism from time-resolved x-ray data..” Proceedings of the National Academy of Sciences of the United States of America 101, no. 14 (April 2004): 4799–4804. https://doi.org/10.1073/pnas.0305983101.

PMID
15041745
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Rajagopal, S., J. M. Key, E. B. Purcell, D. J. Boerema, and K. Moffat. “Purification and initial characterization of a putative blue light-regulated phosphodiesterase from Escherichia coli.” Photochemistry and Photobiology 80, no. 3 (January 1, 2004): 542–47. https://doi.org/10.1562/0031-8655(2004)080<0542:PAICOA>2.0.CO;2.

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Rajagopal, S., and K. Moffat. “Erratum: Crystal structure of a photoactive yellow protein from a sensor histidine kinase: Conformational variability and signal transduction (Proceedings of the National Academy of Sciences of the United States of America (February 18, 2003) 100:4 (1649-1654).” Proceedings of the National Academy of Sciences of the United States of America 100, no. 13 (June 24, 2003). https://doi.org/10.1073/pnas.1432896100.

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Schmidt, Marius, Sudarshan Rajagopal, Zhong Ren, and Keith Moffat. “Application of singular value decomposition to the analysis of time-resolved macromolecular x-ray data..” Biophysical Journal 84, no. 3 (March 2003): 2112–29. https://doi.org/10.1016/s0006-3495(03)75018-8.

PMID
12609912
Full Text

Rajagopal, Sudarshan, and Keith Moffat. “Crystal structure of a photoactive yellow protein from a sensor histidine kinase: conformational variability and signal transduction..” Proceedings of the National Academy of Sciences of the United States of America 100, no. 4 (February 2003): 1649–54. https://doi.org/10.1073/pnas.0336353100.

PMID
12563032
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