Teresa Kathleen Tarrant, MD

Associate Professor of Medicine
Campus mail 200 Trent Dr., DUMC 3874, Durham, NC 27710
Phone (919) 684-6797
Email address teresa.tarrant@duke.edu

I first became interested in clinical immunology as a medical student studying autoimmune inflammatory eye disease at the National Institutes of Health.  Since then, I have been inspired to understand what causes autoimmunity and immune deficiency disorders in order to improve the quality of life for my patients.  I see patients with multiple complex immune disorders with particular expertise in autoimmune and Rheumatoid arthritis, primary Sjogren's syndrome, and Common Variable Immunodeficiency (CVID). My research investigates immune targets that may impact either the development of immune disease or identify new therapies for patients.  The goal is to help us understand why and how immunologic diseases develop so that we may better treat them.

Education and Training

  • Immunology Postdoctoral Fellowship, Thurston Arthritis Research Center, University of North Carolina - Chapel Hill, 2004 - 2005
  • Allergy and Immunology Fellowship, Medicine, Duke University School of Medicine, 2002 - 2005
  • Rheumatology Fellowship, Medicine, Duke University School of Medicine, 2001 - 2005
  • Internal Medicine Residency, Clinical Investigator Pathway, Duke University School of Medicine, 1999 - 2001
  • M.D., University of Florida, College of Medicine, 1999

Publications

Rogers, Jennifer L., Donald S. Serafin, Roman G. Timoshchenko, and Teresa K. Tarrant. “Cellular targeting in autoimmunity.” Curr Allergy Asthma Rep 12, no. 6 (December 2012): 495–510. https://doi.org/10.1007/s11882-012-0307-y.

PMID
23054625
Full Text

Rothlein, Lisa R., Amy W. Shaheen, John P. Vavalle, Scott V. Smith, Jordan B. Renner, Nicholas J. Shaheen, and Teresa K. Tarrant. “Sclerosing mesenteritis successfully treated with a TNF antagonist.” Bmj Case Rep 2010 (December 20, 2010). https://doi.org/10.1136/bcr.07.2010.3145.

PMID
22802373
Full Text

Tarrant, Teresa K., Rishi R. Rampersad, Denise Esserman, Lisa R. Rothlein, Peng Liu, Richard T. Premont, Robert J. Lefkowitz, David M. Lee, and Dhavalkumar D. Patel. “Granulocyte chemotaxis and disease expression are differentially regulated by GRK subtype in an acute inflammatory arthritis model (K/BxN).” Clin Immunol 129, no. 1 (October 2008): 115–22. https://doi.org/10.1016/j.clim.2008.06.008.

PMID
18662895
Full Text

Graziewicz, Maria A., Teresa K. Tarrant, Brian Buckley, Jennifer Roberts, LeShara Fulton, Henrik Hansen, Henrik Ørum, Ryszard Kole, and Peter Sazani. “An endogenous TNF-alpha antagonist induced by splice-switching oligonucleotides reduces inflammation in hepatitis and arthritis mouse models.” Mol Ther 16, no. 7 (July 2008): 1316–22. https://doi.org/10.1038/mt.2008.85.

PMID
18461057
Full Text

Tarrant, T. K., R. R. Rampersad, C. G. Moore, L. R. Rothlein, R. M. Lefkowitz, D. M. Lee, and D. D. Patel. “G-Protein Receptor Kinases (grKs) Play an Important Regulatory Role in the K/BxN Serum Transfer Model of Inflammatory Arthritis.” In Journal of Allergy and Clinical Immunology, 119:S234–35. Elsevier BV, 2007. https://doi.org/10.1016/j.jaci.2006.12.288.

Full Text

Tarrant, T. K., R. R. Rampersad, R. K. Lefkowitz, D. M. Lee, and D. D. Patel. “Beta-arrestin2 and G-protein receptor kinases play an important regulatory role in the K/BxN serum transfer model of inflammatory arthritis.” In Arthritis and Rheumatism, 52:S270–S270. WILEY-BLACKWELL, 2005.

Scholars@Duke

Xu, Hui, Phyllis B. Silver, Teresa K. Tarrant, Chi-Chao Chan, and Rachel R. Caspi. “Tgf-beta inhibits activation and uveitogenicity of primary but not of fully polarized retinal antigen-specific memory-effector T cells.” Invest Ophthalmol Vis Sci 44, no. 11 (November 2003): 4805–12. https://doi.org/10.1167/iovs.02-0843.

PMID
14578402
Full Text

Tarrant, Teresa K., D Hugh Frazer, James P. Aya-Ay, and Dhavalkumar D. Patel. “B cell loss leading to remission in severe systemic lupus erythematosus.” J Rheumatol 30, no. 2 (February 2003): 412–14.

PMID
12563705
Scholars@Duke

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