Virginia Byers Kraus, MD, PhD

Professor of Medicine
Professor of Pathology
Professor in Orthopaedic Surgery
Member of Duke Molecular Physiology Institute
Affiliate of the Regeneration Next Initiative
Campus mail 300 N Duke St, Carmichael Building Room 15-205, Durham, NC 27701-2047
Phone (919) 681-6652
Email address kraus004@duke.edu

My special area of expertise is as a clinician scientist investigating osteoarthritis. Osteoarthritis is the most common form of joint disease in man and its incidence increases with age. It is a problem of increasing concern to the medical community due to the increasing longevity of the population. Trained as a molecular biologist and a Rheumatologist, I endeavor to study this disease from bedside to bench.

The work in this laboratory focuses on osteoarthritis and deals with the mechanisms of joint damage, and the discovery, validation and qualification of novel biochemical and genetic biomarkers for minimally invasive means of diagnosing disease, for predicting progression of disease, and for monitoring disease progression and response to therapy.

Education and Training

  • Fellow in Rheumatology, Medicine, Duke University, 1986 - 1989
  • Medical Resident, Medicine, Duke University, 1983 - 1986
  • Ph.D., Duke University, 1993
  • M.D., Duke University, 1982

Publications

Yuan, Jin-Qiu, Yue-Bin Lv, Hua-Shuai Chen, Xiang Gao, Zhao-Xue Yin, Wen-Tao Wang, Virginia Byers Kraus, et al. “Association Between Late-Life Blood Pressure and the Incidence of Cognitive Impairment: A Community-Based Prospective Cohort Study.” J Am Med Dir Assoc 20, no. 2 (February 2019): 177-182.e2. https://doi.org/10.1016/j.jamda.2018.05.029.

PMID
30017702
Full Text

Watt, F. E., N. Corp, S. R. Kingsbury, R. Frobell, M. Englund, D. T. Felson, M. Levesque, et al. “Towards prevention of post-traumatic osteoarthritis: report from an international expert working group on considerations for the design and conduct of interventional studies following acute knee injury.” Osteoarthritis Cartilage 27, no. 1 (January 2019): 23–33. https://doi.org/10.1016/j.joca.2018.08.001.

PMID
30125638
Full Text

Andonian, Brian J., Ching-Heng Chou, Olga R. Ilkayeva, Timothy R. Koves, Margery A. Connelly, William E. Kraus, Virginia B. Kraus, and Kim M. Huffman. “Plasma MicroRNAs in Established Rheumatoid Arthritis Relate to Adiposity and Altered Plasma and Skeletal Muscle Cytokine and Metabolic Profiles.” Front Immunol 10 (2019): 1475. https://doi.org/10.3389/fimmu.2019.01475.

PMID
31316517
Full Text

Li, Zhi-Hao, Wen-Fang Zhong, Yue-Bin Lv, Virginia Byers Kraus, Xiang Gao, Pei-Liang Chen, Qing-Mei Huang, et al. “Associations of plasma high-sensitivity C-reactive protein concentrations with all-cause and cause-specific mortality among middle-aged and elderly individuals.” Immun Ageing 16 (2019): 28. https://doi.org/10.1186/s12979-019-0168-5.

PMID
31708993
Full Text

Andonian, Brian J., David B. Bartlett, Janet L. Huebner, Leslie Willis, Andrew Hoselton, Virginia B. Kraus, William E. Kraus, and Kim M. Huffman. “Effect of high-intensity interval training on muscle remodeling in rheumatoid arthritis compared to prediabetes.” Arthritis Res Ther 20, no. 1 (December 27, 2018): 283. https://doi.org/10.1186/s13075-018-1786-6.

PMID
30587230
Full Text

Huang, Z. Y., E. Perry, J. L. Huebner, B. Katz, Y. -. J. Li, and V. B. Kraus. “Biomarkers of inflammation - LBP and TLR- predict progression of knee osteoarthritis in the DOXY clinical trial.” Osteoarthritis Cartilage 26, no. 12 (December 2018): 1658–65. https://doi.org/10.1016/j.joca.2018.08.005.

PMID
30144513
Full Text

Yuan, Jin-Qiu, Yue-Bin Lv, Virginia Byers Kraus, Xiang Gao, Zhao-Xue Yin, Hua-Shuai Chen, Jie-Si Luo, Yi Zeng, Chen Mao, and Xiaoming Shi. “Denture Use Protects Against All-Cause Mortality Associated with Tooth Loss in Older Adults,” September 29, 2018.

Scholars@Duke

Lv, Yue-Bin, Jin-Qiu Yuan, Chen Mao, Xiang Gao, Zhao-Xue Yin, Virginia Byers Kraus, Jie-Si Luo, et al. “Association of Body Mass Index With Disability in Activities of Daily Living Among Chinese Adults 80 Years of Age or Older.” Jama Netw Open 1, no. 5 (September 7, 2018): e181915. https://doi.org/10.1001/jamanetworkopen.2018.1915.

PMID
30646143
Full Text

Andonian, Brian J., Ching-Heng Chou, Virginia B. Kraus, William E. Kraus, and Kim M. Huffman. “Plasma Mir-146a-5p Associates with Beneficial Body Composition and Plasma Metabolic Profiles in Rheumatoid Arthritis.” In Arthritis & Rheumatology, Vol. 70. WILEY, 2018.

Scholars@Duke

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