Pharmacology Studies Fuel a Quest to Shed Drug Side Effects
In clinic, cardiologist Sudarshan Rajagopal, MD, PhD, has no means to cure most patients with pulmonary hypertension, not the narrowing of blood vessels in their lungs, not damage done to their hearts.
The physician-scientist can prescribe medicines that extend the lives of many patients, but the precious gains can come with unwelcome costs.
“All these drugs help open blood vessels in the lungs and help treat heart failure. But they can have horrible side effects,” Rajagopal says, including nausea, diarrhea, weight loss and other side effects.
But help may come from complex pharmacology studies that Rajagopal first encountered at Duke in the laboratory of Nobel Prize winner Robert Lefkowitz, MD.
MedicineNews Highlights from 2017
The MedicineNews blog continues to be the primary way that we feature the activities and accomplishments of the faculty, trainees and staff of the Duke Department of Medicine.
In 2017, we shared 412 news stories, including posts about faculty and trainee awards and honors, research profiles and 33 funding opportunities, as well as news and events from our training programs. Keep reading for this year's highlights.
Schmader to step down as chief of Division of Geriatrics
After 12 years as chief of the Division of Geriatrics, Kenneth Schmader, MD, has elected to step down from this leadership role on June 30, 2018, Interim Chair Joseph Rogers, MD, announced this week.
Dolor receives PCORI funding for opioid study
GIM Associate Professor, Dr. Rowena Dolor, is a recipient of a large grant from the Patient Centered Outcomes Research Institute (PCORI).
Dr. Gray's comic relief
Amateur cartoonist, Dr. Nathan Gray, shares his latest medical cartoon guide about codes status.
A search to disrupt cancer-cell trickery that makes malignant cells seem harmless
These are heady days for immunotherapy researchers, the scientists making progress unleashing the human immune system against lethal cancers.
Interventions once envisioned in laboratories are now treatments saving the lives of some patients struck by melanoma, kidney cancer, and lung cancer. Promise is rising for treatments against malignancies arising elsewhere as well.
With his new insights into how cancer cells use biochemical signaling to suppress our immune system, Brent Hanks, MD, PhD, is part of this translational momentum.
Apply for new SoM faculty development program ADVANCE-UP
The School of Medicine’s Office for Faculty is now accepting applications for the ADVANCE-UP Faculty Development Program. Applications are due Jan. 12.
SoM Financial Boot Camp
The School of Medicine invites mid-career faculty to register for its "Financial Boot Camp" series, to be held March 1, 8, and 22, 2018. Learn more and register.
DOC Holiday Celebration Photo Gallery
The Duke Outpatient Clinic celebrated the holiday season on Friday, December 8 at the lovely home of Dr. Greenblatt.