Duke Division of Nephology offers a clinic specialized for patient's with PKD and genetic kidney diseases.
The Duke Polycystic Kidney Disease (PKD) and Nephrogenetics Clinic delivers comprehensive, precision‑focused care for inherited kidney disorders by integrating advanced genetic diagnostics, expert nephrology management, and access to innovative research.
Alongside autosomal dominant and recessive polycystic kidney disease, the program evaluates and treats a broad spectrum of hereditary conditions such as
- Fabry disease
- Alport spectrum
- Autosomal dominant tubulointerstitial diseases
A major emphasis is participation in clinical trials aimed at slowing cyst progression and preserving kidney function, giving patients early access to emerging therapies. The team also provides specialized guidance on tolvaptan therapy, including eligibility assessment, monitoring, and long‑term treatment planning. This multidisciplinary model is strengthened by close collaboration with genetic counseling, hepatology, interventional radiology, pain medicine, and pediatric nephrology, ensuring that patients and families receive coordinated, lifelong support across every dimension of inherited kidney care.
Shweta Punj, MD
Nephrologist, Clinic Lead
Team Members
Matthew A. Sparks, MD
Nephrology
Ben Catanese, MD
Nephrology
Ale Tomasi, MD
Nephrology
Annabelle Chua, MD
Pediatrics Nephrology
Multidisciplinary Team
Kara Wegermann, MD
Hepatology
Muhammad Farooq Anwar, MD
Pain Medicine
Brian Shaw, MD
Surgery
Reza Navabizadeh, MD
Urology
David Johnson, MD
Interventional Radiology