Journal Club Articles and Schedule

Duke Nephrology Journal Club is held each week on Thursday morning from 8:30 to 9:30 am in the Department of Medicine Conference Room 1103 near the Duke Hospital food court. Occasionally this conference may need to be held in another location. If there is a location change, it would be listed next to the date. 

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See articles from 8/2008-6/2013 here.

See articles from 7/2013-6/2015 here

See articles from 7/2015- 12/2015 here

see articles from 2016

see articles from 2017 to June 2018

Date Speaker Articles
June 7, 2018 Pun, R. Hall

Roy-Chaudhury et al.  Primary outcomes of the Monitoring in Dialysis Study indicate that clinically significant arrhythmias are common in hemodialysis patients and related to dialytic cycle. Kidney Int. 2018 Apr;93(4):941-951.

Haugen et al. J Am Soc Nephrol. 2018 Jun;29(6):1752-1759 Incidence, Risk Factors, and Sequelae of Post-kidney Transplant Delirium

June 14, 2018 Roberts, Ortiz-Melo

Olszewski et al.Teaching Pediatric Peritoneal Dialysis Globally through Virtual Simulation.Clin J Am Soc Nephrol. 2018 Jun 7;13(6):900-906.

Tumlin et al. Outcomes in Patients with Vasodilatory Shock and Renal Replacement Therapy Treated with Intravenous Angiotensin II. Critical Care Medicine: June 2018 - Volume 46 - Issue 6 - p 949–957

June 21, 2018 Middleton, Traynor
Bansal et al. Long-term Outcomes Associated With Implantable Cardioverter Defibrillator in Adults With Chronic Kidney Disease.JAMA Intern Med. 2018 Mar 1;178(3):390-398.
Trofe-Clark et al.Results of ASERTAA, a Randomized Prospective Crossover Pharmacogenetic Study of Immediate-Release Versus Extended-Release Tacrolimus in African American Kidney Transplant Recipients.Am J Kidney Dis. 2018 Mar;71(3):315-326.
June 28, 2018 Ellis, Sanoff

Vigletti et al.Dynamic Prognostic Score to Predict Kidney Allograft Survival in Patients with Antibody-Mediated Rejection.J Am Soc Nephrol. 2018 Feb;29(2):606-619

July 5, 2018 Cameron, G. Hall

Park et al. Single-cell transcriptomics of the mouse kidney reveals potential cellular targets of kidney disease. Science. 2018 May 18;360(6390):758-763.

Website for gene and expression patterns


July 12, 2018

Smith, Gbadegesin

Ashraf et al. Mutations in six nephrosis genes delineate a pathogenic pathway amenable to treatment.Nat Commun. 2018 May 17;9(1):1960

Gunnells et al. Peripheral and renal venous plasma renin activity in hypertension.Ann Intern Med. 1969 Sep;71(3):555-75.

July 19, 2018

Mohottige, Bensimhon

Kupferman J. et al. Acute kidney injury in sugarcane workers at risk for Mesoamerican nephropathy. American Journal of Kidney Diseases. July 2018

Hua-Shan L. et al. Regional Cerebral Blood Flow in Children and Young Adults with Chronic Kidney Disease. Radiology. June 2018

July 26, 2018

Pun "Research in Progress"


August 2, 2018

Kovalik, Butterly

Shin et al. Risks and Benefits of Direct Oral Anticoagulants across the Spectrum of GFR among Incident and Prevalent Patients with Atrial Fibrillation. Clin J Am Soc Nephrol. 2018 Jul 12

Assimon et al. Failed Target Weight Achievement Associates with Short-Term Hospital Encounters among Individuals Receiving Maintenance Hemodialysis. J Am Soc Nephrol. 2018 May 23.

August 9, 2018

R. Hall, Diamantidis

Charkhchi et al. Housing and Food Insecurity, Care Access, and Health Status Among the Chronically Ill: An Analysis of the Behavioral Risk Factor Surveillance System.J Gen Intern Med. 2018 May;33(5):644-650.

August 16, 2018

Traynor, Sparks

de Weerd et al. ABO-Incompatible Kidney Transplant Outcomes: A Meta-Analysis.Clin J Am Soc Nephrol. 2018 Aug 7;13(8):1234-1243

Yong et al. MicroRNA-214-3p in the Kidney Contributes to the Development of Hypertension  ASN July 26, 2018 ahead of print July 26, 2018


August 23, 2018

Spurney, Pun

Hsien-Yen  et al Association Between Sodium-Glucose Cotransporter 2 Inhibitors and Lower Extremity Amputation Among Patients With Type 2 Diabetes JAMA Intern Med. Published online August 13, 2018

Wu et al. Enhancing natriuretic peptide signaling in adipose tissue, but not in muscle, protects against diet-induced obesity and insulin resistance. Sci Signal. 2017 Jul 25;10(489).

Bordicchia et al. Cardiac natriuretic peptides act via p38 MAPK to induce the brown fat thermogenic program in mouse and human adipocytes. J Clin Invest. 2012 Mar;122(3):1022-36.

August 30, 2018

Mohottige, Bensimhon

Harer et al. Association Between Early Caffeine Citrate Administration and Risk of Acute Kidney Injury in Preterm Neonates: Results From the AWAKEN Study. JAMA Pediatr. 2018 Jun 4;172(6):e180322

Loren et al. High prevalence of non-steroidal anti-inflammatory drug use among acute kidney injury survivors in the southern community cohort study.BMC Nephrol. 2016; 17: 189.

September 6, 2018

Ellis, Svetkey

Webster et al. Fixed Low-Dose Triple Combination Antihypertensive Medication vs Usual Care for Blood Pressure Control in Patients With Mild to Moderate Hypertension in Sri Lanka: A Randomized Clinical Trial. JAMA. 2018 Aug 14;320(6):566-579.

Newby et al. Coronary CT Angiography and 5-Year Risk of Myocardial Infarction. N Engl J Med 2018; 379:924-933

September 13, 2018

Canceled due to sever weather  

September 20, 2018

Berkoben, Morris

Rondon-Berrios et al. Urea for the Treatment of Hyponatremia.Clin J Am Soc Nephrol. 2018 Sep 4.

Pottebaum et al. Influence of pretransplant midodrine use on outcomes after
kidney transplantation. Clin Transplant. 2018 Aug 4:e13366

September 27, 2018

Scialla "Research In Progress"


October 4, 2018

Chambers, Tyson

Liao et al.  Noninvasive quantification of intrarenal allograft C4d deposition with targeted ultrasound imaging. Am J Transplant. 2018 Sep 1

McManus et al. Efficacy of self-monitored blood pressure, with or without telemonitoring, for titration of antihypertensive medication (TASMINH4): an unmasked randomised controlled trial.Lancet. 2018 Mar 10;391(10124):949-959.


October 11, 2018

Spurney, Lorch

Lin MH et al. Laminin-521 Protein Therapy for Glomerular Basement Membrane and Podocyte Abnormalities in a Model of Pierson Syndrome. J Am Soc Nephrol. 2018 May;29(5):1426-1436.

Tartof et al. Kidney Function Decline in Patients with CKD and Untreated Hepatitis C Infection. Clin J Am Soc Nephrol. 2018 Oct 8;13(10):1471-1478


October 18, 2018

Dr. Cozumel Southern Pruette M.D., M.H.S.Assistant Professor at Johns Hopkins University School of Medicine

***CME credit will be provided***

Title: Recent Trials in Pediatric CKD and Transplant Medication Adherence

***ROOM CHANGE DN 2001***

October 25, 2018



November 1, 2018

Grabner, W. Zhou

Murali et al. Role of calcium in adult onset polycystic kidney disease.Cellular Signalling
Volume 53, January 2019, 140-150

Chen et al. α-Klotho is a non-enzymatic molecular scaffold for FGF23 hormone signalling. Nature. 2018 Jan 25;553(7689):461-466. Epub 2018 Jan 17.



November 8, 2018

G. Hall, Ortiz

Haley et al. Podocyte injury elicits loss and recovery of cellular forces.Sci Adv. 2018 Jun 27;4(6):eaap8030.eCollection 2018 Jun.

Barbar et al. Timing of Renal-Replacement Therapy in Patients with Acute Kidney Injury and Sepsis.
October 11, 2018.N Engl J Med 2018; 379:1431-1442

November 15, 2018

Crowley, Lucas

Lin et al. Suppression of Endothelial-to-Mesenchymal Transition by SIRT (Sirtuin) 3 Alleviated the Development of Hypertensive Renal Injury.Hypertension. 2018 Aug;72(2):350-360. Epub 2018 Jun 18.

November 22, 2018

Thanksgiving Day

No Journal Club

November 29, 2018

Roberts, T. Yang

Faraco et al. Dietary salt promotes neurovascular and cognitive dysfunction through a gut-initiated TH17 response. Nature Neuroscience volume 21, pages 240–249 (2018). 15 January 2018.


Reese et al.Twelve-Month Outcomes After Transplant of Hepatitis C–Infected Kidneys Into Uninfected Recipients A Single-Group Trial.Annals of internal medicine 169(5) · August 2018

December 6, 2018

G. Hall "Research In Progress"


December 13, 2018

Foster "Research In Progress"  

December 20, 2018

Scialla , Tyson

Swaminathan et al. Association of Medicaid Expansion With 1-Year Mortality Among Patients With End-Stage Renal Disease.JAMA. 2018 Dec 4;320(21):2242-2250.

Kandzari et al Effect of renal denervation on blood pressure in the presence of antihypertensive drugs: 6-month efficacy and safety results from the SPYRAL HTN-ON MED proof-of-concept randomised trial.The Lancet Volume 391, ISSUE 10137, P2346-2355, June 09, 2018

December 27, 2018

Holiday Break

No Journal Club

January 3, 2019

Smith, Edmonston

Saglimbene et al. The Long-Term Impact of Renin-Angiotensin System (RAS) Inhibition on Cardiorenal Outcomes (LIRICO): A Randomized, Controlled Trial.J Am Soc Nephrol. 2018 Dec;29(12):2890-2899. Epub 2018 Nov 12. NEJM 2018 Oct;

MacDougall et al. Intravenous Iron in Patients Undergoing Maintenance Hemodialysis. The New England journal of medicine. 10.1056/nejmoa1810742

January 10, 2019

Nagaraj, Sanoff

***ROOM CHANGE DN2001***

Groopman ET AL. Diagnostic Utility of Exome Sequencing for Kidney Disease.N Engl J Med. 2018 Dec 26

Stewart DE, et al. Measuring and monitoring equity in access to deceased donor kidney transplantation.
Am J Transplant. 2018 Aug;18(8):1924-1935


January 17, 2019

Megan L. Prochaska, MD, MPH from Brigham and Woman’s Hospital

Title: “Recent Findings in Nephrolithiasis”

***ROOM CHANGE DN2001***

January 24, 2019

Cameron, Middleton

Sibbel et al. Association of Continuation of Loop Diuretics at Hemodialysis Initiation with Clinical Outcomes.Clin J Am Soc Nephrol. 2019 Jan 7;14(1):95-102. Epub 2018 Dec 19.


Wanner et al. Empagliflozin and Kidney Function Decline in Patients with Type 2 Diabetes: A Slope Analysis from the EMPA-REG OUTCOME Trial.J Am Soc Nephrol. 2018 Nov;29(11):2755-2769. Epub 2018 Oct 12.


January 31, 2019

David Ortiz, Dr. John Whited (Durham VA Associate Chief of Staff for Research

Esther et al.Effect of Lanreotide on Kidney Function in Patients With Autosomal Dominant Polycystic Kidney DiseaseThe DIPAK 1 Randomized Clinical Trial.JAMA. 2018;320(19):2010-2019

Dr. Whited will present research funding opportunities through the VA

February 7, 2019

Kovalik, Ellis

Manson et al. Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease.N Engl J Med. 2019 Jan 3;380(1):33-44.  Epub 2018 Nov 10.

Bloom et al. Cell-Free DNA and Active Rejection in Kidney Allografts.J Am Soc Nephrol. 2017 Jul;28(7):2221-2232. Epub 2017 Mar 9.


February 14, 2019


Foster, Duronville


Saglimbene et al. Fruit and Vegetable Intake and Mortality in Adults
undergoing Maintenance Hemodialysis. CJASN Feb 2019, 14 (2) 250-260

Seren et al. Consequences of cathepsin C inactivation for membrane exposure of proteinase 3, the target antigen in autoimmune vasculitis.J Biol Chem. 2018 Aug 10;293(32):12415-12428. Epub 2018 Jun 20.


February 21, 2019

Berkoben, Butterly

William et al. Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout.March 29, 2018N Engl J Med 2018; 378:1200-1210


Jaber et al.  Sodium bicarbonate therapy for patients with severe metabolic acidaemia in the intensive care unit (BICAR-ICU): a multicenter, open-label, randomized controlled, phase 3 trial.  The Lancet.  Published online June 14, 2018.

February 28, 2019

T. Souma, Musgrove

Guillaume et al. Cyclin G1 and TASCC regulate kidney epithelial cell G2-M arrest and fibrotic maladaptive repair.Sci Transl Med 11. 23 January 2019

Fenske et al. A Copeptin-Based Approach
in the Diagnosis of Diabetes Insipidus.N Engl J Med 2018;379:428-39.

March 7, 2019

Rasheeda Hall "Research In Progress"


March 14, 2019

R.Shah, H.Singh

Rovin et al. A randomized, controlled double-blind studycomparing the efficacy and safety of
dose-ranging voclosporin with placebo in
achieving remission in patients with
active lupus nephritis. Kidney International (2019) 95, 219–231.

Nelson et al. Association of Nonsteroidal Anti-inflammatory Drug Prescriptions With Kidney Disease Among Active Young and Middle-aged Adults. JAMA Network Open. 2019;2(2).

March 21, 2019

Spurney "Research In Progress"


March 28, 2019

Provenzano, Chambers

Hutchison et al. High cutoff versus high-flux haemodialysis for myeloma cast nephropathy in patients receiving bortezomib-based chemotherapy (EuLITE): a phase 2 randomised controlled trial. Lancet Haematol 2019. March 11 2019

April 4, 2019

Grabner "Research In Progress"


April 11, 2019

Lehrich, Alsubail

Assimon et al. Comparative Cardiac Safety of Selective Serotonin Reuptake Inhibitors among Individuals Receiving Maintenance Hemodialysis.JASN April 2019, 30 (4) 611-623

Mc Causland et al. Treatment of Anemia With Darbepoetin Prior to Dialysis Initiation and Clinical Outcomes: Analyses From the Trial to Reduce Cardiovascular Events With Aranesp Therapy (TREAT). Am J Kidney Dis.73(3):309-315. Published online December 19, 2018.

April 18, 2019

Nagaraj, Morris


April 25, 2019

Ting Yang "Research In Progress"


May 2, 2019

Tomokazu Souma-"Research In Progress"


May 9, 2019

Guest Speaker:

Opeyemi Olabisi, MD,PhD

Harvard Medical School


May 16, 2019

Zhou RIP


May 23, 2019

Evans, Alsubail


May 30, 2019

Crowley-"Research In Progress"


June 6, 2019

Matt Sparks "Research In Progress"


June 13, 2019

Duronville, Shah


June 20, 2019

Musah, SIngh


June 27, 2019

Svetkey RIP


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