Journal Club Articles and Schedule

Duke Nephrology Journal Club is held each week on Thursday morning from 8:30 to 9:30 am in the Department of Medicine Conference Room 1103 near the Duke Hospital food court. Occasionally this conference may need to be held in another location. If there is a location change, it would be listed next to the date. 

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See articles from 8/2008-6/2013 here.

See articles from 7/2013-6/2015 here

See articles from 7/2015- 12/2015 here

see articles from 2016

Date Speaker Articles
January 5, 2017 Middleton, Edmonston

Ku et al. Strict blood pressure control associates with decreased mortality risk by APOL1 genotype. Kidney Int., 2016

Cil et al. Small-Molecule Inhibitors of Pendrin Potentiate the Diuretic Action of Furosemide. J Am Soc Nephrol. 27(12): 3706-3714, 2016

January 12, 2017 Butterly, Kothari

Srinivas et al. Big Data, Predictive Analytics, and Quality Improvement in Kidney Transplantation: A Proof of Concept.   Am J Transplant. Nov. 2016 [Epub ahead of print]

Dahan et al. Rituximab for Severe Membranous Nephropathy: A 6-Month Trial with Extended Follow-Up. J Am Soc Nephrol. 28(1):348-358, 2017

January 19, 2017 Cameron, Mohottige

Schroeder et al. Predicting 5-Year Risk of RRT in Stage 3 or 4 CKD: Development and External Validation. Clin J Am Soc Nephrol. 12(1):87-94, 2017

Patzer et al. A Randomized Trial to Reduce Disparities in Referral for Transplant Evaluation. J Am Soc Nephrol, 2016 [Epub ahead of print]

January 26, 2017 Svetkey Research in Progress
February 2, 2017 Ortiz-Melo, Berkoben

Block et al. Effect of Etelcalcetide vs Cinacalcet on Serum Parathyroid Hormone in Patients Receiving Hemodialysis with Secondary Hyperparathyroidism A Randomized Clinical Trial. JAMA, Jan 10;317(2):156-164, 2017

Barrera-Chimal et al. Benefit of Mineralocorticoid Receptor Antagonism in AKI: Role of Vascular Smooth Muscle Rac1, J Am Soc Nephrol, 2017 [Epub ahead of print]

February 9, 2017 Roberts, G. Hall

Braun et al. Mutations in nuclear pore genes NUP93, NUP205 and XPO5 cause steroid-resistant nephrotic syndrome. Nature Genetics.Nat Genet. 48(4):457-65, 2016

Grinyó et al. Safety and Efficacy Outcomes 3 Years After Switching to Belatacept From a Calcineurin Inhibitor in Kidney Transplant Recipients: Results From a Phase 2 Randomized Trial. Am J Kidney Dis., 2016 [Epub ahead of print]

February 16, 2017 Stanifer, Chua

Heerspink et al. Canagliflozin Slows Progression of Renal Function Decline Independently of Glycemic Effects. J Am Soc Nephrol. 28(1):368-375, 2017

Rebholz et al. Diet Soda Consumption and Risk of Incident End Stage Renal Disease. Clin J Am Soc Nephrol. 12(1):79-86, 2017

February 23, 2017 Spurney Research in Progress
March 2, 2017 Olivo, Traynor

Locke et al. Obesity increases the risk of end-stage renal disease among living kidney donors. Kidney Int. 91(3):699-703, 2017

Xie et al. Long-term kidney outcomes among users of proton pump inhibitors without intervening acute kidney injury. Kidney Int. 2017, [Epub ahead of print]

March 9, 2017 Smith, Singh

Shah et al. Warfarin Use and the Risk for Stroke and Bleeding Patients with Atrial Fibrillation Undergoing Dialysis. Circulation. 129(11):1196-203, 2014

March 16, 2017 R. Hall Research in Progress
March 23, 2017 Karl Tryggvason (Duke-NUS) Title of Talk: Genetics of Diabetic Nephropathy
March 30, 2017 Scialla, Lehrich

Carlos et al. Colon Cancer Screening among Patients Receiving Dialysis in the United States: Are We Choosing Wiseley? J Am Soc Nephrol. 2017

Nadkarni et al. Apolipoprotein L1 Variants and Blood Pressure Traits in African Americans. Journal of American College of Cardiology. 69(12): 1564-1574, 2017

April 6, 2017

Tomokazu Souma (Northwestern)

Title of Talk: Dysregulation of Oxygen Homeostasis and Kidney Diseases
April 13, 2017 Makar, Morris

Mathur et al. Patterns of Care and Outcomes in Cardiovascular Disease After Kidney Transplantation in the United States. Transplant Direct. 16;3(2), 2017

Mavrakanas et al. Apixaban Pharmacokinetics at Steady State in Hemodialysis Patients. J Am Soc Nephrol. 2017,  [Epub ahead of print]

April 20, 2017 Sparks, Bensimhon

Beckerman et al. Transgentic expression in human APOL1 risk variants in podocytes induces kidney disease in mice. Nat Med. 23(4):429-438, 2017

Jones et al. Gene-Specific DNA Methylation Changes Predict Remission in Patients with ANCA-Associated Vasculitis. J Am Soc Nephrol. 28(4):1175-1187, 2017

April 27, 2017

Christina Wyatt (Icahn School of Medicine at Mount Sinai)

Title of Talk: The Kidney & HIV: Implications for Treatment, Prevention, and Cure
May 4, 2017 Gbadegesin, Edmonston

Lopez-Rivera et al. Genetic Drivers of Kidney Defects in the DiGeorge Syndrome. The New England Journal of Medicine. 23;376(8):742-754, 2017

Brown et al. The Survival Benefit of “Fistula First, Catheter Last” in Hemodialysis Is Primarily Due to Patient Factors. 28(2):645-652, 2017

May 11, 2017 Foster, Kothari

Danquah et al. Nanobodies that block gating of the P2X7 ion channel ameliorate inflammation. 23;8(366):366ra162, 2016

Meuleman et al. Sodium Restriction in Patients With CKD: A Randomized ControlledTrial of Self-management Support. Am J Kidney Dis. 69(5):576-586, 2017    

May 18, 2017 Crowley Research in Progress
May 25, 2017 Tsai, Mohottige

Choi et al. Assessment of Tocilizumab (Anti-Interleukin-6 Receptor Monoclonal) as a Potential Treatment for Chronic Antibody-Mediated Rejection and Transplant Glomerulopathy in HLA-Sensitized Renal Allograft Recipients. Am Journal of Transplantation. 2017 [Epub ahead of print]

Cervantes et al. The Illness Experience of Undocumented Immigrants with End-stage Renal Disease. JAMA Intern Med. 177(4):529-535, 2017

June 1, 2017 Sparks Research in Progress
June 8, 2017 Pun, Evans

Lai et al. High Hepatitis C Viral Load and Genotype 2 are Strong Predictors of Chronic Kidney Disease. Kidney International. 2017, [Epub ahead of print]

Jardine et al. A Trial of Extending Hemodialysis Hours and Quality of Life. J Am Soc Nephrol. 28(6):1898-1911, 2017

June 15, 2017

Ellis, Sanoff

Ashby et al. A Kidney Graft Survival Calculator that Accounts for Mismatches in Age, Sex, HLA, and Body Size. Clin J Am Soc Nephrol. 2017 [Epub ahead of print]

Manfredini et al. Exercise in Patients on Dialysis: A Multicenter, Randomized Clinical Trial. J Am Soc Nephrol. 28(4):1259-1268, 2017

June 22, 2017 Bensimhon, Singh

Fishbane et al. Effects of Ferric Citrate in Patients with Nondialysis-Dependent CKD and Iron Deficiency Anemia. J Am Soc Nephrol. 28(6):1851-1858, 2017

van den Brand et al. Safety of Rituximab Compared with Steroids and Cyclophosphamide for Idiopathic Membranous Nephropathy. J Am Soc Neprol. 2017 [Epub ahead of print]

July 6, 2017 Stanifer, Butterly 

Zoccali et al. Chronic Fluid Overload and Mortality in ESRD. J Am Soc Nephrol. 2017 [Epub ahead of print]

Bansal et al. Blood Pressure and Risk of Cardiovascular Events in Patients on Chronic Hemodialysis. THe CRIC Study (Chronic Renal Insuffiency Cohort). Hypertension. 2017, [Epub ahead of print]

July 13, 2017 Cameron Barnett et al. Los Angeles Safety-Net Program eConsult System Was Rapidly Adopted and Decreased Wait Times to See Specialists. Health Affairs. 36(3):492-499, 2017
July 20, 2017 Duronville, Svetkey

Williamson et al. Intensive vs. Standard Blood Pressure Control and Cardiovascular Disease Outcomes in Adults Aged ≥75 Years: A Randomized Clinical Trial. JAMA. 315(24):2673-82, 2016.

Fellström et al. Targeted-release budesonide versus placebo in patients with IgA nephropathy (NEFIGAN): a double-blind, randomised, placedo-controlled phase 2b trial. May 27;389(10084):2117-2127, 2017

July 27, 2017 

Nephrology Morning Conference: Rajiv Agarwal (Indiana University)

***DHN, 2001***    (8:30-9:30am)

 
August 3, 2017 Morris, Kovalik

Formica et al. Simultaneous Liver-Kidney Allocation Policy: A Proposal to Optimize Appropriate Utilization of Scarce Resources. 16(3):758-66, 2016

Park et al. Midterm eGFR and Adverse Pregnancy Outcomes: The Clinical Significance of Gestational Hyperfiltration. 7;12(7):1048-1056, 2017

August 10, 2017 Edmonston, Tyson

Raphael et al. Urine Ammonium Predicts Clinical Outcomes in Hypertensive Kidney Disease. Clinical Epidemiology. 28(8):2483-2490, 2017

Molnar et al. Pre-ESRD Depression and Post-ESRD Mortality in Patients with Advanced CKD Transitioning to Dialysis. Clin J Am Soc. 2017 [Epub ahead of print]Nephrol. 

August 17, 2017 Gbadegesin Research in Progress
August 24, 2017 Kothari, Middleton

Jordan et al. IgG Endopeptidase in Highly Sensitized Patients Undergoing Transplantation. NEJM. 3;377(5):442-453, 2017

Neal et al. Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes. NEJM. 17;377(7):644-657, 2017

August 31, 2017 Scialla Research in Progress
September 7, 2017 Lehrich, Wolf

Ishida et al. Marijuana Use and Estimated Glomerular Filtration Rates in Young Adults. CJASN. 2017 [Epub ahead of print]

Mann et al. Liraglutide and Renal Outcomes in Type 2 Diabetes. NEJM. 377(9):839-848, 2017

September 14, 2017 G. Hall, Smith

Suleiman et al. Injury-induced actin cytoskeleton reorganization in podocytes revealed by super-resolution microscopy. JCI Insight. 17;2(16), 2017 [Epub ahead of print]

Cheung et al. Effects of Intensive BP Control in CKD. JASN. 28(9):2812-2823, 2017

September 21, 2017 Foster Research in Progress
September 28, 2017 Spurney, Chambers

Massie et al. Quantifying Postdonation Risk of ESRD in Living Kidney Donors. JASN. 28(9):2749-2755, 2017

October 5, 2017 Gurley, Chua

Iyasere et al. Cognitive function and advanced kidney disease: longitudinal trends and impact on decision-making. Clinical Kidney Journal. 10(1):89-94, 2017

Ware et al. Phenotypic and pharmacogenic evaluation of patients with thiazide-induced hyponatremia. J Clin Invest. 127(9):3367-3374, 2017  

 

 

October 12, 2017 Evans, Bensimhon

Tesar et al. Bosutinib versus Placebo for Automated Dominant Polycystic Kidney Disease. J Am Soc Nephrol 28, 2017 [Epub ahead of print]

Kamei et al. Long-term outcome of childhood-onset complicated nephrotic syndrome after a multicenter, double-blind, randomized, placebo-controlled trial of rituximab. Pediatr Nephrol. 2017 [Epub ahead of print]

October 19, 2017  Gregory Hundemer, MD, MPH                 (Brigham and Women’s Hospital)  
October 26, 2017 Makar, Ellis

Charytan et al. Coronary flow reserve is predictive of the risk of cardiovascular death regardless of chronic kidney disease stage. Kidney Int. (17)30571-9, 2017

Julian et al. Effect of Replacing Race with Apolipoprotein L1 Genotype in Calculation of Kidney Donor Risk Index.  American Journal of Transplantation, 17(6):1540-1548. 2017

     
November 9, 2017 Crowley, Berkoben

Sing et al. Evidence for Prophypertensive, Proinflammatory Effect of Interleukin-10 During Chronic High Salt Intake in the Condition of Elevated Angiotensin II Level. Hypertension. Oct;70(4):839-845, 2017

Bushinsky et al. Randomized, Controlled Trial of TRC101 to increase Serum Bicarbonate in Patients with CKD. Clin J Am Soc Nephrol. 2017

November 16, 2017 Pun Research in Progress
November 30, 2017 Ortiz-Melo, Alsubail

Weisbord et al. Outcomes after Angiography with Sodium Bicarbonate and Acetylcysteine. NEJM. 2017 [Epub ahead of print]

Torres et al. Tolvaptan in Later-Stage Autosomal Dominant Plycystic Kdney Disease. 377(20):1930-1942. 2017

December 7, 2017 Roberts, Seay

Duineveld et al. Living Donor Kidney Transplantation in Atypical Hemolytic Uremic Syndrome: A Case Series. Am J Kidney Dis. 70(6):770-777. 2017

Levi et al. Midterm Outcomes of 12 Renal Transplant Recipients Treated with Eculizumab to Prevent Atypical Hemolytic Syndrome Recurrence. Transplantation. 101(12):2924-2930. 2017

Bridoux et al. Effect of High Cutoff Hemodialysis  vs Conventional Hemodialysis on Hemodialysis Independence Among Patients with Myeloma Cast Nephropathy: A Randomized Trial. 318(21):2099-2110. 2017

 

December 14, 2017 G. Hall Research in Progress
December 21, 2017 Sanoff, Traynor

Adams et al.  Belatacept Combined with Transient Callcineurin Inhibitor Therapy Prevents Rejection and Promotes Improved Long-Term Renal Allograft Function. (11):2922-2936. 2017

Bowring et al. Turn down for what? Patient outcomes associated with declining increased infectious risk kidneys. Am J Transplant. 2017;00:1–8.

January 11, 2018 Shah, Grabner

Lalau et al. Metformin Treatment in Patients With Type 2 Diabetes and Chronic Kidney Disease Stages 3A, 3B, or 4. Aliment Pharmacol Ther. (5):537-44. 2004 

Han et al. Cardiovascular Effects of Renal Distal Tubule Deletion of the FGF Receptor 1 Gene. JASN January 2018 vol. 29 no. 169-80

January 18, 2018 Svetkey Research in Progress (Due to inclement weather, this talk has been rescheduled for 2/15)
January 25, 2018 Musgrove, Lehrich

Block et al. Effect of Tenapanor on Serum Phosphate in Patients Receiving Hemodialysis. J Am Soc Nephrol. 2017 Jun;28(6):1933-1942. doi: 10.1681/ASN.2016080855. Epub 2017 Feb 3.

Eisenga et al. C-Terminal Fibroblast Growth Factor 23, Iron Deficiency, and Mortality in Renal Transplant Recipients.J Am Soc Nephrol. 2017 Dec;28(12):3639-3646. doi: 10.1681/ASN.2016121350. Epub 2017 Aug 3.

February 1, 2018 Morris, Stanifer

Provenzano et al. Oral Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor Roxadustat (FG-4592) for the Treatment of Anemia in Patients with CKD. Clin J Am Soc Nephrol. 2016 Jun 6;11(6):982-91. doi: 10.2215/CJN.06890615. Epub 2016 Apr 19

Wang et al. Serum metabolome biomarkers associate low-level environmental perfluorinated compound exposure with oxidative /nitrosative stress in humans. Environ Pollut. 2017 Oct;229:168-176. doi: 10.1016/j.envpol.2017.04.086. Epub 2017 Jun 6.

February 8, 2018 Kothari Project in Progress
February 15, 2018 Svetkey Research in Progress
February 22, 2018 Spurney Research in Progress
March 1, 2018 Seay, Roberts  
March 8, 2018 Smith, Makar  
March 15, 2018 Middleton, Cameron  
March 22, 2018 R. Hall Research in Progress
March 29, 2018 Shah, Diamantidis  
April 5, 2018 Ortiz-Melo, Musgrove  
April 12, 2018 Gbadegesin, Edmonston  
April 19, 2018 Diamantidis Research in Progress
April 26, 2018 Nagaraj, Foster  
May 3, 2018 Chambers, Berkoben  
May 10, 2018 Crowley Research in Progress
May 17, 2018 Chua, Duronville  
May 24, 2018 Sparks Research in Progress
May 31, 2018 Bensimhon, Evans  
June 7, 2018 Pun, Kovalik  
June 14, 2018 Sanoff, R. Hall  
June 21, 2018 Lehrich, Traynor  
June 28, 2018 Ellis, Roberts  

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