Active NIH grants

Medicine faculty and trainees receive significant research and career-development support from the National Institutes of Health. The tables below list faculty with current grants from R and K mechanisms.

Our faculty also have 47 P grants and 93 U grants.

These tables were last updated January 2019.

Research Programs

Investigator Division Project Grant
Christopher Kontos Cardiology Skeletal Muscle and Vascular Remodeling in Peripheral Artery Disease R01
Deepak Voora Cardiology Development Of Prognostic Platelet RNA Biomarkers To Tailor Antiplatelet Therapy R01
Eric Velazquez Cardiology STICHES R01
Francis Miller Cardiology Integrated MiRNA regulation of Nox4 and cellular redox in vascular disease R01
Gerald S. Bloomfield Cardiology Pathways to cardiovascular disease prevention and impact of specialty referral in under-represented racial/ethnic minorities with HIV R01

Howard A. Rockman

Cardiology

Mechanisms of Maladaptation in Heart Failure

R01
Jonathan A. Stiber Cardiology Role of Drebrin in Atherosclerosis R01
Michael D. Gunn Cardiology Development of anti-Salmonella Single-chain Abs as serum diagnostics R33
Paul B. Rosenberg Cardiology STIM1 and metabolic flexibility R01
Ravi Karra Cardiology Angiogenic Approaches to Stimulate Heart Regeneration R03
Robert J. Lefkowitz Cardiology Molecular Regulation of Cardiovascular 7 TM Receptors R01

Sudarshan Rajagopal

Cardiology

Biasing CXCR3 Signaling to Modulate the Inflammatory Response

R01

Sudarshan Rajagopal

Cardiology

Beta-Arrestin Regulation of VEGFR3 Signaling in Pulmonary Hypertension

R03
Mary E. Klotman Chair's Office

The Genitourinary Tract as a compartment and reservoir for HIV

R01
Wilton B. Williams DHVI Neonatal Immunity to novel TF SHIVs R01
David D'Alessio Endocrinology INCRETIN ACTION IN PHYSIOLOGY AND DIABETES R01
Deborah Muoio Endocrinology Role of Carnitine Acetyltransferase in Mitochondrial and Metabolic Function R01
Jenny Tong Endocrinology The Role of Ghrelin to Regulate Insulin Secretion in Health and Diabetes R01
Matthew D. Hirschey Endocrinology Post-Translational and Epigenetic Control of Branched-Chain Amino Acid Metabolism R01
Matthew D. Hirschey Endocrinology Novel SIRT5 Enzymatic Activity Regulates Cellular Mechanisms of Aging and Disease R01
Anna Mae Diehl Gastroenterology Hedgehog Signaling and Adult Liver Regeneration R01
Anna Mae Diehl Gastroenterology TNF Alpha and Recovery from Alchoholic Liver Injury R37
Diego Bohorquez Gastroenterology Tasting Gut Bacteria R03
Katherine Garman Gastroenterology The role of gastrin in esophageal submucosal gland acinar ductal metaplasia R01
Rodger A. Liddle Gastroenterology Pathogenic Mechanisms of Pancreatitis R01
Rodger A. Liddle Gastroenterology The role of gut endocrine cells in Parkinson's Disease R01
Wei Chen Gastroenterology Inhibition of Wnt/B-Catenin Signaling in Colorectal Cancer Therapy R01

Keisha Bentley-Edwards

General Internal Medicine

Religion, Spirituality and CVD Risks: A Focus on African Americans

R01

Rowena J. Dolor General Internal Medicine A Community-based Assessment of Skin Care, Allergies and Eczema (CASCADE) R01
Susanne B. Haga General Internal Medicine Pharmacogenetic Testing: Challenges of Clinical Integration R01
Susanne B. Haga General Internal Medicine Summer Scholars Program in Genome Sciences and Medicine R25
Christopher B. Bowling  Geriatrics Sustained blood pressure control and progression of multimorbidity R01
Heather E. Whitson Geriatrics Cognitive Changes and Brain Connectivity in Age-Related Macular Degeneration R01
Nelson J. Chao Hematologic Malignancies and Cellular Therapy

Patient-centered home-based hematopoietic stem cell transplantation

R01
Sandeep Dave Hematologic Malignancies and Cellular Therapy

Defining the Functional Role of Mutations in Diffuse Large B cell Lymphoma

R01
Sandeep Dave Hematologic Malignancies and Cellular Therapy

Understanding the Context-Dependent Roles of Mutations in Lymphoma

R01
Stefanie Sarantopoulos Hematologic Malignancies and Cellular Therapy

Pathological B Cells: Novel Strategies to Prevent and Treat Chronic GVHD

R01

Yiping Yang

Hematologic Malignancies and Cellular Therapy

T memory stem cells in cancer

R01

Yiping Yang

Hematologic Malignancies and Cellular Therapy

Novel Strategies for Cancer Immunotherapy in Stem Cell Transplant

R01
Yubin Kang  Hematologic Malignancies and Cellular Therapy

Targeting sphingosine kinase 2 for the treatment of multiple myeloma

R01
Yubin Kang  Hematologic Malignancies and Cellular Therapy

Effects of PPAR agonists on response to immunomodulatory agents in patients with multiple myeloma

R21
J. Brice Weinberg Hematology Nitric Oxide and Microvascular Dysfunction in Severe Malaria R01
Rahima Zennadi Hematology Role of RBC Reactive Oxygen Species and Their Vicious Cycle in Sickle Vasculopathy R01​
Andrew Alspaugh Infectious Diseases Coordinated Regulation of Virulence Genes in C. neoformans R01
Deverick J. Anderson Infectious Diseases Prevention of Surgical Site Infection using Statistical Process Control Charts R01
Feng Gao Infectious Diseases Dissection of polyreactivity and neutralization activity of HIV-1 Abs R01
Greg Gray Infectious Diseases Swine Influenza Virus Transmission in Confined Animal Feeding Operations, China R01
John Perfect Infectious Diseases Evolution of Cryptococcus neoformans Strains from Patients with HIV/AIDS R01
John Perfect Infectious Diseases Pathobiology of C. neoformans in the Central Nervous System R01

Micah T. McClain

Infectious Diseases

Host-derived biomarker signatures to differentiate acute viral, bacterial, and fungal infection

R21
Steve Taylor Infectious Diseases Impact of Sickle-Trait on Transcriptional Regulation in P. Falciparum Parasites R21
Steve Taylor  Infectious Diseases

Malaria chemoprevention in children with sickle cell anemia in Western Kenya

R01
Susanna Naggie Infectious Diseases Identification of Novel Bioactive Lipid Metabolites for Predicting Liver-related Outcomes in Persons Co-Infected with HIV and HCV R01
Vance G. Fowler Jr. Infectious Diseases Host Susceptibility to S. aureus R01
Vivian H. Chu Infectious Diseases Optimizing treatment for E. faecalis infective endocarditis: ampicillin plus ceftriaxone versus ampicillin plus gentamicin R34
Wendy A. Prudhomme - O'Meara Infectious Diseases Innovative partnership to target antimalarial subsidies in the retail sector R01

Wendy A. Prudhomme - O'Meara
 

Infectious Diseases Malaria diagnostic testing and conditional subsidies to target ACTs in the retail sector: the TESTsmART trial R01
Wendy A. Prudhomme - O'Meara Infectious Diseases Spatial Scales of Plasmodium Falciparum Generations; Implications for Elimination R21

Wendy A. Prudhomme - O'Meara
 

Infectious Diseases Quantifying parasite importation in an epidemic-prone zone of northern Kenya R21
Kevin C. Oeffinger Medical Oncology EMPOWER Study: Promoting BC Screening in Women Who Survived Childhood Cancer R01

Steven Patierno

Medical Oncology

Race-related alternative splicing: novel targets in prostate cancer

R01

Syed Y. Zafar

Medical Oncology

PAPNavigator STTR (Fast-Track)

R42
Allison E. Ashley-Koch Nephrology Transcriptomic, therapeutic and genetic investigations of sickle cell nephropathy R01
Christina M. Wyatt Nephrology Impact of early antiretroviral therapy on kidney disease outcomes R01
Julia Scialla Nephrology Integrated Mineral Metabolism Treatment Strategies in Patients on Dialysis R01
Mary H. Foster Nephrology

Gene-Environment Collaboration in Autoimmune Disease

R01
Myles Wolf Nephrology

Role of FGF23 in Mineral Metabolism Across the Spectrum of Chronic Kidney Disease

R01

Myles Wolf Nephrology FGF23 and Cardiovascular Disease in CKD (CRIC) R01
Patrick H. Pun Nephrology Evaluating and Improving Cardiac Arrest Resuscitation Efforts in Hemodialysis Clinics R03
Rasheeda K. Hall Nephrology Improving Quality of Life Measurement in Older Dialysis Patients R03
Steven D. Crowley Nephrology Role of Th1 Immune Responses in the Pathogenesis of Hypertensive Kidney Injury R01
Steven D. Crowley Nephrology Role of Dendritic Cell-mediated T Cell Activation in Salt-sensitive Hypertension R01
Thomas M. Coffman Nephrology Paracrine Control of Blood Pressure by Renal Intercalated Cells R01
Christopher Cox Pulmonary Needs and triggers:  improving intensive care unit-based palliative care delivery R21
Claude A. Piantadosi Pulmonary

Mitochondrial quality control and alveolar damage resolution after acute lung injury 

R01
David M. Murdoch Pulmonary A Systems Biology Approach to HIV-associated Neurocognitive Impairment: Role of Drug Abuse and Neuroinflammation R01
David M. Murdoch Pulmonary Magnetically directed single cell transcriptome analysis in HIV latency R01
Harvey Marshall Pulmonary S-nitrosothiols, NF-KappaB and Inflammation in Acute Lung Injury R01

Jennifer L. Ingram

Pulmonary

Mechanisms that Direct Airway Remodeling in Obese Asthma

R01

Robert M. Tighe

Pulmonary

CXCL10/CXCR3 regulation of ozone-induced epithelial permeability

R01
Donghai Wang Rheumatology and Immunology Censoring Inflammation by Protein Geranylgeranylation R01
Donghai Wang Rheumatology and Immunology Innate Immune Inhibition of the Mevalonate Pathway Impairs Neurodevelopment during ZIKV Infection R21
Virginia B. Kraus Rheumatology and Immunology Epigenetic Mechanisms Promoting Longevity R01

Virginia B. Kraus

Rheumatology and Immunology

Qualification of Prognostic and Diagnostic Biomarkers of Knee Osteoarthritis

R01

Virginia B. Kraus

Rheumatology and Immunology

Extracellular Vesicles and Their Role in Hallmarks of Aging

R56

Career Development

Investigator Division Project Grant
Ann M. Navar  Cardiology Preventing Cardiovascular Disease through Improved Risk Prediction and Communication K01
Dennis M. Abraham Cardiology TREK-1 in fibroblast differentiation and cardiac fibrosis development K08

James W. Wisler

Cardiology

Mechanistic studies of Mas receptor activation and its role in aortic aneurysm formation

K08

Robert W. McGarrah III Cardiology The Branched Chain Ketoacid Dehydrogenase Kinase-Phosphatase System as a New Regulatory Node in Mycocardial Fuel Section K08
Richard H. Lee Endocrinology Metabolomic & Radiographic Markers of Fracture Risk Among Older Adults with Diabetes K23
Diego Bohorquez Gastroenterology Gut-Brain Neurocircuit Modulating Eating Behavior K01
Clarissa J. Diamantidis General Internal Medicine Is there a digital divide in Chronic Kidney Disease (CKD)? K23
Nrupen Bhavsar General Internal Medicine Addressing Bias from Missing Data in EHR Based Studies of CVD K01
Cathleen S. Colon-Emeric Geriatrics Mentoring Intervention Development in Fall and Fracture Prevention K24
Phuong L. Doan Hematologic Malignancies and Cellular Therapy

Role of ErbB receptor signaling in regulating normal and leukemic stem cell fate 

K08
Grace M. Lee Hematology Biological Significance of Protamine/Heparin Antibodies K08
James White Hematology The AMPK/ULK1/p27Kip1 axis regulates autophagy and cell survival in aged satellite cells K01
Marilyn J. Telen Hematology Duke-UNC Clinical Hematology and Transfusion Research Career Development Program K12
L. Gayani Tillekeratne Infectious Diseases Novel Diagnostics to Improve Antimicrobial Stewardship for Acute Respiratory Tract Infections in Resource-Limited Settings K23
Matthew P. Rubach Infectious Diseases Viral Zoonoses and Severe Febrile Illness in Northern Tanzania K23
Rebekah W. Moehring Infectious Diseases Defining Measures of Impact for Antimicrobial Stewardship Programs in Community Hospitals K08
Vance G. Fowler Jr. Infectious Diseases Mentoring Patient Oriented Research in Antibiotic-Resistant Bacteria K24
Arif H. Kamal Medical Oncology Which palliative care quality measures improve patient-centered outcomes? K08
Brent A. Hanks Medical Oncology Melanoma-mediated Dendritic Cell Tolerization and Immune Evasion K08

Gentzon Hall

Nephrology

The Role of Interleukin-15 Receptor-alpha Variants in the Pathogenesis of FSGS

K08

Rasheeda K. Hall Nephrology Deprescribing for Older Dialysis Patients K76
Bryan D. Kraft Pulmonary Role of S-nitrosothiols in Akt1 signaling and pneumonia resolution K08
Christina E. Barkauskas Pulmonary The role of Pdgfra+ fibroblasts in lung fibrosis and alveolar homeostasis K08
Jamie L. Todd Pulmonary Immune Profiles to Better Understand Chronic Allograft Dysfunction and Successful Long-term Clinical Outcomes after Human Lung Transplantation K23
Yen Rei Yu Pulmonary Role of Resident Monocytes in the Pathogenesis of Pulmonary Arterial Hypertension K08