Duke GI is a leader in translating fundamental discoveries in the laboratory into state-of-the-art care
Areas of Active investigation include:
- MASLD/MASH: Anna Mae Diehl, MD, Cynthia Moylan, MD
- Liver Fibrogenesis and Regeneration: Anna Mae Diehl, MD, Cynthia Moylan, MD
- Metabolic Liver Disease: Dimi Bissig, MD, PhD
- Liver-related genetics, epigenetics, single cell RNA-sequencing: Dimi Bissig, MD, PhD, Anna Mae Diehl, MD, Cynthia Moylan, MD
- Gut-liver: Anna Mae Diehl, MD
- Gut-brain neuroscience/signaling: Diego Bohorquez, PhD, Rodger Liddle, MD
- GI hormone physiology: Rodger Liddle, MD, Katherine Garman, MD
- Pancreas: Rodger Liddle, MD
- Esophageal Diseases and Swallowing Disorders: David Leiman, MD, Amit Patel, MD, Katherine Garman, MD
- GI tract tissue injury, repair and carcinogenesis: Katherine Garman, MD
- GI and liver cancers: Anna Mae Diehl, MD (liver), Katherine Garman, MD (esophagea, gastrin), Jatin Roper, MD (colorectal), Cynthia Moylan, MD (liver)
- Microbiome: John Rawls, PhD, Lawrence David, Phd
- Nutrition and Metabolism: John Rawls, PhD
- Liver Immunology: Anna Mae Diehl, MD, Gianna Hammer, PhD
- Inflammatory Bowel Disease and Gut Immunology: Michel Bagnat, PhD, Maria Ciofani, PhD , Katherine Garman, MD, Gianna Hammer, PhD
Duke GI researchers are also experts in basic and translation investigation study design and methodologies such as:
- In vitro approaches to complex human diseases (organoids / 3D culture): Anna Mae Diehl, MD, Katherine Garman, MD, Rodger Liddle, MD, Jatin Roper, MD
- Genomic Approaches and Personalized Medicine: Cynthia Moylan, MD, Anna Mae Diehl, MD, John Rawls, PhD, Maria Ciofani, PhD, Katherine Garman, MD
- Genome engineering and experimental therapeutics (cell therapy, CRISPR): Dimi Bissig, MD, PhD, Jatin Roper, MD
Listen as Rodger Liddle, MD, and Diego Bohorquez, PhD narrate the below video on their research on appetite control. Read the paper in PLOS ONE.