Our basic and translational research in liver cancer currently concentrates on environmental exposures as well as novel mechanisms of cancer risk.

We are interested in how certain environmental exposures affect epigenetic mechanisms that increase liver cancer risk in certain populations as well as genomic splice variants that may also lead to racial and ethnic disparities in liver cancer risk. Understanding these mechanisms is important as they have the potential to improve early detection, and to inform new treatments. We collaborate and work closely with several groups outside of GI on this work including the Duke Cancer Institute, the bioinformatics group at Duke the Duke Pathology Departmentand NC State University.

Faculty:  Cynthia Moylan, MD