The Duke Center for Precision Medicine is committed to providing educational resources for providers. Specifically, there are resources available for Hereditary Cancer Predisposition Testing and Tumor Profiling and Targeted Treatment. Additional resources are outlined below.
- Precision Medicine Academy: A suite of online courses on different topics related to precision medicine by Duke Adjunct Professor, Jeanette McCarthy
- CDC Office of Public Health Genomics: Provides timely and credible information for the effective and responsible translation of genomics research into population health benefits
- The Jackson Laboratory (JAX): The Jackson Laboratory is an independent, nonprofit biomedical research organization. Their mission is to discover precise genomic solutions for disease and empower the global biomedical community in our shared quest to improve human health. The Clinical and Continuing Education Program (CCEP) at The Jackson Laboratory helps prepare clinicians for precision medicine by training them to apply relevant, clinically actionable genomics at the point of care
- Genetic and Genomic Competency Center (G2C2): An online repository of genomics educational materials, including peer-reviewed collections for genetic counselors, nurses, pharmacists, physician assistants, and physicians
- Regulation of Genetic Tests: The National Human Genome Research Institute has developed a primer on the regulation of genetic tests
- Genomic and Precision Medicine on Coursera: Free online 7-week courses aims to educate the health care workforce in the field of genomic and precision medicine
- National Human Genome Research Institute (NHGRI) Health Professionals: Resources provide reliable, up-to-date information about genomics competencies, patient care, and our partnership and outreach activities.
- Genetics Education for Healthcare: Provides tools and information to support learners, educators and clinicians in the delivery of genomic medicine. Excellent primers on genomic concepts, lesson plans, as well as practical information for health care providers
- ACCE Framework: The CDC’s Office of Public Health Genomics (OPHG) developed a framework for considering the validity and utility of emerging genetic tests, which has been widely adopted by the biomedical community. The ACCE model encompasses four areas: analytic validity (How accurately and reliably the test measures the genotype of interest), clinical validity (How consistently and accurately the test detects or predicts the intermediate or final outcomes of interest), clinical utility (How likely the test is to significantly improve patient outcomes) and ethical, legal, social implications that may arise in the context of using the test. Analytic validity is usually in the purview of the testing laboratory that ensures accurate detection and reporting of the assay results. The bigger challenge is establishing clinical validity and utility, a process that requires data curation from the primary scientific literature.
- Building the Evidence for Genomic Tests: Several groups curate, evaluate and synthesize evidence from published research supporting clinical validity and utility of tests to guide clinicians:
- CDC Office of Public Health Genomics: Guidelines, Policies and Recommendations in Genomics: The CDC compiles an updated list of guidelines, policies and recommendations on genomic research and practice, as provided by professional organizations, federal advisory groups, expert panels and policy groups.
- Clinical Pharmacogenetics Implementation Consortium (CPIC): Provides dosing guidelines for patients who have undergone pharmacogenomic testing for specific drugs.
- GeneReviews: GeneReviews are expert-authored, peer-reviewed disease descriptions presented in a standardized format and focused on clinically relevant and medically actionable information on the diagnosis, management, and genetic counseling of patients and families with specific inherited conditions.
- Agency for Healthcare Research and Quality (AHRQ): Public resource for evidence-based clinical practice guidelines
- Building the Evidence for Genomic Tests: Several groups curate, evaluate and synthesize evidence from published research supporting clinical validity and utility of tests to guide clinicians: