The Duke Precision Medicine Program aims to bring proven precision medicine technologies from the basic science portfolio to the clinical settings through both research and clinical programs. Precision medicine technologies are broad-based and include specific tools such as wearables or our family history risk assessment platform, as well as predictive models that incorporate multiple modalities using state of the art scientific principles like machine learning. Housed in the Division of General Internal Medicine in the Duke Department of Medicine, our team is particularly interested in incorporating 'omic technologies, such as genomics, transcriptomics, and epigenomics, into clinical environments to enhance patient care and has broad based expertise in health services research, implementation science, and complex data.
"Precision Medicine is the future of medicine and we are excited to be on the forefront of research, advancements, and discoveries." - Lori Orlando, Director of the Duke Precision Medicine Program
Lori Orlando, MD, MHS, MMCI
Director of the Duke Precision Medicine Program
Learn more about our work
The pace of precision medicine is rapidly accelerating and it’s potential to improve individual and population health is as well. However, precision medicine’s unique complexities make it difficult to incorporate into our existing healthcare infrastructure and processes.
Our goal is to identify and address these challenges so that patients and providers have the data, tools, and resources they need to optimize health.
Our team is dedicated to advancing research in precision medicine through ongoing studies through trial networks housed at Duke University.
- Digital Health and Wear Duke
- GUARDD-US: Genetic testing to understand renal disease disparities across the US through the IGNITE Pragmatic Clinical Trials Network
Our team has developed and implemented various initiatives, programs, and tools, to bring precision medicine into the hands of providers, including both clinicians and pharmacists.
- PHASER: Pharmacogenomics Testing for Veterans program (PHASER), brings pharmacogenomic testing to Veterans across the country receiving care at a VA. Led by Founding Director, Deepak Voora, PHASER uses this type of testing to optimize prescriptions using genetic data from patients to reduce adverse side effects and improve medication outcomes.
- MeTree: Developed by the Duke Precision Medicine Program, MeTree is a web-based, patient-facing risk assessment tool that collects personal health information and family health history.
Education & Training
Educating the next generation of researchers and health care providers in genomics and precision medicine is part of the fabric of our values. We are committed to providing extraordinary mentorship and educational experiences to future genomics researchers, educators, and clinicians.
News & Recognition
See what's happening at the Duke Precision Medicine Program:
Dr. Haga promoted to Full Professor
Congratulations to Susanne Haga, PhD, who received a distinguished academic promotion in the division of General Internal Medicine. Dr. Haga will be promoted to Full Professor, effective May 1, 2023.
DOM Research Quality Virtual Town Hall
Precision Medicine Program’s Lori Orlando to present at Medicine Grand Rounds
Get to know Pamela Williams and how she brought together supporting people and project management
WearDuke expands to provide wearables through Koru curriculum
Clipp-Speer MGR Features Health Equity Leader, Dr. Consuelo Wilkins
GIM Division Update with Interim Chief Dr. William Yancey
By William Yancy, MD
Interim Chief, Division of General Internal Medicine
The Division of General Internal Medicine at Duke strives to improve adult patient, family, community, and population health through exemplary patient care, education, and research. Perhaps most importantly, we have maintained core values of excellence, integrity, kindness, and commitment to health and health equity for our patients and our communities.
2023 Resident Research Day Features Califf Research Award Winners
Berg, Joshi, and McDonald to Receive 2023 DOM Master Clinician Awards
Dr. Wilder Leads Three-Year Study to Improve Health Literacy in Underserved Communities
Q&A Spotlight: Distinguished Professors Christopher Granger and Rana Gupta
Gastronauts: Making Science Democratic—and Other Worthwhile Pursuits
Darwin was not out to change the world when he arrived in Galapagos in 1835, says Diego Bohórquez, PhD, who wasn’t either when he brought a small group of Duke scientists together back in 2014 to talk gut-brain science.
Now, nearly a decade later, Bohórquez thinks he just might.
Crawford, Diehl, Weinberg Receive Department of Medicine 2023 Career Achievement Awards
The Department of Medicine (DOM) is pleased to announce the 2023 recipients of the annual Department of Medicine Career Achievement Award: Jeffrey Crawford, MD, Louis Diehl, MD, and